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Apelin inhibition prevents resistance and metastasis associated with anti‐angiogenic therapy

EMBO molecular medicine, 2019-08, Vol.11 (8), p.e9266-n/a

2019

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Downregulation of the Apelinergic Axis Accelerates Aging, whereas Its Systemic Restoration Improves the Mammalian Healthspan

Cell reports (Cambridge), 2017-11, Vol.21 (6), p.1471-1480

2017

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Elabela and Apelin actions in healthy and pathological pregnancies

Cytokine & growth factor reviews, 2019-04, Vol.46, p.45-53

2019

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Apelin expression deficiency in mice contributes to vascular stiffening by extracellular matrix remodeling of the aortic wall

Scientific reports, 2021-11, Vol.11 (1), p.22278-22278, Article 22278

2021

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Apelin protects against liver X receptor-mediated steatosis through AMPK and PPARα in human and mouse hepatocytes

Cellular signalling, 2017-11, Vol.39, p.84-94

2017

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Identification of essential genes for cancer immunotherapy

Nature (London), 2017-08, Vol.548 (7669), p.537

2017

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Apelin/APJ signaling suppresses the pressure ulcer formation in cutaneous ischemia-reperfusion injury mouse model

Scientific reports, 2020-01, Vol.10 (1), p.1349-1349, Article 1349

2020

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A metabolically stable apelin-17 analog decreases AVP-induced antidiuresis and improves hyponatremia

Nature communications, 2021-01, Vol.12 (1), p.305-14, Article 305

2021

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The G protein‐coupled receptor ligand apelin‐13 ameliorates skeletal muscle atrophy induced by chronic kidney disease

Journal of cachexia, sarcopenia and muscle, 2023-02, Vol.14 (1), p.553-564

2023

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Adipokine Apelin/APJ Pathway Promotes Peritoneal Dissemination of Ovarian Cancer Cells by Regulating Lipid Metabolism

Molecular cancer research, 2021-09, Vol.19 (9), p.1534-1545

2021

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Potential role of the apelin‐APJ pathway in sex‐related differential cardiotoxicity induced by doxorubicin in mice

Journal of applied toxicology, 2023-04, Vol.43 (4), p.557-576

2023

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Expression of Apelin and Apelin Receptor Protein in the Hypothalamo-Pituitary-Ovarian Axis during the Estrous Cycle of Mice

Neuroendocrinology, 2024-03, Vol.114 (3), p.234

2024

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Apelin receptor antagonist boosts dendritic cell vaccine efficacy in controlling angiogenic, metastatic and apoptotic-related factors in 4T1 breast tumor-bearing mice

Medical oncology (Northwood, London, England), 2023-05, Vol.40 (6), p.179-179, Article 179

2023

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Postnatal developmental expression and localization of apelin and apelin receptor protein in the ovary and uterus of mice

Molecular reproduction and development, 2023-01, Vol.90 (1), p.42-52

2023

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Angiotensin-Converting Enzyme 2 Metabolizes and Partially Inactivates Pyr-Apelin-13 and Apelin-17: Physiological Effects in the Cardiovascular System

Hypertension (Dallas, Tex. 1979), 2016-08, Vol.68 (2), p.365-377

2016

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An apelin receptor antagonist prevents pathological retinal angiogenesis with ischemic retinopathy in mice

Scientific reports, 2017-11, Vol.7 (1), p.15062-9, Article 15062

2017

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Expression and localization of apelin and its receptor in the testes of diabetic mice and its possible role in steroidogenesis

Cytokine (Philadelphia, Pa.), 2021-08, Vol.144, p.155554-155554, Article 155554

2021

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Cancer apelin receptor suppresses vascular mimicry in malignant melanoma

Pathology oncology research, 2023-01, Vol.29, p.1610867-1610867

2023

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Apelin and APJ orchestrate complex tissue-specific control of cardiomyocyte hypertrophy and contractility in the hypertrophy-heart failure transition

American journal of physiology. Heart and circulatory physiology, 2018-08, Vol.315 (2), p.H348-H356

2018

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Targeting APLN/APLNR Improves Antiangiogenic Efficiency and Blunts Proinvasive Side Effects of VEGFA/VEGFR2 Blockade in Glioblastoma

Cancer research (Chicago, Ill.), 2019-05, Vol.79 (9), p.2298-2313

2019

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The Apelin–Apelin Receptor Axis Triggers Cholangiocyte Proliferation and Liver Fibrosis During Mouse Models of Cholestasis

Hepatology (Baltimore, Md.), 2021-06, Vol.73 (6), p.2411-2428

2021

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Adipokine apelin ameliorates chronic colitis in Il-10−/− mice by promoting intestinal lymphatic functions

Biochemical pharmacology, 2018-02, Vol.148, p.202-212

2018

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Apelin receptor modulation mitigates letrozole-induced polycystic ovarian pathogenesis in mice

Cytokine (Philadelphia, Pa.), 2024-07, Vol.179, p.156639-156639, Article 156639

2024

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Maternal Inactivity Programs Skeletal Muscle Dysfunction in Offspring Mice by Attenuating Apelin Signaling and Mitochondrial Biogenesis

Cell reports (Cambridge), 2020-12, Vol.33 (9), p.108461-108461, Article 108461

2020

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Apelin Enhances Brown Adipogenesis and Browning of White Adipocytes

The Journal of biological chemistry, 2015-06, Vol.290 (23), p.14679-14691

2015

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Apelin inhibition prevents resistance and metastasis associated with anti‐angiogenic therapy

Downregulation of the Apelinergic Axis Accelerates Aging, whereas Its Systemic Restoration Improves the Mammalian Healthspan

Elabela and Apelin actions in healthy and pathological pregnancies

Apelin expression deficiency in mice contributes to vascular stiffening by extracellular matrix remodeling of the aortic wall

Apelin protects against liver X receptor-mediated steatosis through AMPK and PPARα in human and mouse hepatocytes

Identification of essential genes for cancer immunotherapy

Apelin/APJ signaling suppresses the pressure ulcer formation in cutaneous ischemia-reperfusion injury mouse model

A metabolically stable apelin-17 analog decreases AVP-induced antidiuresis and improves hyponatremia

The G protein‐coupled receptor ligand apelin‐13 ameliorates skeletal muscle atrophy induced by chronic kidney disease

Adipokine Apelin/APJ Pathway Promotes Peritoneal Dissemination of Ovarian Cancer Cells by Regulating Lipid Metabolism

Potential role of the apelin‐APJ pathway in sex‐related differential cardiotoxicity induced by doxorubicin in mice

Expression of Apelin and Apelin Receptor Protein in the Hypothalamo-Pituitary-Ovarian Axis during the Estrous Cycle of Mice

Apelin receptor antagonist boosts dendritic cell vaccine efficacy in controlling angiogenic, metastatic and apoptotic-related factors in 4T1 breast tumor-bearing mice

Postnatal developmental expression and localization of apelin and apelin receptor protein in the ovary and uterus of mice

Angiotensin-Converting Enzyme 2 Metabolizes and Partially Inactivates Pyr-Apelin-13 and Apelin-17: Physiological Effects in the Cardiovascular System

An apelin receptor antagonist prevents pathological retinal angiogenesis with ischemic retinopathy in mice

Expression and localization of apelin and its receptor in the testes of diabetic mice and its possible role in steroidogenesis

Cancer apelin receptor suppresses vascular mimicry in malignant melanoma

Apelin and APJ orchestrate complex tissue-specific control of cardiomyocyte hypertrophy and contractility in the hypertrophy-heart failure transition

Targeting APLN/APLNR Improves Antiangiogenic Efficiency and Blunts Proinvasive Side Effects of VEGFA/VEGFR2 Blockade in Glioblastoma

The Apelin–Apelin Receptor Axis Triggers Cholangiocyte Proliferation and Liver Fibrosis During Mouse Models of Cholestasis

Adipokine apelin ameliorates chronic colitis in Il-10−/− mice by promoting intestinal lymphatic functions

Apelin receptor modulation mitigates letrozole-induced polycystic ovarian pathogenesis in mice

Maternal Inactivity Programs Skeletal Muscle Dysfunction in Offspring Mice by Attenuating Apelin Signaling and Mitochondrial Biogenesis

Apelin Enhances Brown Adipogenesis and Browning of White Adipocytes

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