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Disruption of IRS-2 causes type 2 diabetes in mice

Nature (London), 1998-02, Vol.391 (6670), p.900-904

1998

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Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes

Genes & development, 2001-08, Vol.15 (15), p.1926-1934

2001

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Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver

Nature (London), 2001-02, Vol.409 (6821), p.729-733

2001

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Delivery of systemic chemotherapeutic agent to tumors by using focused ultrasound: study in a murine model

Radiology, 2005-02, Vol.234 (2), p.431-437

2005

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Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)

Science (American Association for the Advancement of Science), 2001-06, Vol.292 (5522), p.1728-1731

2001

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Increased Energy Expenditure, Decreased Adiposity, and Tissue-Specific Insulin Sensitivity in Protein-Tyrosine Phosphatase 1B-Deficient Mice

Molecular and Cellular Biology, 2000-08, Vol.20 (15), p.5479-5489

2000

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Glucose toxicity and the development of diabetes in mice with muscle-specific inactivation of GLUT4

The Journal of clinical investigation, 2001-07, Vol.108 (1), p.153-160

2001

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Tissue-Specific Overexpression of Lipoprotein Lipase Causes Tissue-Specific Insulin Resistance

Proceedings of the National Academy of Sciences - PNAS, 2001-06, Vol.98 (13), p.7522-7527

2001

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Uncoupling Protein-2 Negatively Regulates Insulin Secretion and Is a Major Link between Obesity, β Cell Dysfunction, and Type 2 Diabetes

Cell, 2001-06, Vol.105 (6), p.745-755

2001

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Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction

Molecular cell, 2000-07, Vol.6 (1), p.87-97

2000

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Mechanism of Insulin Resistance in A-ZIP/F-1 Fatless Mice

The Journal of biological chemistry, 2000-03, Vol.275 (12), p.8456-8460

2000

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Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice

The Journal of clinical investigation, 2000-02, Vol.105 (3), p.271-278

2000

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The Glycogen Shunt Maintains Glycolytic Homeostasis and the Warburg Effect in Cancer

Trends in Cancer, 2017-11, Vol.3 (11), p.761-767

2017

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Contrasting Effects of IRS-1 Versus IRS-2 Gene Disruption on Carbohydrate and Lipid Metabolism in Vivo

The Journal of biological chemistry, 2000-12, Vol.275 (50), p.38990-38994

2000

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Redistribution of substrates to adipose tissue promotes obesity in mice with selective insulin resistance in muscle

The Journal of clinical investigation, 2000-06, Vol.105 (12), p.1791-1797

2000

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Transgenic mice deficient in the LAR protein-tyrosine phosphatase exhibit profound defects in glucose homeostasis

Diabetes (New York, N.Y.), 1998-03, Vol.47 (3), p.493-497

1998

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In Vivo Effects of Uncoupling Protein-3 Gene Disruption on Mitochondrial Energy Metabolism

The Journal of biological chemistry, 2001-06, Vol.276 (23), p.20240-20244

2001

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Overexpression of the LAR (Leukocyte Antigen-Related) Protein-Tyrosine Phosphatase in Muscle Causes Insulin Resistance

Proceedings of the National Academy of Sciences - PNAS, 2001-04, Vol.98 (9), p.5187-5192

2001

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Overexpression of Glut4 protein in muscle increases basal and insulin-stimulated whole body glucose disposal in conscious mice

The Journal of clinical investigation, 1995-01, Vol.95 (1), p.429-432

1995

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Syntaxin 4 heterozygous knockout mice develop muscle insulin resistance

The Journal of clinical investigation, 2001-05, Vol.107 (10), p.1311-1318

2001

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A critical evaluation of mass isotopomer distribution analysis of gluconeogenesis in vivo

American journal of physiology: endocrinology and metabolism, 1999-07, Vol.277 (1), p.E154-E160

1999

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AMP Kinase Is Required for Mitochondrial Biogenesis in Skeletal Muscle in Response to Chronic Energy Deprivation

Proceedings of the National Academy of Sciences - PNAS, 2002-12, Vol.99 (25), p.15983-15987

2002

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Fish Oil Regulates Adiponectin Secretion by a Peroxisome Proliferator–Activated Receptor-γ–Dependent Mechanism in Mice

Diabetes (New York, N.Y.), 2006-04, Vol.55 (4), p.924-928

2006

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Disruption of Neural Signal Transducer and Activator of Transcription 3 Causes Obesity, Diabetes, Infertility, and Thermal Dysregulation

Proceedings of the National Academy of Sciences - PNAS, 2004-03, Vol.101 (13), p.4661-4666

2004

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Dual role of proapoptotic BAD in insulin secretion and beta cell survival

Nature medicine, 2008-02, Vol.14 (2), p.144-153

2008

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Disruption of IRS-2 causes type 2 diabetes in mice

Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes

Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver

Delivery of systemic chemotherapeutic agent to tumors by using focused ultrasound: study in a murine model

Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)

Increased Energy Expenditure, Decreased Adiposity, and Tissue-Specific Insulin Sensitivity in Protein-Tyrosine Phosphatase 1B-Deficient Mice

Glucose toxicity and the development of diabetes in mice with muscle-specific inactivation of GLUT4

Tissue-Specific Overexpression of Lipoprotein Lipase Causes Tissue-Specific Insulin Resistance

Uncoupling Protein-2 Negatively Regulates Insulin Secretion and Is a Major Link between Obesity, β Cell Dysfunction, and Type 2 Diabetes

Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction

Mechanism of Insulin Resistance in A-ZIP/F-1 Fatless Mice

Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice

The Glycogen Shunt Maintains Glycolytic Homeostasis and the Warburg Effect in Cancer

Contrasting Effects of IRS-1 Versus IRS-2 Gene Disruption on Carbohydrate and Lipid Metabolism in Vivo

Redistribution of substrates to adipose tissue promotes obesity in mice with selective insulin resistance in muscle

Transgenic mice deficient in the LAR protein-tyrosine phosphatase exhibit profound defects in glucose homeostasis

In Vivo Effects of Uncoupling Protein-3 Gene Disruption on Mitochondrial Energy Metabolism

Overexpression of the LAR (Leukocyte Antigen-Related) Protein-Tyrosine Phosphatase in Muscle Causes Insulin Resistance

Overexpression of Glut4 protein in muscle increases basal and insulin-stimulated whole body glucose disposal in conscious mice

Syntaxin 4 heterozygous knockout mice develop muscle insulin resistance

A critical evaluation of mass isotopomer distribution analysis of gluconeogenesis in vivo

AMP Kinase Is Required for Mitochondrial Biogenesis in Skeletal Muscle in Response to Chronic Energy Deprivation

Fish Oil Regulates Adiponectin Secretion by a Peroxisome Proliferator–Activated Receptor-γ–Dependent Mechanism in Mice

Disruption of Neural Signal Transducer and Activator of Transcription 3 Causes Obesity, Diabetes, Infertility, and Thermal Dysregulation

Dual role of proapoptotic BAD in insulin secretion and beta cell survival

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