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Bone Cancer Pain: From Model to Mechanism to Therapy

Journal of pain and symptom management, 2005-05, Vol.29 (5), p.32-46

2005

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Osteoprotegerin diminishes advanced bone cancer pain

Cancer research (Chicago, Ill.), 2001-05, Vol.61 (10), p.4038-4047

2001

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Simultaneous reduction in cancer pain, bone destruction, and tumor growth by selective inhibition of cyclooxygenase-2

Cancer research (Chicago, Ill.), 2002-12, Vol.62 (24), p.7343-7349

2002

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Different tumors in bone each give rise to a distinct pattern of skeletal destruction, bone cancer‐related pain behaviors and neurochemical changes in the central nervous system

International journal of cancer, 2003-05, Vol.104 (5), p.550-558

2003

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Bone cancer pain: the effects of the bisphosphonate alendronate on pain, skeletal remodeling, tumor growth and tumor necrosis

Pain (Amsterdam), 2004-09, Vol.111 (1), p.169-180

2004

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Efficacy of systemic morphine suggests a fundamental difference in the mechanisms that generate bone cancer vs. inflammatory pain

Pain (Amsterdam), 2002-10, Vol.99 (3), p.397-406

2002

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A phase 1 open-label, sequential dose-escalation study investigating the safety, tolerability, and pharmacokinetics of intravenous TLC388 administered to patients with advanced solid tumors

Investigational new drugs, 2014-06, Vol.32 (3), p.445-451

2014

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Two novel mutations in the MHC class II transactivator CIITA in a second patient from MHC class II deficiency complementation group A

Human genetics, 1997-04, Vol.99 (4), p.541-546

1997

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Cloning of the Major Histocompatibility Complex Class II Promoter Binding Protein Affected in a Hereditary Defect in Class II Gene Regulation

Proceedings of the National Academy of Sciences - PNAS, 1989-06, Vol.86 (11), p.4200-4204

1989

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A gene encoding a novel RFX-associated transactivator is mutated in the majority of MHC class II deficiency patients

Nature genetics, 1998-11, Vol.20 (3), p.273-277

1998

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Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)

Cell, 1993-10, Vol.75 (1), p.135-146

1993

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MHC Class II Regulation — Lessons from a Disease

The New England journal of medicine, 1995-01, Vol.332 (2), p.120-123

Mach, Bernard

1995

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A defect in the regulation of major histocompatibility complex class II gene expression in human HLA-DR negative lymphocytes from patients with combined immunodeficiency syndrome

The Journal of clinical investigation, 1985-07, Vol.76 (1), p.381-385

1985

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IDENTIFICATION OF HIV-INFECTED SERONEGATIVE INDIVIDUALS BY A DIRECT DIAGNOSTIC TEST BASED ON HYBRIDISATION TO AMPLIFIED VIRAL DNA

The Lancet (British edition), 1988-08, Vol.332 (8608), p.418-421

1988

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Mutation of RFXAP, a Regulator of MHC Class II Genes, in Primary MHC Class II Deficiency

The New England journal of medicine, 1997-09, Vol.337 (11), p.748-753

1997

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Replacement of HLA class II serology by the HLA‐DR microtitre plate oligotyping assay: a one‐year experience in unrelated bone marrow donor selection

British journal of haematology, 1993-10, Vol.85 (2), p.417-418

1993

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Bone marrow transplantation with unrelated donors : HLA class II oligonucleotide typing as predictive of mixed lymphocyte culture reactivity

Transplantation proceedings, 1993-02, Vol.25 (1), p.1243-1245

1993

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Oligonucleotide genotyping of HLA polymorphism on microtitre plates

The Lancet (British edition), 1992-10, Vol.340 (8824), p.870-873

1992

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Genetic and Molecular Definition of Complementation Group D in MHC Class II Deficiency

Human molecular genetics, 1998-05, Vol.7 (5), p.879-885

1998

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MHC class II-deficient combineds immunodeficiency : a disease of gene regulation: Genetic basis of primary immunodeficiencies

Immunological reviews, 1994, Vol.138, p.207-221

1994

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RB and A novel E2F‐1 binding protein in MHC class II deficient B‐cell lines and normal IFN‐γ induction of the class II transactivator ciita in class II non‐inducible RB‐defective tumor lines

International journal of cancer, 1995-08, Vol.62 (4), p.461-465

1995

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Antibodies to the nef protein and to nef peptides in HIV-1-infected seronegative individuals

AIDS research and human retroviruses, 1989-06, Vol.5 (3), p.279-291

1989

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Extensive study of DRB, DQA, and DQB gene polymorphism in 23 DR2-positive, insulin-dependent diabetes mellitus patients

Human immunology, 1992-02, Vol.33 (2), p.140-147

1992

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Zinc deficiency in exclusively breast-fed infants

Cutis (New York, N.Y.), 1998-04, Vol.61 (4), p.197

1998

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Absence of DRw15/3 and of DRw15/7 heterozygotes in Caucasian patients with systemic lupus erythemaosus

Tissue antigens, 1991, Vol.37 (1), p.10-15

1991

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Bone Cancer Pain: From Model to Mechanism to Therapy

Osteoprotegerin diminishes advanced bone cancer pain

Simultaneous reduction in cancer pain, bone destruction, and tumor growth by selective inhibition of cyclooxygenase-2

Different tumors in bone each give rise to a distinct pattern of skeletal destruction, bone cancer‐related pain behaviors and neurochemical changes in the central nervous system

Bone cancer pain: the effects of the bisphosphonate alendronate on pain, skeletal remodeling, tumor growth and tumor necrosis

Efficacy of systemic morphine suggests a fundamental difference in the mechanisms that generate bone cancer vs. inflammatory pain

A phase 1 open-label, sequential dose-escalation study investigating the safety, tolerability, and pharmacokinetics of intravenous TLC388 administered to patients with advanced solid tumors

Two novel mutations in the MHC class II transactivator CIITA in a second patient from MHC class II deficiency complementation group A

Cloning of the Major Histocompatibility Complex Class II Promoter Binding Protein Affected in a Hereditary Defect in Class II Gene Regulation

A gene encoding a novel RFX-associated transactivator is mutated in the majority of MHC class II deficiency patients

Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)

MHC Class II Regulation — Lessons from a Disease

A defect in the regulation of major histocompatibility complex class II gene expression in human HLA-DR negative lymphocytes from patients with combined immunodeficiency syndrome

IDENTIFICATION OF HIV-INFECTED SERONEGATIVE INDIVIDUALS BY A DIRECT DIAGNOSTIC TEST BASED ON HYBRIDISATION TO AMPLIFIED VIRAL DNA

Mutation of RFXAP, a Regulator of MHC Class II Genes, in Primary MHC Class II Deficiency

Replacement of HLA class II serology by the HLA‐DR microtitre plate oligotyping assay: a one‐year experience in unrelated bone marrow donor selection

Bone marrow transplantation with unrelated donors : HLA class II oligonucleotide typing as predictive of mixed lymphocyte culture reactivity

Oligonucleotide genotyping of HLA polymorphism on microtitre plates

Genetic and Molecular Definition of Complementation Group D in MHC Class II Deficiency

MHC class II-deficient combineds immunodeficiency : a disease of gene regulation: Genetic basis of primary immunodeficiencies

RB and A novel E2F‐1 binding protein in MHC class II deficient B‐cell lines and normal IFN‐γ induction of the class II transactivator ciita in class II non‐inducible RB‐defective tumor lines

Antibodies to the nef protein and to nef peptides in HIV-1-infected seronegative individuals

Extensive study of DRB, DQA, and DQB gene polymorphism in 23 DR2-positive, insulin-dependent diabetes mellitus patients

Zinc deficiency in exclusively breast-fed infants

Absence of DRw15/3 and of DRw15/7 heterozygotes in Caucasian patients with systemic lupus erythemaosus

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