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Activation of autophagy protects against acetaminophen-induced hepatotoxicity

Hepatology (Baltimore, Md.), 2012-01, Vol.55 (1), p.222-232

2012

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Role and mechanisms of autophagy in acetaminophen‐induced liver injury

Liver international, 2018-08, Vol.38 (8), p.1363-1374

2018

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Receptor interacting protein kinase 3 is a critical early mediator of acetaminophen‐induced hepatocyte necrosis in mice

Hepatology (Baltimore, Md.), 2013-12, Vol.58 (6), p.2099-2108

2013

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An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis

Nature communications, 2020-07, Vol.11 (1), p.3612-16, Article 3612

2020

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Impaired TFEB-Mediated Lysosome Biogenesis and Autophagy Promote Chronic Ethanol-Induced Liver Injury and Steatosis in Mice

Gastroenterology (New York, N.Y. 1943), 2018-09, Vol.155 (3), p.865-879.e12

2018

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Curcumin attenuates isoniazid‐induced hepatotoxicity by upregulating the SIRT1/PGC‐1α/NRF1 pathway

Journal of applied toxicology, 2022-07, Vol.42 (7), p.1192-1204

2022

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Hepatocytic p62 suppresses ductular reaction and tumorigenesis in mouse livers with mTORC1 activation and defective autophagy

Journal of hepatology, 2022-03, Vol.76 (3), p.639-651

2022

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Loss of hepatic DRP1 exacerbates alcoholic hepatitis by inducing megamitochondria and mitochondrial maladaptation

Hepatology (Baltimore, Md.), 2023-01, Vol.77 (1), p.159-175

2023

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Critical Role of FoxO3a in Alcohol-Induced Autophagy and Hepatotoxicity

The American journal of pathology, 2013-12, Vol.183 (6), p.1815-1825

2013

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Parkin regulates mitophagy and mitochondrial function to protect against alcohol-induced liver injury and steatosis in mice

American journal of physiology: Gastrointestinal and liver physiology, 2015-09, Vol.309 (5), p.G324-G340

2015

Volltextzugriff (PDF)

Autophagy Reduces Acute Ethanol-Induced Hepatotoxicity and Steatosis in Mice

Gastroenterology (New York, N.Y. 1943), 2010-11, Vol.139 (5), p.1740-1752

2010

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Removal of Acetaminophen-Protein Adducts by Autophagy Protects Against Acetaminophen-Induced Liver Injury in Mice

Journal of hepatology, 2016-08, Vol.65 (2), p.354-362

2016

Volltextzugriff (PDF)

Trehalose activates hepatic transcription factor EB (TFEB) but fails to ameliorate alcohol‐impaired TFEB and liver injury in mice

Alcoholism, clinical and experimental research, 2021-10, Vol.45 (10), p.1950-1964

2021

Volltextzugriff (PDF)

Secretory Autophagy in Cancer-Associated Fibroblasts Promotes Head and Neck Cancer Progression and Offers a Novel Therapeutic Target

Cancer research (Chicago, Ill.), 2017-12, Vol.77 (23), p.6679-6691

2017

Volltextzugriff (PDF)

Methods for Monitoring Mitochondrial Biogenesis and Turnover in Cultured Hepatocytes and Mouse Liver Using MitoTimer Reporter Assay

Methods in molecular biology (Clifton, N.J.), 2023, Vol.2675, p.97

2023

Volltextzugriff (PDF)

Nix Is Critical to Two Distinct Phases of Mitophagy, Reactive Oxygen Species-mediated Autophagy Induction and Parkin-Ubiquitin-p62-mediated Mitochondrial Priming

The Journal of biological chemistry, 2010-09, Vol.285 (36), p.27879-27890

2010

Volltextzugriff (PDF)

KLF14/miR‐1283/TFAP2C axis inhibits HER2‐positive breast cancer progression via declining tumor cell proliferation

Molecular carcinogenesis, 2023-04, Vol.62 (4), p.532-545

2023

Volltextzugriff (PDF)

Glutamine synthetase limits β-catenin-mutated liver cancer growth by maintaining nitrogen homeostasis and suppressing mTORC1

The Journal of clinical investigation, 2022-12, Vol.132 (24), p.1-18

2022

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Mito-tempo protects against acute liver injury but induces limited secondary apoptosis during the late phase of acetaminophen hepatotoxicity

Archives of toxicology, 2019-01, Vol.93 (1), p.163-178

2019

Volltextzugriff (PDF)

Differential roles of unsaturated and saturated fatty acids on autophagy and apoptosis in hepatocytes

The Journal of pharmacology and experimental therapeutics, 2011-11, Vol.339 (2), p.487

2011

Volltextzugriff (PDF)

Receptor-Interacting Serine/Threonine-Protein Kinase 3 (RIPK3)–Mixed Lineage Kinase Domain-Like Protein (MLKL)–Mediated Necroptosis Contributes to Ischemia-Reperfusion Injury of Steatotic Livers

The American journal of pathology, 2019-07, Vol.189 (7), p.1363-1374

2019

Volltextzugriff (PDF)

VMP1 regulates hepatic lipoprotein secretion and NASH independent of autophagy

Autophagy, 2023-01, Vol.19 (1), p.367-369

2023

Volltextzugriff (PDF)

Loss of Hepatic Transcription Factor EB Attenuates Alcohol-Associated Liver Carcinogenesis

The American journal of pathology, 2022-01, Vol.192 (1), p.87-103

2022

Volltextzugriff (PDF)

Dissecting the dynamic turnover of GFP-LC3 in the autolysosome

Autophagy, 2011-02, Vol.7 (2), p.188-204

2011

Volltextzugriff (PDF)

The double-edged sword of MTOR in autophagy deficiency induced-liver injury and tumorigenesis

Autophagy, 2019-09, Vol.15 (9), p.1671-1673

2019

Volltextzugriff (PDF)

1 – 25 von 935

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Activation of autophagy protects against acetaminophen-induced hepatotoxicity

Role and mechanisms of autophagy in acetaminophen‐induced liver injury

Receptor interacting protein kinase 3 is a critical early mediator of acetaminophen‐induced hepatocyte necrosis in mice

An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis

Impaired TFEB-Mediated Lysosome Biogenesis and Autophagy Promote Chronic Ethanol-Induced Liver Injury and Steatosis in Mice

Curcumin attenuates isoniazid‐induced hepatotoxicity by upregulating the SIRT1/PGC‐1α/NRF1 pathway

Hepatocytic p62 suppresses ductular reaction and tumorigenesis in mouse livers with mTORC1 activation and defective autophagy

Loss of hepatic DRP1 exacerbates alcoholic hepatitis by inducing megamitochondria and mitochondrial maladaptation

Critical Role of FoxO3a in Alcohol-Induced Autophagy and Hepatotoxicity

Parkin regulates mitophagy and mitochondrial function to protect against alcohol-induced liver injury and steatosis in mice

Autophagy Reduces Acute Ethanol-Induced Hepatotoxicity and Steatosis in Mice

Removal of Acetaminophen-Protein Adducts by Autophagy Protects Against Acetaminophen-Induced Liver Injury in Mice

Trehalose activates hepatic transcription factor EB (TFEB) but fails to ameliorate alcohol‐impaired TFEB and liver injury in mice

Secretory Autophagy in Cancer-Associated Fibroblasts Promotes Head and Neck Cancer Progression and Offers a Novel Therapeutic Target

Methods for Monitoring Mitochondrial Biogenesis and Turnover in Cultured Hepatocytes and Mouse Liver Using MitoTimer Reporter Assay

Nix Is Critical to Two Distinct Phases of Mitophagy, Reactive Oxygen Species-mediated Autophagy Induction and Parkin-Ubiquitin-p62-mediated Mitochondrial Priming

KLF14/miR‐1283/TFAP2C axis inhibits HER2‐positive breast cancer progression via declining tumor cell proliferation

Glutamine synthetase limits β-catenin-mutated liver cancer growth by maintaining nitrogen homeostasis and suppressing mTORC1

Mito-tempo protects against acute liver injury but induces limited secondary apoptosis during the late phase of acetaminophen hepatotoxicity

Differential roles of unsaturated and saturated fatty acids on autophagy and apoptosis in hepatocytes

Receptor-Interacting Serine/Threonine-Protein Kinase 3 (RIPK3)–Mixed Lineage Kinase Domain-Like Protein (MLKL)–Mediated Necroptosis Contributes to Ischemia-Reperfusion Injury of Steatotic Livers

VMP1 regulates hepatic lipoprotein secretion and NASH independent of autophagy

Loss of Hepatic Transcription Factor EB Attenuates Alcohol-Associated Liver Carcinogenesis

Dissecting the dynamic turnover of GFP-LC3 in the autolysosome

The double-edged sword of MTOR in autophagy deficiency induced-liver injury and tumorigenesis

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