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SB-243213; a selective 5-HT2C receptor inverse agonist with improved anxiolytic profile : Lack of tolerance and withdrawal anxiety

Neuropharmacology, 2001-08, Vol.41 (2), p.186-199

2001

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[3H]-SB-269970 radiolabels 5-HT7 receptors in rodent, pig and primate brain tissues

Neuropharmacology, 2002, Vol.42 (1), p.74-81

2002

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The expression of GABA(B1) and GABA(B2) receptor subunits in the cNS differs from that in peripheral tissues

Neuroscience, 2000-01, Vol.100 (1), p.155-170

2000

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The behavioural effects of corticotropin-releasing factor-related peptides in rats

Psychopharmacologia, 1998-07, Vol.138 (2), p.124-132

1998

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Implantation of a Slow Release Corticosterone Pellet Induces Long-Term Alterations in Serotonergic Neurochemistry in the Rat Brain

Journal of neuroendocrinology, 2003-06, Vol.15 (6), p.607-613

2003

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Functional effects of the muscarinic receptor agonist, xanomeline, at 5‐HT1 and 5‐HT2 receptors

British journal of pharmacology, 1998-12, Vol.125 (7), p.1413-1420

1998

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Cannabinoid activation of recombinant and endogenous vanilloid receptors

European journal of pharmacology, 2001-07, Vol.424 (3), p.211-219

2001

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Proposals for the classification and nomenclature of functional receptors for 5-hydroxytryptamine

Neuropharmacology, 1986-06, Vol.25 (6), p.563-576

1986

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A functional correlate for the dihydropyridine binding site in rat brain

Nature (London), 1985-03, Vol.314 (6006), p.94-96

1985

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SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist

Neuropharmacology, 1997-04, Vol.36 (4-5), p.609-620

1997

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Characterization of MDL 73005EF as a 5‐HT1A selective ligand and its effects in animal models of anxiety: comparison with buspirone, 8‐OH‐DPAT and diazepam

British journal of pharmacology, 1990-02, Vol.99 (2), p.343-349

1990

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(-)Baclofen decreases neurotransmitter release in the mammalian CNS by an action at a novel GABA receptor

Nature (London), 1980-01, Vol.283 (5742), p.92-94

1980

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Effect of haloperidol and (−)-sulpiride on dopamine agonist-induced hypoactivity

Neuropharmacology, 1995-04, Vol.34 (4), p.449-455

1995

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Graphics computer-aided receptor mapping as a predictive tool for drug design: development of potent, selective, and stereospecific ligands for the 5-HT1A receptor

Journal of medicinal chemistry, 1988-06, Vol.31 (6), p.1087-1093

1988

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Pharmacological analysis of the behavioural and thermoregulatory effects of the putative 5-HT1 receptor agonist, RU 24969, in the rat

Neuropharmacology, 1986-08, Vol.25 (8), p.877-886

1986

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Characterization of the binding of [3H]‐SB‐204269, a radiolabelled form of the new anticonvulsant SB‐204269, to a novel binding site in rat brain membranes

British journal of pharmacology, 1997-08, Vol.121 (8), p.1687-1691

1997

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Influence of peptide CRF receptor antagonists upon the behavioural effects of human/rat CRF

European journal of pharmacology, 1999-06, Vol.373 (2), p.141-145

1999

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1-[2-[(Heteroaryloxy)heteroaryl]carbamoyl]indolines : Novel and selective 5-HT2C receptor inverse agonists with potential as antidepressant/anxiolytic agents

Bioorganic & medicinal chemistry letters, 2000-08, Vol.10 (16), p.1863-1866

2000

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1-[2-[(Heteroarylmethoxy)aryl]carbamoyl]indolines are selective and orally active 5-HT2C receptor inverse agonists

Bioorganic & medicinal chemistry letters, 2000-08, Vol.10 (16), p.1867-1870

2000

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MK-212 increases rat plasma ACTH concentration by activation of the 5-HT1C receptor subtype

Neuroscience letters, 1989-10, Vol.105 (1-2), p.174-176

1989

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In vitro characterisation of the muscarinic receptor partial agonist, sabcomeline, in rat cortical and heart membranes

European journal of pharmacology, 1999-04, Vol.370 (1), p.69-77

1999

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The calcium channel activator, Bay K 8644, enhances K+-evoked efflux of acetylcholine and noradrenaline from rat brain slices

Naunyn-Schmiedeberg's archives of pharmacology, 1985-10, Vol.331 (1), p.114-116

MIDDLEMISS, D. N

1985

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Blockade of the central 5-HT autoreceptor by β-adrenoceptor antagonists

European journal of pharmacology, 1986-01, Vol.120 (1), p.51-56

Middlemiss, Derek N.

1986

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Autoradiographic localization of 5-CT-insensitive 5-HT1-like recognition sites in guinea pig and rat brain

Neuropharmacology, 1996-02, Vol.35 (2), p.223-229

1996

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The putative 5-HT1 receptor agonist, RU 24969, inhibits the efflux of 5-hydroxytryptamine from rat frontal cortex slices by stimulation of the 5-HT autoreceptor

Journal of pharmacy and pharmacology, 1985-06, Vol.37 (6), p.434-437

Middlemiss, Derek N.

1985

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SB-243213; a selective 5-HT2C receptor inverse agonist with improved anxiolytic profile : Lack of tolerance and withdrawal anxiety

[3H]-SB-269970 radiolabels 5-HT7 receptors in rodent, pig and primate brain tissues

The expression of GABA(B1) and GABA(B2) receptor subunits in the cNS differs from that in peripheral tissues

The behavioural effects of corticotropin-releasing factor-related peptides in rats

Implantation of a Slow Release Corticosterone Pellet Induces Long-Term Alterations in Serotonergic Neurochemistry in the Rat Brain

Functional effects of the muscarinic receptor agonist, xanomeline, at 5‐HT1 and 5‐HT2 receptors

Cannabinoid activation of recombinant and endogenous vanilloid receptors

Proposals for the classification and nomenclature of functional receptors for 5-hydroxytryptamine

A functional correlate for the dihydropyridine binding site in rat brain

SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist

Characterization of MDL 73005EF as a 5‐HT1A selective ligand and its effects in animal models of anxiety: comparison with buspirone, 8‐OH‐DPAT and diazepam

(-)Baclofen decreases neurotransmitter release in the mammalian CNS by an action at a novel GABA receptor

Effect of haloperidol and (−)-sulpiride on dopamine agonist-induced hypoactivity

Graphics computer-aided receptor mapping as a predictive tool for drug design: development of potent, selective, and stereospecific ligands for the 5-HT1A receptor

Pharmacological analysis of the behavioural and thermoregulatory effects of the putative 5-HT1 receptor agonist, RU 24969, in the rat

Characterization of the binding of [3H]‐SB‐204269, a radiolabelled form of the new anticonvulsant SB‐204269, to a novel binding site in rat brain membranes

Influence of peptide CRF receptor antagonists upon the behavioural effects of human/rat CRF

1-[2-[(Heteroaryloxy)heteroaryl]carbamoyl]indolines : Novel and selective 5-HT2C receptor inverse agonists with potential as antidepressant/anxiolytic agents

1-[2-[(Heteroarylmethoxy)aryl]carbamoyl]indolines are selective and orally active 5-HT2C receptor inverse agonists

MK-212 increases rat plasma ACTH concentration by activation of the 5-HT1C receptor subtype

In vitro characterisation of the muscarinic receptor partial agonist, sabcomeline, in rat cortical and heart membranes

The calcium channel activator, Bay K 8644, enhances K+-evoked efflux of acetylcholine and noradrenaline from rat brain slices

Blockade of the central 5-HT autoreceptor by β-adrenoceptor antagonists

Autoradiographic localization of 5-CT-insensitive 5-HT1-like recognition sites in guinea pig and rat brain

The putative 5-HT1 receptor agonist, RU 24969, inhibits the efflux of 5-hydroxytryptamine from rat frontal cortex slices by stimulation of the 5-HT autoreceptor

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