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Synthesis of a 3′-C-ethynyl-β-d-ribofuranose purine nucleoside library: Discovery of C7-deazapurine analogs as potent antiproliferative nucleosides

European journal of medicinal chemistry, 2018-09, Vol.157, p.248-267

2018

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Preparation and biological evaluation of 1′-cyano-2′-C-methyl pyrimidine nucleosides as HCV NS5B polymerase inhibitors

Bioorganic & medicinal chemistry letters, 2014-07, Vol.24 (14), p.3092-3095

2014

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Synthesis, structural characterization and biological evaluation of 4′-C-methyl- and phenyl-dioxolane pyrimidine and purine nucleosides

Archives of pharmacal research, 2017-05, Vol.40 (5), p.537-549

2017

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Recognition of Artificial Nucleobases by E. coli Purine Nucleoside Phosphorylase versus its Ser90Ala Mutant in the Synthesis of Base-Modified Nucleosides

Chemistry : a European journal, 2015-09, Vol.21 (38), p.13401-13419

2015

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Phosphonated Carbocyclic 2‘-Oxa-3‘-azanucleosides as New Antiretroviral Agents

Journal of medicinal chemistry, 2007-07, Vol.50 (15), p.3747-3750

2007

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The ProTide Prodrug Technology: From the Concept to the Clinic

Journal of medicinal chemistry, 2018-03, Vol.61 (6), p.2211-2226

2018

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Adenosine Kinase Inhibitors. 6. Synthesis, Water Solubility, and Antinociceptive Activity of 5-Phenyl-7-(5-deoxy-β-d-ribofuranosyl)pyrrolo[2,3-d]pyrimidines Substituted at C4 with Glycinamides and Related Compounds

Journal of medicinal chemistry, 2005-12, Vol.48 (24), p.7808-7820

2005

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Synthesis of 6-(het) ary Xylocydine analogues and evaluating their inhibitory activities of CDK1 and CDK2 in vitro

Bioorganic & medicinal chemistry, 2011-12, Vol.19 (23), p.7100-7110

2011

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Preparation of the 2′-Deoxynucleosides of 2,6-Diaminopurine and Isoguanine by Direct Glycosylation

Journal of organic chemistry, 2010-03, Vol.75 (5), p.1360-1365

2010

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Syntheses of 4‘ - C-Ethynyl-β-d-arabino- and 4‘-C-Ethynyl-2‘-deoxy-β-d-ribo-pentofuranosylpyrimidines and -purines and Evaluation of Their Anti-HIV Activity

Journal of medicinal chemistry, 2000-11, Vol.43 (23), p.4516-4525

2000

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Nucleoside Derived Antibiotics to Fight Microbial Drug Resistance: New Utilities for an Established Class of Drugs?

Journal of medicinal chemistry, 2016-12, Vol.59 (23), p.10343-10382

2016

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Chemical synthesis of 4'-thio and 4'-sulfinyl pyrimidine nucleoside analogues

Organic & biomolecular chemistry, 2022-02, Vol.20 (7), p.1401-1406

2022

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Orally Bioavailable Small-Molecule CD73 Inhibitor (OP-5244) Reverses Immunosuppression through Blockade of Adenosine Production

Journal of medicinal chemistry, 2020-09, Vol.63 (18), p.10433-10459

2020

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Synthesis and Anti-Influenza Activity of Pyridine, Pyridazine, and Pyrimidine C‑Nucleosides as Favipiravir (T-705) Analogues

Journal of medicinal chemistry, 2016-05, Vol.59 (10), p.4611-4624

2016

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Proximal fleximer analogues of 2′-deoxy-2′-fluoro-2′-methyl purine nucleos(t)ides: Synthesis and preliminary pharmacokinetic and antiviral evaluation

Bioorganic & medicinal chemistry, 2024-10, Vol.112, p.117898, Article 117898

2024

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Synthesis and Anti-HIV and Anti-HBV Activities of 2‘-Fluoro-2‘,3‘-unsaturated l-Nucleosides

Journal of medicinal chemistry, 1999-04, Vol.42 (7), p.1320-1328

1999

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Synthesis and evaluation of 3′-fluorinated 7-deazapurine nucleosides as antikinetoplastid agents

European journal of medicinal chemistry, 2021-04, Vol.216, p.113290-113290, Article 113290

2021

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Discovery, Synthesis, and Activity Evaluation of Novel Five-Membered Sulfur-Containing Heterocyclic Nucleosides as Potential Anticancer Agents In Vitro and In Vivo

Journal of medicinal chemistry, 2024-08, Vol.67 (15), p.12553-12570

2024

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Structural Modification and Biological Evaluation of 2,8-Disubstituted Adenine and Its Nucleosides as A 2A Adenosine Receptor Antagonists: Exploring the Roles of Ribose at Adenosine Receptors

Journal of medicinal chemistry, 2024-06, Vol.67 (12), p.10490-10507

2024

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Membrane Permeable, Bioreversibly Modified Prodrugs of Nucleoside Diphosphate-γ-Phosphonates

Journal of medicinal chemistry, 2020-10, Vol.63 (20), p.11990-12007

2020

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Antitumor activity and transcriptome sequencing (RNA-seq) analyses of hepatocellular carcinoma cells in response to exposure triterpene-nucleoside conjugates

European journal of medicinal chemistry, 2024-10, Vol.276, p.116635, Article 116635

2024

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Phenoxazine nucleoside derivatives with a multiple activity against RNA and DNA viruses

European journal of medicinal chemistry, 2021-08, Vol.220, p.113467-113467, Article 113467

2021

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2′-β-Methylselenyl nucleos(t)ide analogs as reverse transcriptase inhibitors against diverse HIV mutants

Bioorganic & medicinal chemistry, 2024-08, Vol.110, p.117813, Article 117813

2024

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Synthesis and evaluation of a collection of purine-like C-nucleosides as antikinetoplastid agents

European journal of medicinal chemistry, 2021-02, Vol.212, p.113101, Article 113101

2021

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Synthesis of a 3′-C-ethynyl-β-d-ribofuranose purine nucleoside library: Discovery of C7-deazapurine analogs as potent antiproliferative nucleosides

Preparation and biological evaluation of 1′-cyano-2′-C-methyl pyrimidine nucleosides as HCV NS5B polymerase inhibitors

Synthesis, structural characterization and biological evaluation of 4′-C-methyl- and phenyl-dioxolane pyrimidine and purine nucleosides

Recognition of Artificial Nucleobases by E. coli Purine Nucleoside Phosphorylase versus its Ser90Ala Mutant in the Synthesis of Base-Modified Nucleosides

Phosphonated Carbocyclic 2‘-Oxa-3‘-azanucleosides as New Antiretroviral Agents

The ProTide Prodrug Technology: From the Concept to the Clinic

Adenosine Kinase Inhibitors. 6. Synthesis, Water Solubility, and Antinociceptive Activity of 5-Phenyl-7-(5-deoxy-β-d-ribofuranosyl)pyrrolo[2,3-d]pyrimidines Substituted at C4 with Glycinamides and Related Compounds

Synthesis of 6-(het) ary Xylocydine analogues and evaluating their inhibitory activities of CDK1 and CDK2 in vitro

Preparation of the 2′-Deoxynucleosides of 2,6-Diaminopurine and Isoguanine by Direct Glycosylation

Syntheses of 4‘ - C-Ethynyl-β-d-arabino- and 4‘-C-Ethynyl-2‘-deoxy-β-d-ribo-pentofuranosylpyrimidines and -purines and Evaluation of Their Anti-HIV Activity

Nucleoside Derived Antibiotics to Fight Microbial Drug Resistance: New Utilities for an Established Class of Drugs?

Chemical synthesis of 4'-thio and 4'-sulfinyl pyrimidine nucleoside analogues

Orally Bioavailable Small-Molecule CD73 Inhibitor (OP-5244) Reverses Immunosuppression through Blockade of Adenosine Production

Synthesis and Anti-Influenza Activity of Pyridine, Pyridazine, and Pyrimidine C‑Nucleosides as Favipiravir (T-705) Analogues

Proximal fleximer analogues of 2′-deoxy-2′-fluoro-2′-methyl purine nucleos(t)ides: Synthesis and preliminary pharmacokinetic and antiviral evaluation

Synthesis and Anti-HIV and Anti-HBV Activities of 2‘-Fluoro-2‘,3‘-unsaturated l-Nucleosides

Synthesis and evaluation of 3′-fluorinated 7-deazapurine nucleosides as antikinetoplastid agents

Discovery, Synthesis, and Activity Evaluation of Novel Five-Membered Sulfur-Containing Heterocyclic Nucleosides as Potential Anticancer Agents In Vitro and In Vivo

Structural Modification and Biological Evaluation of 2,8-Disubstituted Adenine and Its Nucleosides as A 2A Adenosine Receptor Antagonists: Exploring the Roles of Ribose at Adenosine Receptors

The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer

Membrane Permeable, Bioreversibly Modified Prodrugs of Nucleoside Diphosphate-γ-Phosphonates

Antitumor activity and transcriptome sequencing (RNA-seq) analyses of hepatocellular carcinoma cells in response to exposure triterpene-nucleoside conjugates

Phenoxazine nucleoside derivatives with a multiple activity against RNA and DNA viruses

2′-β-Methylselenyl nucleos(t)ide analogs as reverse transcriptase inhibitors against diverse HIV mutants

Synthesis and evaluation of a collection of purine-like C-nucleosides as antikinetoplastid agents

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