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Fatty Acids and Insulin Secretion: From FFAR and Near?

Diabetes (New York, N.Y.), 2018-10, Vol.67 (10), p.1932-1934

Poitout, Vincent

2018

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Targeting lipid GPCRs to treat type 2 diabetes mellitus - progress and challenges

Nature reviews. Endocrinology, 2021-03, Vol.17 (3), p.162-175

2021

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The fatty acid receptor FFA1/GPR40 a decade later: how much do we know?

Trends in endocrinology and metabolism, 2013-08, Vol.24 (8), p.398-407

2013

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β-Cell Glucose Toxicity, Lipotoxicity, and Chronic Oxidative Stress in Type 2 Diabetes

Diabetes (New York, N.Y.), 2004-02, Vol.53 (suppl 1), p.S119-S124

2004

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Lack of TXNIP Protects Against Mitochondria-Mediated Apoptosis but Not Against Fatty Acid–Induced ER Stress–Mediated β-Cell Death

Diabetes (New York, N.Y.), 2010-02, Vol.59 (2), p.440-447

2010

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Considerations and guidelines for mouse metabolic phenotyping in diabetes research

Diabetologia, 2018-03, Vol.61 (3), p.526-538

2018

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Glucose and fatty acids synergistically and reversibly promote beta cell proliferation in rats

Diabetologia, 2017-05, Vol.60 (5), p.879-888

2017

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Deletion of GPR40 Impairs Glucose-Induced Insulin Secretion In Vivo in Mice Without Affecting Intracellular Fuel Metabolism in Islets

Diabetes (New York, N.Y.), 2009-11, Vol.58 (11), p.2607-2615

2009

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The Fatty Acid Receptor GPR40 Plays a Role in Insulin Secretion In Vivo After High-Fat Feeding

Diabetes (New York, N.Y.), 2008-09, Vol.57 (9), p.2432-2437

2008

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A Call for Improved Reporting of Human Islet Characteristics in Research Articles

Diabetes (New York, N.Y.), 2019-02, Vol.68 (2), p.239-240

2019

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GPR40 Is Necessary but Not Sufficient for Fatty Acid Stimulation of Insulin Secretion In Vivo

Diabetes (New York, N.Y.), 2007-04, Vol.56 (4), p.1087-1094

2007

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Free fatty acid receptor 4 inhibitory signaling in delta cells regulates islet hormone secretion in mice

Molecular metabolism (Germany), 2021-03, Vol.45, p.101166-101166, Article 101166

2021

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Editorial: Pancreas Imaging Across the Spectrum

Frontiers in endocrinology (Lausanne), 2021-01, Vol.12, p.832519-832519

2021

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Defective insulin secretory response to intravenous glucose in C57Bl/6J compared to C57Bl/6N mice

Molecular metabolism (Germany), 2014-12, Vol.3 (9), p.848-854

2014

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PGC-1 coactivators in β-cells regulate lipid metabolism and are essential for insulin secretion coupled to fatty acids

Molecular metabolism (Germany), 2015-11, Vol.4 (11), p.811-822

2015

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Lipotoxicity of the Pancreatic β-Cell Is Associated With Glucose-Dependent Esterification of Fatty Acids Into Neutral Lipids

Diabetes (New York, N.Y.), 2001-02, Vol.50 (2), p.315-321

2001

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CMPF: A Biomarker for Type 2 Diabetes Mellitus Progression?

Trends in endocrinology and metabolism, 2016-07, Vol.27 (7), p.439-440

2016

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The regulator of G-protein signaling RGS16 promotes insulin secretion and β-cell proliferation in rodent and human islets

Molecular metabolism (Germany), 2016-10, Vol.5 (10), p.988-996

2016

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PPAR-α–Null Mice Are Protected From High-Fat Diet–Induced Insulin Resistance

Diabetes (New York, N.Y.), 2001-12, Vol.50 (12), p.2809-2814

2001

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A Role for the Malonyl-CoA/Long-Chain Acyl-CoA Pathway of Lipid Signaling in the Regulation of Insulin Secretion in Response to Both Fuel and Nonfuel Stimuli

Diabetes (New York, N.Y.), 2004-04, Vol.53 (4), p.1007-1019

2004

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Glucolipotoxicity: Fuel Excess and β-Cell Dysfunction

Endocrine reviews, 2008-05, Vol.29 (3), p.351-366

2008

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Involvement of Per-Arnt-Sim Kinase and Extracellular-Regulated Kinases-1/2 in Palmitate Inhibition of Insulin Gene Expression in Pancreatic β-Cells

Diabetes (New York, N.Y.), 2009-09, Vol.58 (9), p.2048-2058

2009

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Cyclical and Alternating Infusions of Glucose and Intralipid in Rats Inhibit Insulin Gene Expression and Pdx-1 Binding in Islets

Diabetes (New York, N.Y.), 2008-02, Vol.57 (2), p.424-431

2008

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Antecedent Hyperglycemia, Not Hyperlipidemia, Is Associated With Increased Islet Triacylglycerol Content and Decreased Insulin Gene mRNA Level in Zucker Diabetic Fatty Rats

Diabetes (New York, N.Y.), 2001-11, Vol.50 (11), p.2481-2486

2001

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Evidence Against the Involvement of Oxidative Stress in Fatty Acid Inhibition of Insulin Secretion

Diabetes (New York, N.Y.), 2004-10, Vol.53 (10), p.2610-2616

2004

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Fatty Acids and Insulin Secretion: From FFAR and Near?

Targeting lipid GPCRs to treat type 2 diabetes mellitus - progress and challenges

The fatty acid receptor FFA1/GPR40 a decade later: how much do we know?

β-Cell Glucose Toxicity, Lipotoxicity, and Chronic Oxidative Stress in Type 2 Diabetes

Lack of TXNIP Protects Against Mitochondria-Mediated Apoptosis but Not Against Fatty Acid–Induced ER Stress–Mediated β-Cell Death

Considerations and guidelines for mouse metabolic phenotyping in diabetes research

Glucose and fatty acids synergistically and reversibly promote beta cell proliferation in rats

Deletion of GPR40 Impairs Glucose-Induced Insulin Secretion In Vivo in Mice Without Affecting Intracellular Fuel Metabolism in Islets

The Fatty Acid Receptor GPR40 Plays a Role in Insulin Secretion In Vivo After High-Fat Feeding

A Call for Improved Reporting of Human Islet Characteristics in Research Articles

GPR40 Is Necessary but Not Sufficient for Fatty Acid Stimulation of Insulin Secretion In Vivo

Free fatty acid receptor 4 inhibitory signaling in delta cells regulates islet hormone secretion in mice

Editorial: Pancreas Imaging Across the Spectrum

Defective insulin secretory response to intravenous glucose in C57Bl/6J compared to C57Bl/6N mice

PGC-1 coactivators in β-cells regulate lipid metabolism and are essential for insulin secretion coupled to fatty acids

Lipotoxicity of the Pancreatic β-Cell Is Associated With Glucose-Dependent Esterification of Fatty Acids Into Neutral Lipids

CMPF: A Biomarker for Type 2 Diabetes Mellitus Progression?

The regulator of G-protein signaling RGS16 promotes insulin secretion and β-cell proliferation in rodent and human islets

PPAR-α–Null Mice Are Protected From High-Fat Diet–Induced Insulin Resistance

A Role for the Malonyl-CoA/Long-Chain Acyl-CoA Pathway of Lipid Signaling in the Regulation of Insulin Secretion in Response to Both Fuel and Nonfuel Stimuli

Glucolipotoxicity: Fuel Excess and β-Cell Dysfunction

Involvement of Per-Arnt-Sim Kinase and Extracellular-Regulated Kinases-1/2 in Palmitate Inhibition of Insulin Gene Expression in Pancreatic β-Cells

Cyclical and Alternating Infusions of Glucose and Intralipid in Rats Inhibit Insulin Gene Expression and Pdx-1 Binding in Islets

Antecedent Hyperglycemia, Not Hyperlipidemia, Is Associated With Increased Islet Triacylglycerol Content and Decreased Insulin Gene mRNA Level in Zucker Diabetic Fatty Rats

Evidence Against the Involvement of Oxidative Stress in Fatty Acid Inhibition of Insulin Secretion

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