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The promise of γδ T cells and the γδ T cell receptor for cancer immunotherapy

Cellular & molecular immunology, 2015-11, Vol.12 (6), p.656-668

2015

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Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactions

Nature communications, 2019-02, Vol.10 (1), p.741-741, Article 741

2019

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Allosteric activation of T cell antigen receptor signaling by quaternary structure relaxation

Cell reports (Cambridge), 2021-07, Vol.36 (2), p.109375-109375, Article 109375

2021

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Germ Line-governed Recognition of a Cancer Epitope by an Immunodominant Human T-cell Receptor

The Journal of biological chemistry, 2009-10, Vol.284 (40), p.27281-27289

2009

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Different T Cell Receptor Affinity Thresholds and CD8 Coreceptor Dependence Govern Cytotoxic T Lymphocyte Activation and Tetramer Binding Properties

The Journal of biological chemistry, 2007-08, Vol.282 (33), p.23799-23810

2007

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Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig

PLoS pathogens, 2018-05, Vol.14 (5), p.e1007017-e1007017

2018

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Human TCR-Binding Affinity is Governed by MHC Class Restriction

Journal of Immunology, 2007-05, Vol.178 (9), p.5727-5734

2007

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Peptide length determines the outcome of TCR/peptide-MHCI engagement

Blood, 2013-02, Vol.121 (7), p.1112-1123

2013

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The molecular determinants of CD8 co‐receptor function

Immunology, 2012-10, Vol.137 (2), p.139-148

2012

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Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA

The Journal of clinical investigation, 2020-05, Vol.130 (5), p.2673-2688

2020

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CD4+ T Cells Recognize Conserved Influenza A Epitopes through Shared Patterns of V-Gene Usage and Complementary Biochemical Features

Cell reports (Cambridge), 2020-07, Vol.32 (2), p.107885-107885, Article 107885

2020

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Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection

PLoS pathogens, 2010-11, Vol.6 (11), p.e1001198-e1001198

2010

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Peptide Super-Agonist Enhances T-Cell Responses to Melanoma

Frontiers in immunology, 2019-03, Vol.10, p.319-319

2019

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VDJdb in 2019: database extension, new analysis infrastructure and a T-cell receptor motif compendium

Nucleic acids research, 2020-01, Vol.48 (D1), p.D1057-D1062

2020

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Targeting the T cell receptor β-chain constant region for immunotherapy of T cell malignancies

Nature medicine, 2017-12, Vol.23 (12), p.1416-1423

2017

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The multiple roles of the CD8 coreceptor in T cell biology: opportunities for the selective modulation of self-reactive cytotoxic T cells

Journal of leukocyte biology, 2011-12, Vol.90 (6), p.1089-1099

2011

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Engineering soluble T‐cell receptors for therapy

The FEBS journal, 2021-11, Vol.288 (21), p.6159-6173

2021

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Correlation of in situ mechanosensitive responses of the Moraxella catarrhalis adhesin UspA1 with fibronectin and receptor CEACAM1 binding

Proceedings of the National Academy of Sciences - PNAS, 2011-09, Vol.108 (37), p.15174-15178

2011

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Peptide-Major Histocompatibility Complex Dimensions Control Proximal Kinase-Phosphatase Balance during T Cell Activation

The Journal of biological chemistry, 2009-09, Vol.284 (38), p.26096-26105

2009

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Dual role of the peptide-loading complex as proofreader and limiter of MHC-I presentation

Proceedings of the National Academy of Sciences - PNAS, 2024-05, Vol.121 (22), p.e2321600121

2024

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Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity

The Journal of clinical investigation, 2016-06, Vol.126 (6), p.2191-2204

2016

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Reliable In Silico Ranking of Engineered Therapeutic TCR Binding Affinities with MMPB/GBSA

Journal of chemical information and modeling, 2022-02, Vol.62 (3), p.577-590

2022

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The ultimate mix and match: making sense of HLA alleles and peptide repertoires

Immunology and cell biology, 2015-07, Vol.93 (6), p.515-516

Cole, David K

2015

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Tuning the potency and selectivity of ImmTAC molecules by affinity modulation

Clinical and experimental immunology, 2024-02, Vol.215 (2), p.105-119

2024

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Molecular characterization of HLA class II binding to the LAG‐3 T cell co‐inhibitory receptor

European journal of immunology, 2021-02, Vol.51 (2), p.331-341

2021

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The promise of γδ T cells and the γδ T cell receptor for cancer immunotherapy

Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactions

Allosteric activation of T cell antigen receptor signaling by quaternary structure relaxation

Germ Line-governed Recognition of a Cancer Epitope by an Immunodominant Human T-cell Receptor

Different T Cell Receptor Affinity Thresholds and CD8 Coreceptor Dependence Govern Cytotoxic T Lymphocyte Activation and Tetramer Binding Properties

Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig

Human TCR-Binding Affinity is Governed by MHC Class Restriction

Peptide length determines the outcome of TCR/peptide-MHCI engagement

The molecular determinants of CD8 co‐receptor function

Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA

CD4+ T Cells Recognize Conserved Influenza A Epitopes through Shared Patterns of V-Gene Usage and Complementary Biochemical Features

Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection

Peptide Super-Agonist Enhances T-Cell Responses to Melanoma

VDJdb in 2019: database extension, new analysis infrastructure and a T-cell receptor motif compendium

Targeting the T cell receptor β-chain constant region for immunotherapy of T cell malignancies

The multiple roles of the CD8 coreceptor in T cell biology: opportunities for the selective modulation of self-reactive cytotoxic T cells

Engineering soluble T‐cell receptors for therapy

Correlation of in situ mechanosensitive responses of the Moraxella catarrhalis adhesin UspA1 with fibronectin and receptor CEACAM1 binding

Peptide-Major Histocompatibility Complex Dimensions Control Proximal Kinase-Phosphatase Balance during T Cell Activation

Dual role of the peptide-loading complex as proofreader and limiter of MHC-I presentation

Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity

Reliable In Silico Ranking of Engineered Therapeutic TCR Binding Affinities with MMPB/GBSA

The ultimate mix and match: making sense of HLA alleles and peptide repertoires

Tuning the potency and selectivity of ImmTAC molecules by affinity modulation

Molecular characterization of HLA class II binding to the LAG‐3 T cell co‐inhibitory receptor

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