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The RARγ Oncogene: An Achilles Heel for Some Cancers

International journal of molecular sciences, 2021-03, Vol.22 (7), p.3632

2021

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Suppression of MYC by PI3K/AKT/mTOR pathway inhibition in combination with all‐trans retinoic acid treatment for therapeutic gain in acute myeloid leukaemia

British journal of haematology, 2022-07, Vol.198 (2), p.338-348

2022

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New Strategies in Neuroblastoma: Therapeutic Targeting of MYCN and ALK

Clinical cancer research, 2013-11, Vol.19 (21), p.5814-5821

2013

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Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia

Nature medicine, 2012-04, Vol.18 (4), p.605-611

2012

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Differentiation therapy of acute myeloid leukemia: past, present and future

Current opinion in hematology, 2009-03, Vol.16 (2), p.84-91

2009

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Targeting Glutaminolysis Shows Efficacy in Both Prednisolone-Sensitive and in Metabolically Rewired Prednisolone-Resistant B-Cell Childhood Acute Lymphoblastic Leukaemia Cells

International journal of molecular sciences, 2023-02, Vol.24 (4), p.3378

2023

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Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

Nature genetics, 2005-04, Vol.37 (4), p.391-400

2005

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The acetyltransferase GCN5 maintains ATRA-resistance in non-APL AML

Leukemia, 2019-11, Vol.33 (11), p.2628-2639

2019

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The Protozoan Inhibitor Atovaquone Affects Mitochondrial Respiration and Shows In Vitro Efficacy Against Glucocorticoid-Resistant Cells in Childhood B-Cell Acute Lymphoblastic Leukaemia

Frontiers in oncology, 2021-03, Vol.11, p.632181-632181

2021

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Deregulated expression of HDAC9 in B cells promotes development of lymphoproliferative disease and lymphoma in mice

Disease models & mechanisms, 2016-12, Vol.9 (12), p.1483-1495

2016

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p53 Loss in MYC-Driven Neuroblastoma Leads to Metabolic Adaptations Supporting Radioresistance

Cancer research (Chicago, Ill.), 2016-05, Vol.76 (10), p.3025-3035

2016

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Semi-Quantitative Mass Spectrometry in AML Cells Identifies New Non-Genomic Targets of the EZH2 Methyltransferase

International journal of molecular sciences, 2017-07, Vol.18 (7), p.1440

2017

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A Case of AML Characterized by a Novel t(4;15)(q31;q22) Translocation That Confers a Growth-Stimulatory Response to Retinoid-Based Therapy

International journal of molecular sciences, 2017-07, Vol.18 (7), p.1492

2017

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The Histone Deacetylase 9 Gene Encodes Multiple Protein Isoforms

The Journal of biological chemistry, 2003-05, Vol.278 (18), p.16059-16072

2003

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DNA methylation-independent loss of RARA gene expression in acute myeloid leukemia

Blood, 2008-02, Vol.111 (4), p.2374-2377

2008

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Recruitment of the nuclear receptor corepressor N-CoR by the TEL moiety of the childhood leukemia–associated TEL-AML1 oncoprotein

Blood, 2000-10, Vol.96 (7), p.2557-2561

2000

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Neuroblastoma Arginase Activity Creates an Immunosuppressive Microenvironment That Impairs Autologous and Engineered Immunity

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15), p.3043-3053

2015

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Marked for death

Nature cell biology, 2008-05, Vol.10 (5), p.507-509

2008

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The biguanide polyamine analog verlindamycin promotes differentiation in neuroblastoma via induction of antizyme

Cancer gene therapy, 2022-07, Vol.29 (7), p.940-950

2022

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Selective Inhibition of SIN3 Corepressor with Avermectins as a Novel Therapeutic Strategy in Triple-Negative Breast Cancer

Molecular cancer therapeutics, 2015-08, Vol.14 (8), p.1824-1836

2015

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Retinoic acid receptor γ is a therapeutically targetable driver of growth and survival in prostate cancer

Cancer reports, 2020-12, Vol.3 (6), p.e1284-n/a

2020

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Cyclin-Dependent Kinase Inhibitor AT7519 as a Potential Drug for MYCN-Dependent Neuroblastoma

Clinical cancer research, 2015-11, Vol.21 (22), p.5100-5109

2015

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AML1/ETO, a promiscuous fusion oncoprotein

Blood, 2007-05, Vol.109 (10), p.4109-4110

2007

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Targeting of AML1-ETO in t(8;21) leukemia by oridonin generates a tumor suppressor-like protein

Science translational medicine, 2012-03, Vol.4 (127), p.127ra38

2012

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The RARγ Oncogene: An Achilles Heel for Some Cancers

Suppression of MYC by PI3K/AKT/mTOR pathway inhibition in combination with all‐trans retinoic acid treatment for therapeutic gain in acute myeloid leukaemia

New Strategies in Neuroblastoma: Therapeutic Targeting of MYCN and ALK

Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia

Differentiation therapy of acute myeloid leukemia: past, present and future

Targeting Glutaminolysis Shows Efficacy in Both Prednisolone-Sensitive and in Metabolically Rewired Prednisolone-Resistant B-Cell Childhood Acute Lymphoblastic Leukaemia Cells

Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

The acetyltransferase GCN5 maintains ATRA-resistance in non-APL AML

The Protozoan Inhibitor Atovaquone Affects Mitochondrial Respiration and Shows In Vitro Efficacy Against Glucocorticoid-Resistant Cells in Childhood B-Cell Acute Lymphoblastic Leukaemia

Deregulated expression of HDAC9 in B cells promotes development of lymphoproliferative disease and lymphoma in mice

p53 Loss in MYC-Driven Neuroblastoma Leads to Metabolic Adaptations Supporting Radioresistance

Semi-Quantitative Mass Spectrometry in AML Cells Identifies New Non-Genomic Targets of the EZH2 Methyltransferase

A Case of AML Characterized by a Novel t(4;15)(q31;q22) Translocation That Confers a Growth-Stimulatory Response to Retinoid-Based Therapy

The Histone Deacetylase 9 Gene Encodes Multiple Protein Isoforms

DNA methylation-independent loss of RARA gene expression in acute myeloid leukemia

Recruitment of the nuclear receptor corepressor N-CoR by the TEL moiety of the childhood leukemia–associated TEL-AML1 oncoprotein

Neuroblastoma Arginase Activity Creates an Immunosuppressive Microenvironment That Impairs Autologous and Engineered Immunity

Marked for death

Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease

The biguanide polyamine analog verlindamycin promotes differentiation in neuroblastoma via induction of antizyme

Selective Inhibition of SIN3 Corepressor with Avermectins as a Novel Therapeutic Strategy in Triple-Negative Breast Cancer

Retinoic acid receptor γ is a therapeutically targetable driver of growth and survival in prostate cancer

Cyclin-Dependent Kinase Inhibitor AT7519 as a Potential Drug for MYCN-Dependent Neuroblastoma

AML1/ETO, a promiscuous fusion oncoprotein

Targeting of AML1-ETO in t(8;21) leukemia by oridonin generates a tumor suppressor-like protein

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