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The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease

Neuron (Cambridge, Mass.), 2014-05, Vol.82 (4), p.756-771

2014

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Beyond the neuron-cellular interactions early in Alzheimer disease pathogenesis

Nature reviews. Neuroscience, 2019-02, Vol.20 (2), p.94-108

2019

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Apoptotic and non-apoptotic roles of caspases in neuronal physiology and pathophysiology

Nature reviews. Neuroscience, 2012-06, Vol.13 (6), p.395-406

2012

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Propagation of Tau Pathology in a Model of Early Alzheimer's Disease

Neuron (Cambridge, Mass.), 2012-02, Vol.73 (4), p.685-697

2012

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Local Nucleation of Microtubule Bundles through Tubulin Concentration into a Condensed Tau Phase

Cell reports (Cambridge), 2017-09, Vol.20 (10), p.2304-2312

2017

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Tau induces blood vessel abnormalities and angiogenesis-related gene expression in P301L transgenic mice and human Alzheimer’s disease

Proceedings of the National Academy of Sciences - PNAS, 2018-02, Vol.115 (6), p.E1289-E1298

2018

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Machine learning identifies candidates for drug repurposing in Alzheimer's disease

Nature communications, 2021-02, Vol.12 (1), p.1033-13, Article 1033

2021

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Systematic review and meta-analysis of human transcriptomics reveals neuroinflammation, deficient energy metabolism, and proteostasis failure across neurodegeneration

Neurobiology of disease, 2021-02, Vol.149, p.105225-105225, Article 105225

2021

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The role of microglia in processing and spreading of bioactive tau seeds in Alzheimer's disease

Journal of neuroinflammation, 2018-09, Vol.15 (1), p.269-269, Article 269

2018

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Characterization of the 18 kDa translocator protein (TSPO) expression in post‐mortem normal and Alzheimer's disease brains

Brain pathology (Zurich, Switzerland), 2020-01, Vol.30 (1), p.151-164

2020

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Meta-analysis of mouse transcriptomic studies supports a context-dependent astrocyte reaction in acute CNS injury versus neurodegeneration

Journal of neuroinflammation, 2020-07, Vol.17 (1), p.227-227, Article 227

2020

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Tau Propagation, Different Tau Phenotypes, and Prion-like Properties of Tau

Neuron (Cambridge, Mass.), 2014-06, Vol.82 (6), p.1189-1190

Hyman, Bradley T.

2014

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Novel allele-dependent role for APOE in controlling the rate of synapse pruning by astrocytes

Proceedings of the National Academy of Sciences - PNAS, 2016-09, Vol.113 (36), p.10186-10191

2016

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Poor Performance on a Preoperative Cognitive Screening Test Predicts Postoperative Complications in Older Orthopedic Surgical Patients

Anesthesiology (Philadelphia), 2017-11, Vol.127 (5), p.765-774

2017

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Synchronous Hyperactivity and Intercellular Calcium Waves in Astrocytes in Alzheimer Mice

Science (American Association for the Advancement of Science), 2009-02, Vol.323 (5918), p.1211-1215

2009

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Oxidative stress and lipid peroxidation are upstream of amyloid pathology

Neurobiology of disease, 2015-12, Vol.84, p.109-119

2015

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Regulation of tau internalization, degradation, and seeding by LRP1 reveals multiple pathways for tau catabolism

The Journal of biological chemistry, 2021-01, Vol.296, p.100715-100715, Article 100715

2021

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Mechanisms of protein seeding in neurodegenerative diseases

JAMA neurology, 2013-03, Vol.70 (3), p.304

2013

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Synergy between amyloid-β and tau in Alzheimer's disease

Nature neuroscience, 2020-10, Vol.23 (10), p.1183-1193

2020

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Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice

Nature communications, 2021-04, Vol.12 (1), p.2238-2238, Article 2238

2021

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Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain

Nature communications, 2015-10, Vol.6 (1), p.8490-8490, Article 8490

2015

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National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

Acta neuropathologica, 2012-01, Vol.123 (1), p.1-11

2012

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Formation, release, and internalization of stable tau oligomers in cells

Journal of neurochemistry, 2016-12, Vol.139 (6), p.1163-1174

2016

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Alzheimer's disease: synapses gone cold

Molecular neurodegeneration, 2011-08, Vol.6 (1), p.63-63, Article 63

2011

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The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease

Beyond the neuron-cellular interactions early in Alzheimer disease pathogenesis

Apoptotic and non-apoptotic roles of caspases in neuronal physiology and pathophysiology

Propagation of Tau Pathology in a Model of Early Alzheimer's Disease

Local Nucleation of Microtubule Bundles through Tubulin Concentration into a Condensed Tau Phase

Tau induces blood vessel abnormalities and angiogenesis-related gene expression in P301L transgenic mice and human Alzheimer’s disease

Machine learning identifies candidates for drug repurposing in Alzheimer's disease

Systematic review and meta-analysis of human transcriptomics reveals neuroinflammation, deficient energy metabolism, and proteostasis failure across neurodegeneration

The role of microglia in processing and spreading of bioactive tau seeds in Alzheimer's disease

Characterization of the 18 kDa translocator protein (TSPO) expression in post‐mortem normal and Alzheimer's disease brains

Meta-analysis of mouse transcriptomic studies supports a context-dependent astrocyte reaction in acute CNS injury versus neurodegeneration

Tau Propagation, Different Tau Phenotypes, and Prion-like Properties of Tau

Novel allele-dependent role for APOE in controlling the rate of synapse pruning by astrocytes

Poor Performance on a Preoperative Cognitive Screening Test Predicts Postoperative Complications in Older Orthopedic Surgical Patients

Synchronous Hyperactivity and Intercellular Calcium Waves in Astrocytes in Alzheimer Mice

Oxidative stress and lipid peroxidation are upstream of amyloid pathology

Regulation of tau internalization, degradation, and seeding by LRP1 reveals multiple pathways for tau catabolism

Mechanisms of protein seeding in neurodegenerative diseases

Synergy between amyloid-β and tau in Alzheimer's disease

Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice

Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score

Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain

National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

Formation, release, and internalization of stable tau oligomers in cells

Alzheimer's disease: synapses gone cold

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