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Pronounced proliferation of non-beta cells in response to beta-cell mitogens in isolated human islets of Langerhans

Scientific reports, 2021-05, Vol.11 (1), p.11283-11283, Article 11283

2021

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Lipopolysaccharides impair insulin gene expression in isolated islets of Langerhans via Toll-Like Receptor-4 and NF-κB signalling

PloS one, 2012-04, Vol.7 (4), p.e36200

2012

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Deletion of GPR40 Impairs Glucose-Induced Insulin Secretion In Vivo in Mice Without Affecting Intracellular Fuel Metabolism in Islets

Diabetes (New York, N.Y.), 2009-11, Vol.58 (11), p.2607-2615

2009

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A Call for Improved Reporting of Human Islet Characteristics in Research Articles

Diabetes (New York, N.Y.), 2019-02, Vol.68 (2), p.239-240

2019

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GPR40 Is Necessary but Not Sufficient for Fatty Acid Stimulation of Insulin Secretion In Vivo

Diabetes (New York, N.Y.), 2007-04, Vol.56 (4), p.1087-1094

2007

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Free fatty acid receptor 4 inhibitory signaling in delta cells regulates islet hormone secretion in mice

Molecular metabolism (Germany), 2021-03, Vol.45, p.101166-101166, Article 101166

2021

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Palmitate Inhibits Insulin Gene Expression by Altering PDX-1 Nuclear Localization and Reducing MafA Expression in Isolated Rat Islets of Langerhans

The Journal of biological chemistry, 2005-09, Vol.280 (37), p.32413-32418

2005

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The islet estrogen receptor-α is induced by hyperglycemia and protects against oxidative stress-induced insulin-deficient diabetes

PloS one, 2014-02, Vol.9 (2), p.e87941-e87941

2014

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Discovery of Novel Glucose-Regulated Proteins in Isolated Human Pancreatic Islets Using LC–MS/MS-Based Proteomics

Journal of proteome research, 2012-07, Vol.11 (7), p.3520-3532

2012

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PPAR-α–Null Mice Are Protected From High-Fat Diet–Induced Insulin Resistance

Diabetes (New York, N.Y.), 2001-12, Vol.50 (12), p.2809-2814

2001

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Adipose Triglyceride Lipase Is Implicated in Fuel- and Non-fuel-stimulated Insulin Secretion

The Journal of biological chemistry, 2009-06, Vol.284 (25), p.16848-16859

2009

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A Role for the Malonyl-CoA/Long-Chain Acyl-CoA Pathway of Lipid Signaling in the Regulation of Insulin Secretion in Response to Both Fuel and Nonfuel Stimuli

Diabetes (New York, N.Y.), 2004-04, Vol.53 (4), p.1007-1019

2004

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Cyclical and Alternating Infusions of Glucose and Intralipid in Rats Inhibit Insulin Gene Expression and Pdx-1 Binding in Islets

Diabetes (New York, N.Y.), 2008-02, Vol.57 (2), p.424-431

2008

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Antecedent Hyperglycemia, Not Hyperlipidemia, Is Associated With Increased Islet Triacylglycerol Content and Decreased Insulin Gene mRNA Level in Zucker Diabetic Fatty Rats

Diabetes (New York, N.Y.), 2001-11, Vol.50 (11), p.2481-2486

2001

Volltextzugriff (PDF)

Evidence Against the Involvement of Oxidative Stress in Fatty Acid Inhibition of Insulin Secretion

Diabetes (New York, N.Y.), 2004-10, Vol.53 (10), p.2610-2616

2004

Volltextzugriff (PDF)

Differential Effects of Hyperlipidemia on Insulin Secretion in Islets of Langerhans From Hyperglycemic Versus Normoglycemic Rats

Diabetes (New York, N.Y.), 2002-03, Vol.51 (3), p.662-668

2002

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Single-Cell RNA Sequencing Reveals a Role for Reactive Oxygen Species and Peroxiredoxins in Fatty Acid-Induced Rat β-Cell Proliferation

Diabetes (New York, N.Y.), 2023-01, Vol.72 (1), p.45-58

2023

Volltextzugriff (PDF)

Binding of activating transcription factor 6 to the A5/Core of the rat insulin II gene promoter does not mediate its transcriptional repression

Journal of molecular endocrinology, 2011-12, Vol.47 (3), p.273-283

2011

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Phospholipid hydrolysis and insulin secretion: a step toward solving the Rubik's cube

American journal of physiology: endocrinology and metabolism, 2008-02, Vol.294 (2), p.E214-E216

Poitout, Vincent

2008

Volltextzugriff (PDF)

The ΔF508 Mutation in the Cystic Fibrosis Transmembrane Conductance Regulator Is Associated With Progressive Insulin Resistance and Decreased Functional β-Cell Mass in Mice

Diabetes (New York, N.Y.), 2015-12, Vol.64 (12), p.4112-4122

2015

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Urea impairs β cell glycolysis and insulin secretion in chronic kidney disease

The Journal of clinical investigation, 2016-09, Vol.126 (9), p.3598-3612

2016

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HB-EGF Signaling Is Required for Glucose-Induced Pancreatic β-Cell Proliferation in Rats

Diabetes (New York, N.Y.), 2020-03, Vol.69 (3), p.369-380

2020

Volltextzugriff (PDF)

Regulation of the Insulin Gene by Glucose and Fatty Acids

The Journal of nutrition, 2006-04, Vol.136 (4), p.873-876

2006

Volltextzugriff (PDF)

β-Cell Lipotoxicity: Burning Fat into Heat?

Endocrinology (Philadelphia), 2004-08, Vol.145 (8), p.3563-3565

Poitout, Vincent

2004

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The P21-activated kinase PAK4 is implicated in fatty-acid potentiation of insulin secretion downstream of free fatty acid receptor 1

Islets, 2016-11, Vol.8 (6), p.157-164

2016

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Pronounced proliferation of non-beta cells in response to beta-cell mitogens in isolated human islets of Langerhans

Lipopolysaccharides impair insulin gene expression in isolated islets of Langerhans via Toll-Like Receptor-4 and NF-κB signalling

Deletion of GPR40 Impairs Glucose-Induced Insulin Secretion In Vivo in Mice Without Affecting Intracellular Fuel Metabolism in Islets

A Call for Improved Reporting of Human Islet Characteristics in Research Articles

GPR40 Is Necessary but Not Sufficient for Fatty Acid Stimulation of Insulin Secretion In Vivo

Free fatty acid receptor 4 inhibitory signaling in delta cells regulates islet hormone secretion in mice

Palmitate Inhibits Insulin Gene Expression by Altering PDX-1 Nuclear Localization and Reducing MafA Expression in Isolated Rat Islets of Langerhans

The islet estrogen receptor-α is induced by hyperglycemia and protects against oxidative stress-induced insulin-deficient diabetes

Discovery of Novel Glucose-Regulated Proteins in Isolated Human Pancreatic Islets Using LC–MS/MS-Based Proteomics

PPAR-α–Null Mice Are Protected From High-Fat Diet–Induced Insulin Resistance

Adipose Triglyceride Lipase Is Implicated in Fuel- and Non-fuel-stimulated Insulin Secretion

A Role for the Malonyl-CoA/Long-Chain Acyl-CoA Pathway of Lipid Signaling in the Regulation of Insulin Secretion in Response to Both Fuel and Nonfuel Stimuli

Cyclical and Alternating Infusions of Glucose and Intralipid in Rats Inhibit Insulin Gene Expression and Pdx-1 Binding in Islets

Antecedent Hyperglycemia, Not Hyperlipidemia, Is Associated With Increased Islet Triacylglycerol Content and Decreased Insulin Gene mRNA Level in Zucker Diabetic Fatty Rats

Evidence Against the Involvement of Oxidative Stress in Fatty Acid Inhibition of Insulin Secretion

Differential Effects of Hyperlipidemia on Insulin Secretion in Islets of Langerhans From Hyperglycemic Versus Normoglycemic Rats

Single-Cell RNA Sequencing Reveals a Role for Reactive Oxygen Species and Peroxiredoxins in Fatty Acid-Induced Rat β-Cell Proliferation

Binding of activating transcription factor 6 to the A5/Core of the rat insulin II gene promoter does not mediate its transcriptional repression

Phospholipid hydrolysis and insulin secretion: a step toward solving the Rubik's cube

The ΔF508 Mutation in the Cystic Fibrosis Transmembrane Conductance Regulator Is Associated With Progressive Insulin Resistance and Decreased Functional β-Cell Mass in Mice

Urea impairs β cell glycolysis and insulin secretion in chronic kidney disease

HB-EGF Signaling Is Required for Glucose-Induced Pancreatic β-Cell Proliferation in Rats

Regulation of the Insulin Gene by Glucose and Fatty Acids

β-Cell Lipotoxicity: Burning Fat into Heat?

The P21-activated kinase PAK4 is implicated in fatty-acid potentiation of insulin secretion downstream of free fatty acid receptor 1

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