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Apelin retards the progression of diabetic nephropathy

American journal of physiology. Renal physiology, 2013-03, Vol.304 (6), p.F788-F800

2013

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Proteolytic Processing of Angiopoietin-like Protein 4 by Proprotein Convertases Modulates Its Inhibitory Effects on Lipoprotein Lipase Activity

The Journal of biological chemistry, 2011-05, Vol.286 (18), p.15747-15756

2011

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PACE4 Undergoes an Oncogenic Alternative Splicing Switch in Cancer

Cancer research (Chicago, Ill.), 2017-12, Vol.77 (24), p.6863-6879

2017

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Efficacy of PACE4 pharmacotherapy in JHU-LNCaP-SM preclinical model of androgen independent prostate cancer

Scientific reports, 2022-10, Vol.12 (1), p.17489-17489, Article 17489

2022

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Cleavage of a Neuroinvasive Human Respiratory Virus Spike Glycoprotein by Proprotein Convertases Modulates Neurovirulence and Virus Spread within the Central Nervous System

PLoS pathogens, 2015-11, Vol.11 (11), p.e1005261-e1005261

2015

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Proprotein Convertase Subtilisin/Kexin Type 9 Deficiency Reduces Melanoma Metastasis in Liver

Neoplasia (New York, N.Y.), 2012-12, Vol.14 (12), p.1122-IN5

2012

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Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice

Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (43), p.17362-17367

2013

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Role of Proprotein Convertases in Prostate Cancer Progression

Neoplasia (New York, N.Y.), 2012-11, Vol.14 (11), p.1032-IN6

2012

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Molecular events in matrix protein metabolism in the aging kidney

Aging cell, 2012-12, Vol.11 (6), p.1065-1073

2012

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Corticosterone selectively targets endo-cortical surfaces by an osteoblast-dependent mechanism

Bone (New York, N.Y.), 2011-10, Vol.49 (4), p.733-742

2011

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Analysis of peptides in prohormone convertase 1/3 null mouse brain using quantitative peptidomics

Journal of neurochemistry, 2010-07, Vol.114 (1), p.215-225

2010

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Furin Is the Major Processing Enzyme of the Cardiac-specific Growth Factor Bone Morphogenetic Protein 10

The Journal of biological chemistry, 2011-07, Vol.286 (26), p.22785-22794

2011

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Targeting Host Cell Furin Proprotein Convertases as a Therapeutic Strategy against Bacterial Toxins and Viral Pathogens

The Journal of biological chemistry, 2007-07, Vol.282 (29), p.20847-20853

2007

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Disruption of Proprotein Convertase 1/3 (PC1/3) Expression in Mice Causes Innate Immune Defects and Uncontrolled Cytokine Secretion

The Journal of biological chemistry, 2012-04, Vol.287 (18), p.14703-14717

2012

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Chymase inhibitor-sensitive synthesis of endothelin-1 (1–31) by recombinant mouse mast cell protease 4 and human chymase

Biochemical pharmacology, 2015-03, Vol.94 (2), p.91-100

2015

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Structure design and manufacturing of layered bioceramic scaffolds for load-bearing bone reconstruction

Biomedical materials (Bristol), 2015-07, Vol.10 (4), p.045006-045006

2015

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Endogenous glucocorticoid signalling in osteoblasts is necessary to maintain normal bone structure in mice

Bone (New York, N.Y.), 2009-07, Vol.45 (1), p.61-67

2009

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Acute hyperglycemia rapidly stimulates VEGF mRNA translation in the kidney. Role of angiotensin type 2 receptor (AT2)

Cellular signalling, 2010-12, Vol.22 (12), p.1849-1857

2010

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PACE4-Based Molecular Targeting of Prostate Cancer Using an Engineered 64Cu-Radiolabeled Peptide Inhibitor

Neoplasia (New York, N.Y.), 2014-08, Vol.16 (8), p.634-643

2014

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Targeted Ablation of the Chromogranin A (Chga) Gene: Normal Neuroendocrine Dense-Core Secretory Granules and Increased Expression of Other Granins

Molecular endocrinology (Baltimore, Md.), 2006-08, Vol.20 (8), p.1935-1947

2006

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Biosynthesis of Proopiomelanocortin-Derived Peptides in Prohormone Convertase 2 and 7B2 Null Mice

Endocrinology (Philadelphia), 2004-02, Vol.145 (2), p.519-528

2004

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Identification and Characterization of Three Members of the Human Metallocarboxypeptidase Gene Family

The Journal of biological chemistry, 2002-04, Vol.277 (17), p.14954-14964

2002

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Mast Cell Degranulation Increases Mouse Mast Cell Protease 4-Dependent Vasopressor Responses to Big Endothelin-1 But Not Angiotensin I

The Journal of pharmacology and experimental therapeutics, 2021-02, Vol.376 (2), p.213-221

2021

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Cleavage of the V-ATPase associated prorenin receptor is mediated by PACE4 and is essential for growth of prostate cancer cells

PloS one, 2023-07, Vol.18 (7), p.e0288622-e0288622

2023

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Ser-Phosphorylation of PCSK9 (Proprotein Convertase Subtilisin-Kexin 9) by Fam20C (Family With Sequence Similarity 20, Member C) Kinase Enhances Its Ability to Degrade the LDLR (Low-Density Lipoprotein Receptor)

Arteriosclerosis, thrombosis, and vascular biology, 2019-10, Vol.39 (10), p.1996-2013

2019

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Apelin retards the progression of diabetic nephropathy

Proteolytic Processing of Angiopoietin-like Protein 4 by Proprotein Convertases Modulates Its Inhibitory Effects on Lipoprotein Lipase Activity

PACE4 Undergoes an Oncogenic Alternative Splicing Switch in Cancer

Efficacy of PACE4 pharmacotherapy in JHU-LNCaP-SM preclinical model of androgen independent prostate cancer

Cleavage of a Neuroinvasive Human Respiratory Virus Spike Glycoprotein by Proprotein Convertases Modulates Neurovirulence and Virus Spread within the Central Nervous System

Proprotein Convertase Subtilisin/Kexin Type 9 Deficiency Reduces Melanoma Metastasis in Liver

Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice

Role of Proprotein Convertases in Prostate Cancer Progression

Molecular events in matrix protein metabolism in the aging kidney

Corticosterone selectively targets endo-cortical surfaces by an osteoblast-dependent mechanism

Analysis of peptides in prohormone convertase 1/3 null mouse brain using quantitative peptidomics

Furin Is the Major Processing Enzyme of the Cardiac-specific Growth Factor Bone Morphogenetic Protein 10

Targeting Host Cell Furin Proprotein Convertases as a Therapeutic Strategy against Bacterial Toxins and Viral Pathogens

Disruption of Proprotein Convertase 1/3 (PC1/3) Expression in Mice Causes Innate Immune Defects and Uncontrolled Cytokine Secretion

Chymase inhibitor-sensitive synthesis of endothelin-1 (1–31) by recombinant mouse mast cell protease 4 and human chymase

Structure design and manufacturing of layered bioceramic scaffolds for load-bearing bone reconstruction

Endogenous glucocorticoid signalling in osteoblasts is necessary to maintain normal bone structure in mice

Acute hyperglycemia rapidly stimulates VEGF mRNA translation in the kidney. Role of angiotensin type 2 receptor (AT2)

PACE4-Based Molecular Targeting of Prostate Cancer Using an Engineered 64Cu-Radiolabeled Peptide Inhibitor

Targeted Ablation of the Chromogranin A (Chga) Gene: Normal Neuroendocrine Dense-Core Secretory Granules and Increased Expression of Other Granins

Biosynthesis of Proopiomelanocortin-Derived Peptides in Prohormone Convertase 2 and 7B2 Null Mice

Identification and Characterization of Three Members of the Human Metallocarboxypeptidase Gene Family

Mast Cell Degranulation Increases Mouse Mast Cell Protease 4-Dependent Vasopressor Responses to Big Endothelin-1 But Not Angiotensin I

Cleavage of the V-ATPase associated prorenin receptor is mediated by PACE4 and is essential for growth of prostate cancer cells

Ser-Phosphorylation of PCSK9 (Proprotein Convertase Subtilisin-Kexin 9) by Fam20C (Family With Sequence Similarity 20, Member C) Kinase Enhances Its Ability to Degrade the LDLR (Low-Density Lipoprotein Receptor)

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