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NMR Spectroscopy of the Main Protease of SARS‐CoV‐2 and Fragment‐Based Screening Identify Three Protein Hotspots and an Antiviral Fragment

Angewandte Chemie International Edition, 2021-11, Vol.60 (48), p.25428-25435

International ed. in English, 2021

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Phosphorylation and O-GlcNAcylation of the PHF-1 Epitope of Tau Protein Induce Local Conformational Changes of the C-Terminus and Modulate Tau Self-Assembly Into Fibrillar Aggregates

Frontiers in molecular neuroscience, 2021-06, Vol.14, p.661368-661368

2021

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Dynamic interactions and Ca2+-binding modulate the holdase-type chaperone activity of S100B preventing tau aggregation and seeding

Nature communications, 2021-11, Vol.12 (1), p.6292-6292, Article 6292

2021

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A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein

The Journal of biological chemistry, 2024-04, Vol.300 (4), p.107163-107163, Article 107163

2024

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Structural Basis of Tau Interaction With BIN1 and Regulation by Tau Phosphorylation

Frontiers in molecular neuroscience, 2018-11, Vol.11, p.421-421

2018

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Cyclophilin A allows the allosteric regulation of a structural motif in the disordered domain 2 of NS5A and thereby fine-tunes HCV RNA replication

The Journal of biological chemistry, 2019-08, Vol.294 (35), p.13171-13185

2019

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Set-up and screening of a fragment library targeting the 14-3-3 protein interface

MedChemComm, 2019-10, Vol.1 (1), p.1796-182

2019

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A functional fragment of Tau forms fibers without the need for an intermolecular cysteine bridge

Biochemical and biophysical research communications, 2014-03, Vol.445 (2), p.299-303

2014

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Metabolic phenotyping of human plasma by 1H‐NMR at high and medium magnetic field strengths: a case study for lung cancer

Magnetic resonance in chemistry, 2017-08, Vol.55 (8), p.706-713

2017

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Flexibility of Oxidized and Reduced States of the Chloroplast Regulatory Protein CP12 in Isolation and in Cell Extracts

Biomolecules (Basel, Switzerland), 2021-05, Vol.11 (5), p.701

2021

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Hepatitis E virus RNA‐dependent RNA polymerase is involved in RNA replication and infectious particle production

Hepatology (Baltimore, Md.), 2022-01, Vol.75 (1), p.170-181

2022

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Making 1H–1H Couplings More Accessible and Accurate with Selective 2DJ NMR Experiments Aided by 13C Satellites

Analytical chemistry (Washington), 2024-05, Vol.96 (18), p.7056-7064

2024

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Regulation of the interaction between the neuronal BIN1 isoform 1 and Tau proteins – role of the SH3 domain

The FEBS journal, 2017-10, Vol.284 (19), p.3218-3229

2017

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Divide, conquer and reconstruct: How to solve the 3D structure of recalcitrant Micro-Exon Gene (MEG) protein from Schistosoma mansoni

PloS one, 2023-08, Vol.18 (8), p.e0289444

2023

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Characterization of Neuronal Tau Protein as a Target of Extracellular Signal-regulated Kinase

The Journal of biological chemistry, 2016-04, Vol.291 (14), p.7742-7753

2016

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NMR reveals the intrinsically disordered domain 2 of NS5A protein as an allosteric regulator of the hepatitis C virus RNA polymerase NS5B

The Journal of biological chemistry, 2017-11, Vol.292 (44), p.18024-18043

2017

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Backbone NMR resonance assignment of the apo human Tsg101-UEV domain

Biomolecular NMR assignments, 2023-06, Vol.17 (1), p.49-54

2023

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1H, 13C and 15N chemical shift backbone resonance NMR assignment of tobacco calmodulin 2

Biomolecular NMR assignments, 2022, Vol.16 (1), p.63-66

2022

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Backbone chemical shift assignments of human 14-3-3σ

Biomolecular NMR assignments, 2019-04, Vol.13 (1), p.103-107

2019

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Interaction study between HCV NS5A-D2 and NS5B using 19F NMR

Journal of biomolecular NMR, 2018, Vol.70 (1), p.67-76

2018

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BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation

Acta neuropathologica, 2019-10, Vol.138 (4), p.631-652

2019

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NMR Spectroscopy of the Main Protease of SARS‐CoV‐2 and Fragment‐Based Screening Identify Three Protein Hotspots and an Antiviral Fragment

Angewandte Chemie, 2021-11, Vol.133 (48), p.25632-25639

2021

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Studying Intrinsically Disordered Proteins under True InVivo Conditions by Combined Cross-Polarization and Carbonyl-Detection NMR Spectroscopy

Angewandte Chemie, 2016-06, Vol.128 (26), p.7544-7548

2016

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NMR Spectroscopy of the Main Protease of SARS‐CoV‐2 and Fragment‐Based Screening Identify Three Protein Hotspots and an Antiviral Fragment

Phosphorylation and O-GlcNAcylation of the PHF-1 Epitope of Tau Protein Induce Local Conformational Changes of the C-Terminus and Modulate Tau Self-Assembly Into Fibrillar Aggregates

Dynamic interactions and Ca2+-binding modulate the holdase-type chaperone activity of S100B preventing tau aggregation and seeding

A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein

Structural Basis of Tau Interaction With BIN1 and Regulation by Tau Phosphorylation

Cyclophilin A allows the allosteric regulation of a structural motif in the disordered domain 2 of NS5A and thereby fine-tunes HCV RNA replication

Set-up and screening of a fragment library targeting the 14-3-3 protein interface

A functional fragment of Tau forms fibers without the need for an intermolecular cysteine bridge

Metabolic phenotyping of human plasma by 1H‐NMR at high and medium magnetic field strengths: a case study for lung cancer

Flexibility of Oxidized and Reduced States of the Chloroplast Regulatory Protein CP12 in Isolation and in Cell Extracts

Hepatitis E virus RNA‐dependent RNA polymerase is involved in RNA replication and infectious particle production

Making 1H–1H Couplings More Accessible and Accurate with Selective 2DJ NMR Experiments Aided by 13C Satellites

Regulation of the interaction between the neuronal BIN1 isoform 1 and Tau proteins – role of the SH3 domain

Divide, conquer and reconstruct: How to solve the 3D structure of recalcitrant Micro-Exon Gene (MEG) protein from Schistosoma mansoni

Characterization of Neuronal Tau Protein as a Target of Extracellular Signal-regulated Kinase

NMR reveals the intrinsically disordered domain 2 of NS5A protein as an allosteric regulator of the hepatitis C virus RNA polymerase NS5B

Backbone NMR resonance assignment of the apo human Tsg101-UEV domain

1H, 13C and 15N chemical shift backbone resonance NMR assignment of tobacco calmodulin 2

Backbone chemical shift assignments of human 14-3-3σ

Interaction study between HCV NS5A-D2 and NS5B using 19F NMR

BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation

NMR Spectroscopy of the Main Protease of SARS‐CoV‐2 and Fragment‐Based Screening Identify Three Protein Hotspots and an Antiviral Fragment

Studying Intrinsically Disordered Proteins under True InVivo Conditions by Combined Cross-Polarization and Carbonyl-Detection NMR Spectroscopy

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