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Structural snapshots of the minimal PKS system responsible for octaketide biosynthesis

Nature chemistry, 2020-08, Vol.12 (8), p.755-763

2020

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Cytochrome P450 Catalyzes Benzene Ring Formation in the Biosynthesis of Trialkyl‐Substituted Aromatic Polyketides

Angewandte Chemie International Edition, 2023-01, Vol.62 (5), p.e202214026-n/a

International ed. in English, 2023

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Lugdunomycin, an Angucycline‐Derived Molecule with Unprecedented Chemical Architecture

Angewandte Chemie International Edition, 2019-02, Vol.58 (9), p.2809-2814

International ed. in English, 2019

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Accramycin A, a New Aromatic Polyketide, from the Soil Bacterium, Streptomyces sp. MA37

Molecules (Basel, Switzerland), 2019-09, Vol.24 (18), p.3384

2019

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Architecture of full-length type I modular polyketide synthases revealed by X-ray crystallography, cryo-electron microscopy, and AlphaFold2

Natural product reports, 2024-08, Vol.41 (8), p.1219-1234

2024

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Toblerols: Cyclopropanol‐Containing Polyketide Modulators of Antibiosis in Methylobacteria

Angewandte Chemie International Edition, 2018-01, Vol.57 (4), p.977-981

International ed. in English, 2018

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Polyketide Synthase Modules Redefined

Angewandte Chemie International Edition, 2017-04, Vol.56 (17), p.4658-4660

Keatinge‐Clay, Adrian T.

International ed. in English, 2017

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Engineering strategies for rational polyketide synthase design

Natural product reports, 2018-10, Vol.35 (1), p.17-181

2018

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Isolation and Structure Elucidation of JBIR-157, a Skeletally Novel Aromatic Polyketide Produced by the Heterologous Expression of a Cryptic Gene Cluster

Chemical and Pharmaceutical Bulletin, 2024/05/16, Vol.72(5), pp.475-479

2024

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Molecular Basis for the Biosynthesis of an Unusual Chain-Fused Polyketide, Gregatin A

Journal of the American Chemical Society, 2020-05, Vol.142 (18), p.8464-8472

2020

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Genomics-Driven Discovery of Burkholderic Acid, a Noncanonical, Cryptic Polyketide from Human Pathogenic Burkholderia Species

Angewandte Chemie (International ed.), 2012-11, Vol.51 (46), p.11611-11615

International ed. in English, 2012

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Insect‐Associated Bacteria Assemble the Antifungal Butenolide Gladiofungin by Non‐Canonical Polyketide Chain Termination

Angewandte Chemie International Edition, 2020-12, Vol.59 (51), p.23122-23126

International ed. in English, 2020

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Metabolic Engineering and Synthetic Biology Approaches for the Heterologous Production of Aromatic Polyketides

International journal of molecular sciences, 2023-05, Vol.24 (10), p.8923

2023

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Polyketide Cyclizations for the Synthesis of Polyaromatics

Angewandte Chemie International Edition, 2020-04, Vol.59 (18), p.6975-6983

International ed. in English, 2020

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Cyclopropanol Warhead in Malleicyprol Confers Virulence of Human‐ and Animal‐Pathogenic Burkholderia Species

Angewandte Chemie International Edition, 2019-10, Vol.58 (40), p.14129-14133

International ed. in English, 2019

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Resorculins: hybrid polyketide macrolides from Streptomyces sp. MST-91080

Organic & biomolecular chemistry, 2023-03, Vol.21 (12), p.2531-2538

2023

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Loss of Single‐Domain Function in a Modular Assembly Line Alters the Size and Shape of a Complex Polyketide

Angewandte Chemie International Edition, 2019-12, Vol.58 (50), p.18252-18256

International ed. in English, 2019

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Challenging Aromaticity: Revealing a Thioesterase Domain in a Fungal Nonreducing Polyketide Synthase Governing the Production of 3‑Methylene Isochromanone

Organic letters, 2024-08, Vol.26 (30), p.6303-6308

2024

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Nonproteinogenic Amino Acid Building Blocks for Nonribosomal Peptide and Hybrid Polyketide Scaffolds

Angewandte Chemie (International ed.), 2013-07, Vol.52 (28), p.7098-7124

International ed. in English, 2013

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Diels–Alder Reactions During the Biosynthesis of Sorbicillinoids

Angewandte Chemie International Edition, 2020-03, Vol.59 (14), p.5816-5822

International ed. in English, 2020

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Gatekeeping Ketosynthases Dictate Initiation of Assembly Line Biosynthesis of Pyrrolic Polyketides

Journal of the American Chemical Society, 2021-05, Vol.143 (20), p.7617-7622

2021

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Antibacterial polyketides from Bacillus amyloliquefaciens associated with edible red seaweed Laurenciae papillosa

Food chemistry, 2017-03, Vol.218, p.427-434

2017

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Mechanism Behind the Programmed Biosynthesis of Heterotrimeric Fungal Depside Thielavin A

Angewandte Chemie International Edition, 2024-05, Vol.63 (20), p.e202402663-n/a

International ed. in English, 2024

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Navigating the Fungal Polyketide Chemical Space: From Genes to Molecules

Journal of organic chemistry, 2012-11, Vol.77 (22), p.9933-9953

2012

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How Acyl Carrier Proteins (ACPs) Direct Fatty Acid and Polyketide Biosynthesis

Angewandte Chemie International Edition, 2024-01, Vol.63 (4), p.e202312476-n/a

International ed. in English, 2024

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Structural snapshots of the minimal PKS system responsible for octaketide biosynthesis

Cytochrome P450 Catalyzes Benzene Ring Formation in the Biosynthesis of Trialkyl‐Substituted Aromatic Polyketides

Lugdunomycin, an Angucycline‐Derived Molecule with Unprecedented Chemical Architecture

Accramycin A, a New Aromatic Polyketide, from the Soil Bacterium, Streptomyces sp. MA37

Architecture of full-length type I modular polyketide synthases revealed by X-ray crystallography, cryo-electron microscopy, and AlphaFold2

Toblerols: Cyclopropanol‐Containing Polyketide Modulators of Antibiosis in Methylobacteria

Polyketide Synthase Modules Redefined

Engineering strategies for rational polyketide synthase design

Isolation and Structure Elucidation of JBIR-157, a Skeletally Novel Aromatic Polyketide Produced by the Heterologous Expression of a Cryptic Gene Cluster

Molecular Basis for the Biosynthesis of an Unusual Chain-Fused Polyketide, Gregatin A

Genomics-Driven Discovery of Burkholderic Acid, a Noncanonical, Cryptic Polyketide from Human Pathogenic Burkholderia Species

Insect‐Associated Bacteria Assemble the Antifungal Butenolide Gladiofungin by Non‐Canonical Polyketide Chain Termination

Metabolic Engineering and Synthetic Biology Approaches for the Heterologous Production of Aromatic Polyketides

Polyketide Cyclizations for the Synthesis of Polyaromatics

Cyclopropanol Warhead in Malleicyprol Confers Virulence of Human‐ and Animal‐Pathogenic Burkholderia Species

Resorculins: hybrid polyketide macrolides from Streptomyces sp. MST-91080

Loss of Single‐Domain Function in a Modular Assembly Line Alters the Size and Shape of a Complex Polyketide

Challenging Aromaticity: Revealing a Thioesterase Domain in a Fungal Nonreducing Polyketide Synthase Governing the Production of 3‑Methylene Isochromanone

Nonproteinogenic Amino Acid Building Blocks for Nonribosomal Peptide and Hybrid Polyketide Scaffolds

Diels–Alder Reactions During the Biosynthesis of Sorbicillinoids

Gatekeeping Ketosynthases Dictate Initiation of Assembly Line Biosynthesis of Pyrrolic Polyketides

Antibacterial polyketides from Bacillus amyloliquefaciens associated with edible red seaweed Laurenciae papillosa

Mechanism Behind the Programmed Biosynthesis of Heterotrimeric Fungal Depside Thielavin A

Navigating the Fungal Polyketide Chemical Space: From Genes to Molecules

How Acyl Carrier Proteins (ACPs) Direct Fatty Acid and Polyketide Biosynthesis

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