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Predicting a Drug’s Membrane Permeability: A Computational Model Validated With in Vitro Permeability Assay Data

The journal of physical chemistry. B, 2017-05, Vol.121 (20), p.5228-5237

2017

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Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice

Science translational medicine, 2015-07, Vol.7 (298), p.298ra117

2015

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Use of Accelerator Mass Spectrometry in Human Health and Molecular Toxicology

Chemical research in toxicology, 2016-12, Vol.29 (12), p.1976-1986

2016

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Correlation of Platinum Cytotoxicity to Drug-DNA Adduct Levels in a Breast Cancer Cell Line Panel

Chemical research in toxicology, 2018-12, Vol.31 (12), p.1293-1304

2018

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Toward Predicting Acute Myeloid Leukemia Patient Response to 7 + 3 Induction Chemotherapy via Diagnostic Microdosing

Chemical research in toxicology, 2018-10, Vol.31 (10), p.1042-1051

2018

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Mass Spectrometric Characterization of an Acid-Labile Adduct Formed with 2‑Amino-1-methyl-6-phenylimidazo[4,5‑b]pyridine and Albumin in Humans

Chemical research in toxicology, 2017-02, Vol.30 (2), p.705-714

2017

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Disposition of the Dietary Mutagen 2‑Amino-3,8-dimethylimidazo[4,5‑f]quinoxaline in Healthy and Pancreatic Cancer Compromised Humans

Chemical research in toxicology, 2016-03, Vol.29 (3), p.352-358

2016

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Diagnostic Microdosing Approach to Study Gemcitabine Resistance

Chemical research in toxicology, 2016-11, Vol.29 (11), p.1843-1848

2016

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Molecular Dissection of Induced Platinum Resistance through Functional and Gene Expression Analysis in a Cell Culture Model of Bladder Cancer

PloS one, 2016-01, Vol.11 (1), p.e0146256

2016

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The urinary metabolite profile of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is predictive of colon dna adducts after a low-dose exposure in humans

Cancer research (Chicago, Ill.), 2006-11, Vol.66 (21), p.10541-10547

2006

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N-Glucuronidation of 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) and N-hydroxy-PhIP by specific human UDP-glucuronosyltransferases

Carcinogenesis (New York), 2001-07, Vol.22 (7), p.1087-1093

2001

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Human UDP-Glucuronosyltransferase 1A1 Is the Primary Enzyme Responsible for the N-Glucuronidation of N-Hydroxy-PhIP in Vitro

Chemical research in toxicology, 2004-08, Vol.17 (8), p.1137-1144

2004

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A microdosing approach for characterizing formation and repair of carboplatin–DNA monoadducts and chemoresistance

International journal of cancer, 2011-09, Vol.129 (6), p.1425-1434

2011

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DNA isolation and sample preparation for quantification of adduct levels by accelerator mass spectrometry

Methods in molecular biology (Clifton, N.J.), 2014, Vol.1105, p.147

2014

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A Comprehensive Investigation of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) Metabolism in the Mouse Using a Multivariate Data Analysis Approach

Chemical research in toxicology, 2007-03, Vol.20 (3), p.531-542

2007

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What Do Diet-Induced Changes in Phase I and II Enzymes Tell Us about Prevention from Exposure to Heterocyclic Amines?

The Journal of nutrition, 2006-10, Vol.136 (10), p.2683S-2684S

2006

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The identification of [2-14C]2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine metabolites in humans

Carcinogenesis (New York), 1999-04, Vol.20 (4), p.705-713

1999

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Human exposure to heterocyclic amine food mutagens/carcinogens: Relevance to breast cancer

Environmental and molecular mutagenesis, 2002, Vol.39 (2-3), p.112-118

2002

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Identification of urine metabolites of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine following consumption of a single cooked chicken meal in humans

Carcinogenesis (New York), 2000-11, Vol.21 (11), p.2065-2072

2000

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Impact of environmental exposures on the mutagenicity/carcinogenicity of heterocyclic amines

Toxicology (Amsterdam), 2004-05, Vol.198 (1), p.135-145

2004

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Macromolecular adduct formation and metabolism of heterocyclic amines in humans and rodents at low doses

Cancer letters, 1999-09, Vol.143 (2), p.149-155

1999

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Distribution and metabolism of [14C]-resveratrol in human prostate tissue after oral administration of a “dietary-achievable” or “pharmacological” dose: what are the implications for anticancer activity?

The American journal of clinical nutrition, 2021-05, Vol.113 (5), p.1115-1125

2021

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Oxaliplatin-DNA Adducts as Predictive Biomarkers of FOLFOX Response in Colorectal Cancer: A Potential Treatment Optimization Strategy

Molecular cancer therapeutics, 2020-04, Vol.19 (4), p.1070-1079

2020

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COX-2/sEH Dual Inhibitor PTUPB Potentiates the Antitumor Efficacy of Cisplatin

Molecular cancer therapeutics, 2018-02, Vol.17 (2), p.474-483

2018

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Paclitaxel Enhances Carboplatin-DNA Adduct Formation and Cytotoxicity

Chemical research in toxicology, 2015-12, Vol.28 (12), p.2250-2252

2015

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Predicting a Drug’s Membrane Permeability: A Computational Model Validated With in Vitro Permeability Assay Data

Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice

Use of Accelerator Mass Spectrometry in Human Health and Molecular Toxicology

Correlation of Platinum Cytotoxicity to Drug-DNA Adduct Levels in a Breast Cancer Cell Line Panel

Toward Predicting Acute Myeloid Leukemia Patient Response to 7 + 3 Induction Chemotherapy via Diagnostic Microdosing

Mass Spectrometric Characterization of an Acid-Labile Adduct Formed with 2‑Amino-1-methyl-6-phenylimidazo[4,5‑b]pyridine and Albumin in Humans

Disposition of the Dietary Mutagen 2‑Amino-3,8-dimethylimidazo[4,5‑f]quinoxaline in Healthy and Pancreatic Cancer Compromised Humans

Diagnostic Microdosing Approach to Study Gemcitabine Resistance

Molecular Dissection of Induced Platinum Resistance through Functional and Gene Expression Analysis in a Cell Culture Model of Bladder Cancer

The urinary metabolite profile of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is predictive of colon dna adducts after a low-dose exposure in humans

N-Glucuronidation of 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) and N-hydroxy-PhIP by specific human UDP-glucuronosyltransferases

Human UDP-Glucuronosyltransferase 1A1 Is the Primary Enzyme Responsible for the N-Glucuronidation of N-Hydroxy-PhIP in Vitro

A microdosing approach for characterizing formation and repair of carboplatin–DNA monoadducts and chemoresistance

DNA isolation and sample preparation for quantification of adduct levels by accelerator mass spectrometry

A Comprehensive Investigation of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) Metabolism in the Mouse Using a Multivariate Data Analysis Approach

What Do Diet-Induced Changes in Phase I and II Enzymes Tell Us about Prevention from Exposure to Heterocyclic Amines?

The identification of [2-14C]2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine metabolites in humans

Human exposure to heterocyclic amine food mutagens/carcinogens: Relevance to breast cancer

Identification of urine metabolites of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine following consumption of a single cooked chicken meal in humans

Impact of environmental exposures on the mutagenicity/carcinogenicity of heterocyclic amines

Macromolecular adduct formation and metabolism of heterocyclic amines in humans and rodents at low doses

Distribution and metabolism of [14C]-resveratrol in human prostate tissue after oral administration of a “dietary-achievable” or “pharmacological” dose: what are the implications for anticancer activity?

Oxaliplatin-DNA Adducts as Predictive Biomarkers of FOLFOX Response in Colorectal Cancer: A Potential Treatment Optimization Strategy

COX-2/sEH Dual Inhibitor PTUPB Potentiates the Antitumor Efficacy of Cisplatin

Paclitaxel Enhances Carboplatin-DNA Adduct Formation and Cytotoxicity

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