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Identification of N-(1H-pyrazol-4-yl)carboxamide inhibitors of interleukin-1 receptor associated kinase 4: Bicyclic core modifications

Bioorganic & medicinal chemistry letters, 2015-11, Vol.25 (22), p.5384-5388

2015

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Studies toward the total synthesis of phalarine: a survey of some biomimetic possibilities

Tetrahedron letters, 2006-07, Vol.47 (28), p.4839-4841

2006

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Piperazinyl pyrimidine derivatives as potent γ-secretase modulators

Bioorganic & medicinal chemistry letters, 2010-02, Vol.20 (3), p.1269-1271

2010

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Purine derivatives as potent γ-secretase modulators

Bioorganic & medicinal chemistry letters, 2010-04, Vol.20 (7), p.2279-2282

2010

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Lead optimization of 4,4-biaryl piperidine amides as γ-secretase inhibitors

Bioorganic & medicinal chemistry letters, 2012-05, Vol.22 (9), p.3203-3207

2012

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Metal Catalyzed Synthesis of Dihydropyridobenzodiazepines

Organometallics, 2019-01, Vol.38 (1), p.81-84

2019

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From Chiral Resolution to Diastereoselective Ellman Chemistry to Biocatalysis: Route Evolution for the Efficient Synthesis of the Tetrahydrobenzoazepine Core of BTK Inhibitor BIIB091

Organic process research & development, 2023-08, Vol.27 (8), p.1463-1473

2023

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Rapid construction of imidazopyridines from ortho-haloaminopyridines

Tetrahedron letters, 2016-06, Vol.57 (25), p.2708-2712

2016

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Exploring Chemical Diversity of Epoxyquinoid Natural Products: Synthesis and Biological Activity of (−)-Jesterone and Related Molecules

Organic letters, 2001-05, Vol.3 (11), p.1649-1652

2001

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A practical strategy for the synthesis of 2-dialkylamino-4-arylamino-6-aminopyrimidines

Tetrahedron letters, 2009-10, Vol.50 (43), p.5888-5893

2009

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Synthesis of Epoxyquinol A and Related Molecules: Probing Chemical Reactivity of Epoxyquinol Dimers and 2H-Pyran Precursors

Journal of organic chemistry, 2005-07, Vol.70 (15), p.6053-6065

2005

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Sulfone Displacement Approach for Large-Scale Synthesis of 4‑Chloro‑N‑(1-methyl‑1H‑pyrazol-4-yl)pyrimidin-2-amine

Organic process research & development, 2022-01, Vol.26 (1), p.137-143

2022

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Process Development and Large-Scale Synthesis of BTK Inhibitor BIIB068

Organic process research & development, 2020-06, Vol.24 (6), p.1199-1206

2020

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Discovery and optimization of heteroaryl piperazines as potent and selective PI3Kδ inhibitors

Bioorganic & medicinal chemistry letters, 2020-01, Vol.30 (1), p.126715, Article 126715

2020

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Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation

Bioorganic & medicinal chemistry letters, 2017-06, Vol.27 (12), p.2721-2726

2017

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Process Safety Considerations for the Supply of a High-Energy Oxadiazole IDO1-Selective Inhibitor

Organic process research & development, 2019-06, Vol.23 (6), p.1178-1190

2019

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Potent benzoazepinone γ-secretase modulators with improved bioavailability

Bioorganic & medicinal chemistry letters, 2015-09, Vol.25 (17), p.3495-3500

2015

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Studies directed toward the synthesis of the guanidine alkaloid, spiroleucettadine: some observations at the level of structure

Tetrahedron letters, 2006-01, Vol.47 (3), p.385-387

2006

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Angiogenesis Inhibitor Epoxyquinol A: Total Synthesis and Inhibition of Transcription Factor NF-κB

Organic letters, 2002-09, Vol.4 (19), p.3267-3270

2002

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Studies toward the synthesis of torreyanic acid and related epoxyquinoid natural products

Li, Chaomin

2005

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Identification of N-(1H-pyrazol-4-yl)carboxamide inhibitors of interleukin-1 receptor associated kinase 4: Bicyclic core modifications

Studies toward the total synthesis of phalarine: a survey of some biomimetic possibilities

Piperazinyl pyrimidine derivatives as potent γ-secretase modulators

Purine derivatives as potent γ-secretase modulators

Lead optimization of 4,4-biaryl piperidine amides as γ-secretase inhibitors

Metal Catalyzed Synthesis of Dihydropyridobenzodiazepines

From Chiral Resolution to Diastereoselective Ellman Chemistry to Biocatalysis: Route Evolution for the Efficient Synthesis of the Tetrahydrobenzoazepine Core of BTK Inhibitor BIIB091

Rapid construction of imidazopyridines from ortho-haloaminopyridines

Exploring Chemical Diversity of Epoxyquinoid Natural Products: Synthesis and Biological Activity of (−)-Jesterone and Related Molecules

A practical strategy for the synthesis of 2-dialkylamino-4-arylamino-6-aminopyrimidines

Synthesis of Epoxyquinol A and Related Molecules: Probing Chemical Reactivity of Epoxyquinol Dimers and 2H-Pyran Precursors

Sulfone Displacement Approach for Large-Scale Synthesis of 4‑Chloro‑N‑(1-methyl‑1H‑pyrazol-4-yl)pyrimidin-2-amine

Process Development and Large-Scale Synthesis of BTK Inhibitor BIIB068

Discovery and optimization of heteroaryl piperazines as potent and selective PI3Kδ inhibitors

Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation

Process Safety Considerations for the Supply of a High-Energy Oxadiazole IDO1-Selective Inhibitor

Potent benzoazepinone γ-secretase modulators with improved bioavailability

Studies directed toward the synthesis of the guanidine alkaloid, spiroleucettadine: some observations at the level of structure

Angiogenesis Inhibitor Epoxyquinol A: Total Synthesis and Inhibition of Transcription Factor NF-κB

Studies toward the synthesis of torreyanic acid and related epoxyquinoid natural products

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