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Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus

Nature reviews. Endocrinology, 2016-11, Vol.12 (11), p.633

2016

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Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

Cell metabolism, 2011-11, Vol.14 (5), p.612-622

2011

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Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle

Proceedings of the National Academy of Sciences - PNAS, 2018-07, Vol.115 (30), p.7789-7794

2018

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Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy

Nature medicine, 2013-08, Vol.19 (8), p.1039-1046

2013

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Human skeletal muscle mitochondrial dynamics in relation to oxidative capacity and insulin sensitivity

Diabetologia, 2021-02, Vol.64 (2), p.424-436

2021

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Perilipin 2 Improves Insulin Sensitivity in Skeletal Muscle Despite Elevated Intramuscular Lipid Levels

Diabetes (New York, N.Y.), 2012-11, Vol.61 (11), p.2679-2690

2012

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Nine Months of Combined Training Improves Ex Vivo Skeletal Muscle Metabolism in Individuals With Type 2 Diabetes

The journal of clinical endocrinology and metabolism, 2013-04, Vol.98 (4), p.1694-1702

2013

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Skeletal muscle mitochondrial network dynamics in metabolic disorders and aging

Trends in molecular medicine, 2021-11, Vol.27 (11), p.1033-1044

2021

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Long-echo time MR spectroscopy for skeletal muscle acetylcarnitine detection

The Journal of clinical investigation, 2014-11, Vol.124 (11), p.4915-4925

2014

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Metabolic disturbances of non-alcoholic fatty liver resemble the alterations typical for type 2 diabetes

Clinical science (1979), 2017-08, Vol.131 (15), p.1905

2017

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Evidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans

Diabetes (New York, N.Y.), 2015-04, Vol.64 (4), p.1193-1201

2015

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Mitochondrial dysfunction and lipotoxicity

Biochimica et biophysica acta, 2010-03, Vol.1801 (3), p.266-271

2010

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High Oxidative Capacity Due to Chronic Exercise Training Attenuates Lipid-Induced Insulin Resistance

Diabetes (New York, N.Y.), 2012-10, Vol.61 (10), p.2472-2478

2012

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Intramyocellular lipid droplets and insulin sensitivity, the human perspective

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2017-10, Vol.1862 (10), p.1242-1249

2017

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The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria

Histochemistry and cell biology, 2012-02, Vol.137 (2), p.205-216

2012

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Re-evaluating lipotoxic triggers in skeletal muscle: Relating intramyocellular lipid metabolism to insulin sensitivity

Progress in lipid research, 2012, Vol.51 (1), p.36-49

2012

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Effect of β2-agonist treatment on insulin-stimulated peripheral glucose disposal in healthy men in a randomised placebo-controlled trial

Nature communications, 2023-01, Vol.14 (1), p.173-173, Article 173

2023

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Adipocyte Differentiation-Related Protein and OXPAT in Rat and Human Skeletal Muscle: Involvement in Lipid Accumulation and Type 2 Diabetes Mellitus

The journal of clinical endocrinology and metabolism, 2009-10, Vol.94 (10), p.4077-4085

2009

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Proton magnetic resonance spectroscopy reveals increased hepatic lipid content after a single high-fat meal with no additional modulation by added protein

The American journal of clinical nutrition, 2015, Vol.101 (1), p.65-71

2015

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PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans

Journal of lipid research, 2013-02, Vol.54 (2), p.522-534

2013

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Reduced skeletal muscle mitochondrial respiration and improved glucose metabolism in nondiabetic obese women during a very low calorie dietary intervention leading to rapid weight loss

Metabolism, clinical and experimental, 2009-08, Vol.58 (8), p.1145-1152

2009

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Reduced Incorporation of Fatty Acids Into Triacylglycerol in Myotubes From Obese Individuals With Type 2 Diabetes

Diabetes (New York, N.Y.), 2014-05, Vol.63 (5), p.1583-1593

2014

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Regulation of metabolic transcriptional co-activators and transcription factors with acute exercise

The FASEB journal, 2005-06, Vol.19 (8), p.986-988

2005

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ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity

Diabetologia, 2016-05, Vol.59 (5), p.1030-1039

2016

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Divergent remodeling of the skeletal muscle metabolome over 24 h between young, healthy men and older, metabolically compromised men

Cell reports (Cambridge), 2022-12, Vol.41 (11), p.111786-111786, Article 111786

2022

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Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus

Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle

Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy

Human skeletal muscle mitochondrial dynamics in relation to oxidative capacity and insulin sensitivity

Perilipin 2 Improves Insulin Sensitivity in Skeletal Muscle Despite Elevated Intramuscular Lipid Levels

Nine Months of Combined Training Improves Ex Vivo Skeletal Muscle Metabolism in Individuals With Type 2 Diabetes

Skeletal muscle mitochondrial network dynamics in metabolic disorders and aging

Long-echo time MR spectroscopy for skeletal muscle acetylcarnitine detection

Metabolic disturbances of non-alcoholic fatty liver resemble the alterations typical for type 2 diabetes

Evidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans

Mitochondrial dysfunction and lipotoxicity

High Oxidative Capacity Due to Chronic Exercise Training Attenuates Lipid-Induced Insulin Resistance

Intramyocellular lipid droplets and insulin sensitivity, the human perspective

The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria

Re-evaluating lipotoxic triggers in skeletal muscle: Relating intramyocellular lipid metabolism to insulin sensitivity

Effect of β2-agonist treatment on insulin-stimulated peripheral glucose disposal in healthy men in a randomised placebo-controlled trial

Adipocyte Differentiation-Related Protein and OXPAT in Rat and Human Skeletal Muscle: Involvement in Lipid Accumulation and Type 2 Diabetes Mellitus

Proton magnetic resonance spectroscopy reveals increased hepatic lipid content after a single high-fat meal with no additional modulation by added protein

PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans

Reduced skeletal muscle mitochondrial respiration and improved glucose metabolism in nondiabetic obese women during a very low calorie dietary intervention leading to rapid weight loss

Reduced Incorporation of Fatty Acids Into Triacylglycerol in Myotubes From Obese Individuals With Type 2 Diabetes

Regulation of metabolic transcriptional co-activators and transcription factors with acute exercise

ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity

Divergent remodeling of the skeletal muscle metabolome over 24 h between young, healthy men and older, metabolically compromised men

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