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Genetic Otx2 mis-localization delays critical period plasticity across brain regions

Molecular psychiatry, 2017-05, Vol.22 (5), p.680-688

2017

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Otx genes are required for tissue specification in the developing eye

Development (Cambridge), 2001-06, Vol.128 (11), p.2019-2030

2001

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Craniofacial, vestibular and bone defects in mice lacking the Distal-less-related gene Dlx5

Development (Cambridge), 1999-09, Vol.126 (17), p.3795-3809

1999

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Increased dopaminergic innervation in the brain of conditional mutant mice overexpressing Otx2: Effects on locomotor behavior and seizure susceptibility

Neuroscience, 2014-03, Vol.261, p.173-183

2014

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The TINS Lecture : Understanding the roles of Otx1 and Otx2 in the control of brain morphogenesis

Trends in Neurosciences, 1999-03, Vol.22 (3), p.116-122

1999

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A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo

The EMBO journal, 1993-07, Vol.12 (7), p.2735-2747

1993

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Genetic control of brain morphogenesis through Otx gene dosage requirement

Development (Cambridge), 1997-09, Vol.124 (18), p.3639-3650

1997

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Progressive impairment of developing neuroendocrine cell lineages in the hypothalamus of mice lacking the Orthopedia gene

Genes & development, 1999-11, Vol.13 (21), p.2787-2800

1999

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Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2

Development (Cambridge), 2001-12, Vol.128 (23), p.4789-4800

2001

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Epilepsy and brain abnormalities in mice lacking the Otx1 gene

Nature genetics, 1996-10, Vol.14 (2), p.218-222

1996

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Visceral endoderm-restricted translation of Otx1 mediates recovery of Otx2 requirements for specification of anterior neural plate and normal gastrulation

Development (Cambridge), 1998-12, Vol.125 (24), p.5091-5104

1998

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Two vertebrate homeobox genes related to the Drosophila empty spiracles gene are expressed in the embryonic cerebral cortex

The EMBO journal, 1992-07, Vol.11 (7), p.2541-2550

1992

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Murine Otx1 and Drosophila otd genes share conserved genetic functions required in invertebrate and vertebrate brain development

Development (Cambridge), 1998-05, Vol.125 (9), p.1691-1702

1998

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Cloning and characterization of two members of the vertebrate Dlx gene family

Proceedings of the National Academy of Sciences - PNAS, 1994-03, Vol.91 (6), p.2250-2254

1994

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Otx Genes in Corticogenesis and Brain Development

Cerebral cortex (New York, N.Y. 1991), 1999-09, Vol.9 (6), p.533-542

1999

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Orthopedia Homeodomain Protein Is Essential for Diencephalic Dopaminergic Neuron Development

Current biology, 2007-05, Vol.17 (10), p.873-880

2007

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The role of Otx2 in organizing the anterior patterning in mouse

The International journal of developmental biology, 2001, Vol.45 (1), p.337

2001

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Graded Otx2 activities demonstrate dose-sensitive eye and retina phenotypes

Human molecular genetics, 2014-04, Vol.23 (7), p.1742-1753

2014

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Transient dwarfism and hypogonadism in mice lacking Otx1 reveal prepubescent stage-specific control of pituitary levels of GH, FSH and LH

Development (Cambridge), 1998-04, Vol.125 (7), p.1229-1239

1998

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Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain

Development (Cambridge), 2004-05, Vol.131 (9), p.2037-2048

2004

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OTD/OTX2 functional equivalence depends on 5' and 3' UTR-mediated control of Otx2 mRNA for nucleo-cytoplasmic export and epiblast-restricted translation

Development (Cambridge), 2001-12, Vol.128 (23), p.4801-4813

2001

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Forebrain and midbrain development requires epiblast-restricted Otx2 translational control mediated by its 3' UTR

Development (Cambridge), 2001-08, Vol.128 (15), p.2989-3000

2001

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Otx2 expression is restricted to dopaminergic neurons of the ventral tegmental area in the adult brain

The International journal of developmental biology, 2010, Vol.54 (5), p.939-945

2010

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The proto-oncogene RON is involved in development of epithelial, bone and neuro-endocrine tissues

Oncogene, 1995-12, Vol.11 (12), p.2627-2637

1995

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The role of Otx and Otp genes in brain development

The International journal of developmental biology, 2000, Vol.44 (6), p.669

2000

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Genetic Otx2 mis-localization delays critical period plasticity across brain regions

Otx genes are required for tissue specification in the developing eye

Craniofacial, vestibular and bone defects in mice lacking the Distal-less-related gene Dlx5

Increased dopaminergic innervation in the brain of conditional mutant mice overexpressing Otx2: Effects on locomotor behavior and seizure susceptibility

The TINS Lecture : Understanding the roles of Otx1 and Otx2 in the control of brain morphogenesis

A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo

Genetic control of brain morphogenesis through Otx gene dosage requirement

Progressive impairment of developing neuroendocrine cell lineages in the hypothalamus of mice lacking the Orthopedia gene

Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2

Epilepsy and brain abnormalities in mice lacking the Otx1 gene

Visceral endoderm-restricted translation of Otx1 mediates recovery of Otx2 requirements for specification of anterior neural plate and normal gastrulation

Two vertebrate homeobox genes related to the Drosophila empty spiracles gene are expressed in the embryonic cerebral cortex

Murine Otx1 and Drosophila otd genes share conserved genetic functions required in invertebrate and vertebrate brain development

Cloning and characterization of two members of the vertebrate Dlx gene family

Otx Genes in Corticogenesis and Brain Development

Orthopedia Homeodomain Protein Is Essential for Diencephalic Dopaminergic Neuron Development

The role of Otx2 in organizing the anterior patterning in mouse

Graded Otx2 activities demonstrate dose-sensitive eye and retina phenotypes

Transient dwarfism and hypogonadism in mice lacking Otx1 reveal prepubescent stage-specific control of pituitary levels of GH, FSH and LH

Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain

OTD/OTX2 functional equivalence depends on 5' and 3' UTR-mediated control of Otx2 mRNA for nucleo-cytoplasmic export and epiblast-restricted translation

Forebrain and midbrain development requires epiblast-restricted Otx2 translational control mediated by its 3' UTR

Otx2 expression is restricted to dopaminergic neurons of the ventral tegmental area in the adult brain

The proto-oncogene RON is involved in development of epithelial, bone and neuro-endocrine tissues

The role of Otx and Otp genes in brain development

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