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Pharmacokinetics and metabolism of [14C]eplerenone after oral administration to humans

Drug metabolism and disposition, 2003-11, Vol.31 (11), p.1448

2003

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Dynamic modeling of cytochrome P450 inhibition in vitro: impact of inhibitor depletion on IC₅₀ shift

Drug metabolism and disposition, 2013-07, Vol.41 (7), p.1433

2013

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Species difference in glucuronidation formation kinetics with a selective mTOR inhibitor

Drug metabolism and disposition, 2014-04, Vol.42 (4), p.707

2014

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Applications of parallel synthetic lead hopping and pharmacophore-based virtual screening in the discovery of efficient glycine receptor potentiators

European journal of medicinal chemistry, 2017-09, Vol.137, p.63-75

2017

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Involvement of CYP3A in the metabolism of eplerenone in humans and dogs: differential metabolism by CYP3A4 and CYP3A5

Drug metabolism and disposition, 2002-12, Vol.30 (12), p.1344

2002

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Impact of hydrolysis-mediated clearance on the pharmacokinetics of novel anaplastic lymphoma kinase inhibitors

Drug metabolism and disposition, 2013-01, Vol.41 (1), p.238

2013

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Discovery and Optimization of Triazolopyridazines as Potent and Selective Inhibitors of the c-Met Kinase

Journal of medicinal chemistry, 2008-05, Vol.51 (10), p.2879-2882

2008

Volltextzugriff (PDF)

Use of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical Species

Drug metabolism and disposition, 2019-10, Vol.47 (10), p.1111-1121

2019

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Discovery and optimization of a potent and selective triazolopyridinone series of c-Met inhibitors

Bioorganic & medicinal chemistry letters, 2012-06, Vol.22 (12), p.4089-4093

2012

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N-methylacetamide analog of salvinorin A: a highly potent and selective kappa-opioid receptor agonist with oral efficacy

The Journal of pharmacology and experimental therapeutics, 2008-01, Vol.324 (1), p.188

2008

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Pharmacokinetics and metabolism of [14C]eplerenone after oral administration to humans

Dynamic modeling of cytochrome P450 inhibition in vitro: impact of inhibitor depletion on IC₅₀ shift

Species difference in glucuronidation formation kinetics with a selective mTOR inhibitor

Applications of parallel synthetic lead hopping and pharmacophore-based virtual screening in the discovery of efficient glycine receptor potentiators

Involvement of CYP3A in the metabolism of eplerenone in humans and dogs: differential metabolism by CYP3A4 and CYP3A5

Impact of hydrolysis-mediated clearance on the pharmacokinetics of novel anaplastic lymphoma kinase inhibitors

Discovery and Optimization of Triazolopyridazines as Potent and Selective Inhibitors of the c-Met Kinase

Use of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical Species

Evaluation of a Series of Naphthamides as Potent, Orally Active Vascular Endothelial Growth Factor Receptor-2 Tyrosine Kinase Inhibitors

Discovery and optimization of a potent and selective triazolopyridinone series of c-Met inhibitors

N-methylacetamide analog of salvinorin A: a highly potent and selective kappa-opioid receptor agonist with oral efficacy

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