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Mutations and epimutations in the origin of cancer

Experimental cell research, 2012-02, Vol.318 (4), p.299-310

Peltomaeki, Paeivi

2012

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Ten Years After Mutation Testing for Lynch Syndrome: Cancer Incidence and Outcome in Mutation-Positive and Mutation-Negative Family Members

Journal of clinical oncology, 2009-10, Vol.27 (28), p.4793-4797

2009

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Gene fusions and oncogenic mutations in MLH1 deficient and BRAFV600E wild-type colorectal cancers

Virchows Archiv : an international journal of pathology, 2022-04, Vol.480 (4), p.807-817

2022

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Epigenetic signatures of familial cancer are characteristic of tumor type and family category

Cancer research (Chicago, Ill.), 2008-06, Vol.68 (12), p.4597-4605

2008

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BRAF mutation in sporadic colorectal cancer and Lynch syndrome

Virchows Archiv : an international journal of pathology, 2013-11, Vol.463 (5), p.613-621

2013

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MicroRNA Methylation in Colorectal Cancer

Advances in experimental medicine and biology, 2016, Vol.937, p.109-122

2016

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p53 Codon 72 and MDM2 SNP309 Polymorphisms and Age of Colorectal Cancer Onset in Lynch Syndrome

Clinical cancer research, 2005-10, Vol.11 (19), p.6840-6844

2005

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Altered methylation at microRNA-associated CpG islands in hereditary and sporadic carcinomas: a methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA)-based approach

Molecular medicine (Cambridge, Mass.), 2011-07, Vol.17 (7-8), p.726-735

2011

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Immunoprofiles and DNA Methylation of Inflammatory Marker Genes in Ulcerative Colitis-Associated Colorectal Tumorigenesis

Biomolecules (Basel, Switzerland), 2021-09, Vol.11 (10), p.1440

2021

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Mitotic abnormalities precede microsatellite instability in lynch syndrome-associated colorectal tumourigenesis

EBioMedicine, 2024-05, Vol.103, p.105111-105111, Article 105111

2024

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Patterns of PIK3CA alterations in familial colorectal and endometrial carcinoma

International journal of cancer, 2007-08, Vol.121 (4), p.915-920

2007

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Genetic and Epigenetic Modification of MLH1 Accounts for a Major Share of Microsatellite-Unstable Colorectal Cancers

The American journal of pathology, 2000-05, Vol.156 (5), p.1773-1779

2000

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Loss of Imprinting of the Insulin-Like Growth Factor II Gene Occurs by Biallelic Methylation in a Core Region of H19-Associated CTCF-binding Sites in Colorectal Cancer

Proceedings of the National Academy of Sciences - PNAS, 2001-01, Vol.98 (2), p.591-596

2001

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PTEN Mutational Spectra, Expression Levels, and Subcellular Localization in Microsatellite Stable and Unstable Colorectal Cancers

The American journal of pathology, 2002-08, Vol.161 (2), p.439-447

2002

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Distinct Genetic and Epigenetic Signatures of Colorectal Cancers According to Ethnic Origin

Cancer epidemiology, biomarkers & prevention, 2012, Vol.21 (1), p.202-211

2012

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3'-UTR Poly(T/U) Tract Deletions and Altered Expression of EWSR1 Are a Hallmark of Mismatch Repair―Deficient Cancers

Cancer research (Chicago, Ill.), 2014, Vol.74 (1), p.224-234

2014

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Comprehensive characterization of HNPCC-related colorectal cancers reveals striking molecular features in families with no germline mismatch repair gene mutations

Oncogene, 2005-02, Vol.24 (9), p.1542-1551

2005

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The role of hPMS1 and hPMS2 in predisposing to colorectal cancer

Cancer research (Chicago, Ill.), 2001-11, Vol.61 (21), p.7798-7802

2001

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Lynch syndrome and related familial colorectal cancers

Critical reviews in oncogenesis, 2008, Vol.14 (1), p.1-22

2008

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Endometrial and Colorectal Tumors from Patients with Hereditary Nonpolyposis Colon Cancer Display Different Patterns of Microsatellite Instability

The American journal of pathology, 2002-06, Vol.160 (6), p.1953-1958

2002

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Somatic FGF9 mutations in colorectal and endometrial carcinomas associated with membranous β-catenin

Human mutation, 2008-03, Vol.29 (3), p.390-397

2008

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Epigenetic Phenotypes Distinguish Microsatellite-Stable and -Unstable Colorectal Cancers

Proceedings of the National Academy of Sciences - PNAS, 1999-10, Vol.96 (22), p.12661-12666

1999

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Mutations associated with HNPCC predisposition -- Update of ICG-HNPCC/INSiGHT mutation database

Disease markers, 2004, Vol.20 (4-5), p.269-276

2004

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Identification of DHX40 as a candidate susceptibility gene for colorectal and hematological neoplasia

Leukemia, 2023-11, Vol.37 (11), p.2301-2305

2023

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Deletion of 1p loci and microsatellite instability in colorectal polyps

Genes chromosomes & cancer, 1995-11, Vol.14 (3), p.182-188

1995

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Mutations and epimutations in the origin of cancer

Ten Years After Mutation Testing for Lynch Syndrome: Cancer Incidence and Outcome in Mutation-Positive and Mutation-Negative Family Members

Gene fusions and oncogenic mutations in MLH1 deficient and BRAFV600E wild-type colorectal cancers

Epigenetic signatures of familial cancer are characteristic of tumor type and family category

BRAF mutation in sporadic colorectal cancer and Lynch syndrome

MicroRNA Methylation in Colorectal Cancer

p53 Codon 72 and MDM2 SNP309 Polymorphisms and Age of Colorectal Cancer Onset in Lynch Syndrome

Altered methylation at microRNA-associated CpG islands in hereditary and sporadic carcinomas: a methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA)-based approach

Immunoprofiles and DNA Methylation of Inflammatory Marker Genes in Ulcerative Colitis-Associated Colorectal Tumorigenesis

Mitotic abnormalities precede microsatellite instability in lynch syndrome-associated colorectal tumourigenesis

Patterns of PIK3CA alterations in familial colorectal and endometrial carcinoma

Genetic and Epigenetic Modification of MLH1 Accounts for a Major Share of Microsatellite-Unstable Colorectal Cancers

Loss of Imprinting of the Insulin-Like Growth Factor II Gene Occurs by Biallelic Methylation in a Core Region of H19-Associated CTCF-binding Sites in Colorectal Cancer

PTEN Mutational Spectra, Expression Levels, and Subcellular Localization in Microsatellite Stable and Unstable Colorectal Cancers

Distinct Genetic and Epigenetic Signatures of Colorectal Cancers According to Ethnic Origin

3'-UTR Poly(T/U) Tract Deletions and Altered Expression of EWSR1 Are a Hallmark of Mismatch Repair―Deficient Cancers

Comprehensive characterization of HNPCC-related colorectal cancers reveals striking molecular features in families with no germline mismatch repair gene mutations

The role of hPMS1 and hPMS2 in predisposing to colorectal cancer

Lynch syndrome and related familial colorectal cancers

Endometrial and Colorectal Tumors from Patients with Hereditary Nonpolyposis Colon Cancer Display Different Patterns of Microsatellite Instability

Somatic FGF9 mutations in colorectal and endometrial carcinomas associated with membranous β-catenin

Epigenetic Phenotypes Distinguish Microsatellite-Stable and -Unstable Colorectal Cancers

Mutations associated with HNPCC predisposition -- Update of ICG-HNPCC/INSiGHT mutation database

Identification of DHX40 as a candidate susceptibility gene for colorectal and hematological neoplasia

Deletion of 1p loci and microsatellite instability in colorectal polyps

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