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Glutamate transporters have a chloride channel with two hydrophobic gates

Nature (London), 2021-03, Vol.591 (7849), p.327-331

2021

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Balanced Multielectrolyte Solution versus Saline in Critically Ill Adults

The New England journal of medicine, 2022-03, Vol.386 (9), p.815-826

2022

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VX-445–Tezacaftor–Ivacaftor in Patients with Cystic Fibrosis and One or Two Phe508del Alleles

The New England journal of medicine, 2018-10, Vol.379 (17), p.1612-1620

2018

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Evaluation of skin sensitization induced by four ionic liquids

Journal of applied toxicology, 2022-03, Vol.42 (3), p.392-408

2022

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Triple Therapy for Cystic Fibrosis Phe508del–Gating and –Residual Function Genotypes

The New England journal of medicine, 2021-08, Vol.385 (9), p.815-825

2021

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A gain-of-function mutation in the CLCN2 chloride channel gene causes primary aldosteronism

Nature genetics, 2018-03, Vol.50 (3), p.355-361

2018

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Maintenance fluid therapy and fluid creep impose more significant fluid, sodium, and chloride burdens than resuscitation fluids in critically ill patients: a retrospective study in a tertiary mixed ICU population

Intensive care medicine, 2018-04, Vol.44 (4), p.409-417

2018

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0.9% saline versus Plasma-Lyte as initial fluid in children with diabetic ketoacidosis (SPinK trial): a double-blind randomized controlled trial

Critical care (London, England), 2020-01, Vol.24 (1), p.1-1, Article 1

2020

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Real‐world data confirm elexacftor/tezacaftor/ivacaftor modulators halves sweat chloride concentration in eligible people with cystic fibrosis

APMIS : acta pathologica, microbiologica et immunologica Scandinavica, 2024-10, Vol.132 (10), p.728-733

2024

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Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial

The Lancet (British edition), 2019-11, Vol.394 (10212), p.1940-1948

2019

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Association between intravenous chloride load during resuscitation and in-hospital mortality among patients with SIRS

Intensive care medicine, 2014-12, Vol.40 (12), p.1897-1905

2014

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Elevated aldosterone and blood pressure in a mouse model of familial hyperaldosteronism with ClC-2 mutation

Nature communications, 2019-11, Vol.10 (1), p.5155-14, Article 5155

2019

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The influence of hydration status on ion transport in the rabbit (Oryctolagus cuniculus) skin-An in vitro study

PloS one, 2021-08, Vol.16 (8), p.e0255825-e0255825

2021

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VX-659–Tezacaftor–Ivacaftor in Patients with Cystic Fibrosis and One or Two Phe508del Alleles

The New England journal of medicine, 2018-10, Vol.379 (17), p.1599-1611

2018

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Electroneutral Na + /Cl - cotransport activity of zebrafish Slc12a10.1 expressed in Xenopus oocytes

American journal of physiology. Regulatory, integrative and comparative physiology, 2024-08, Vol.327 (2), p.R152-R163

2024

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CLCN2 chloride channel mutations in familial hyperaldosteronism type II

Nature genetics, 2018-03, Vol.50 (3), p.349-354

2018

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Activation of ClC‐3 chloride channel by 17β‐estradiol relies on the estrogen receptor α expression in breast cancer

Journal of cellular physiology, 2018-02, Vol.233 (2), p.1071-1081

2018

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Evidence for Two Subpopulations of Cerebrospinal Fluid-Contacting Neurons with Opposite GABAergic Signaling in Adult Mouse Spinal Cord

The Journal of neuroscience, 2024-05, Vol.44 (22), p.e2289222024

2024

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Elexacaftor–Tezacaftor–Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele

The New England journal of medicine, 2019-11, Vol.381 (19), p.1809-1819

2019

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Drinking Water Sodium and Elevated Blood Pressure of Healthy Pregnant Women in Salinity-Affected Coastal Areas

Hypertension (Dallas, Tex. 1979), 2016-08, Vol.68 (2), p.464-470

2016

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High sodium intake increases blood pressure and risk of kidney disease. From the Science of Salt: A regularly updated systematic review of salt and health outcomes (August 2016 to March 2017)

The journal of clinical hypertension (Greenwich, Conn.), 2018-12, Vol.20 (12), p.1654-1665

2018

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Safety, pharmacokinetics, and pharmacodynamics of ivacaftor in patients aged 2–5 years with cystic fibrosis and a CFTR gating mutation (KIWI): an open-label, single-arm study

The lancet respiratory medicine, 2016-02, Vol.4 (2), p.107-115

2016

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In vivo and in vitro ivacaftor response in cystic fibrosis patients with residual CFTR function: N‐of‐1 studies

Pediatric pulmonology, 2017-04, Vol.52 (4), p.472-479

2017

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Plasma-Lyte 148 vs 0.9% saline for fluid resuscitation in diabetic ketoacidosis

Journal of critical care, 2012-04, Vol.27 (2), p.138-145

2012

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Effect of Salt Substitution on Cardiovascular Events and Death

The New England journal of medicine, 2021-09, Vol.385 (12), p.1067-1077

2021

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Glutamate transporters have a chloride channel with two hydrophobic gates

Balanced Multielectrolyte Solution versus Saline in Critically Ill Adults

VX-445–Tezacaftor–Ivacaftor in Patients with Cystic Fibrosis and One or Two Phe508del Alleles

Evaluation of skin sensitization induced by four ionic liquids

Triple Therapy for Cystic Fibrosis Phe508del–Gating and –Residual Function Genotypes

A gain-of-function mutation in the CLCN2 chloride channel gene causes primary aldosteronism

Maintenance fluid therapy and fluid creep impose more significant fluid, sodium, and chloride burdens than resuscitation fluids in critically ill patients: a retrospective study in a tertiary mixed ICU population

0.9% saline versus Plasma-Lyte as initial fluid in children with diabetic ketoacidosis (SPinK trial): a double-blind randomized controlled trial

Real‐world data confirm elexacftor/tezacaftor/ivacaftor modulators halves sweat chloride concentration in eligible people with cystic fibrosis

Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial

Association between intravenous chloride load during resuscitation and in-hospital mortality among patients with SIRS

Elevated aldosterone and blood pressure in a mouse model of familial hyperaldosteronism with ClC-2 mutation

The influence of hydration status on ion transport in the rabbit (Oryctolagus cuniculus) skin-An in vitro study

VX-659–Tezacaftor–Ivacaftor in Patients with Cystic Fibrosis and One or Two Phe508del Alleles

Electroneutral Na + /Cl - cotransport activity of zebrafish Slc12a10.1 expressed in Xenopus oocytes

CLCN2 chloride channel mutations in familial hyperaldosteronism type II

Activation of ClC‐3 chloride channel by 17β‐estradiol relies on the estrogen receptor α expression in breast cancer

Evidence for Two Subpopulations of Cerebrospinal Fluid-Contacting Neurons with Opposite GABAergic Signaling in Adult Mouse Spinal Cord

Elexacaftor–Tezacaftor–Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele

Drinking Water Sodium and Elevated Blood Pressure of Healthy Pregnant Women in Salinity-Affected Coastal Areas

High sodium intake increases blood pressure and risk of kidney disease. From the Science of Salt: A regularly updated systematic review of salt and health outcomes (August 2016 to March 2017)

Safety, pharmacokinetics, and pharmacodynamics of ivacaftor in patients aged 2–5 years with cystic fibrosis and a CFTR gating mutation (KIWI): an open-label, single-arm study

In vivo and in vitro ivacaftor response in cystic fibrosis patients with residual CFTR function: N‐of‐1 studies

Plasma-Lyte 148 vs 0.9% saline for fluid resuscitation in diabetic ketoacidosis

Effect of Salt Substitution on Cardiovascular Events and Death

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