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Persistent cAMP-signals triggered by internalized G-protein-coupled receptors

PLoS biology, 2009-08, Vol.7 (8), p.e1000172

2009

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Experimental and mathematical analysis of cAMP nanodomains

PloS one, 2017-04, Vol.12 (4), p.e0174856

2017

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Sweet taste receptor expressed in pancreatic beta-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion

PloS one, 2009-04, Vol.4 (4), p.e5106-e5106

2009

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Analysis of receptor oligomerization by FRAP microscopy

Nature methods, 2009-03, Vol.6 (3), p.225-230

2009

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Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2

Nature, 2003-12, Vol.426 (6966), p.574-579

2003

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Novel Single Chain cAMP Sensors for Receptor-induced Signal Propagation

The Journal of biological chemistry, 2004-09, Vol.279 (36), p.37215-37218

2004

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Role of membrane microdomains in compartmentation of cAMP signaling

PloS one, 2014-04, Vol.9 (4), p.e95835-e95835

2014

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Dynamics of receptor/G protein coupling in living cells

The EMBO journal, 2005-12, Vol.24 (23), p.4106-4114

2005

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Measurement of the millisecond activation switch of G protein-coupled receptors in living cells

Nature biotechnology, 2003-07, Vol.21 (7), p.807-812

2003

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β-Arrestin biosensors reveal a rapid, receptor-dependent activation/deactivation cycle

Nature (London), 2016-03, Vol.531 (7596), p.661-664

2016

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GS Activation Is Time-limiting in Initiating Receptor-mediated Signaling

The Journal of biological chemistry, 2006-11, Vol.281 (44), p.33345-33351

2006

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SUMO-1 Controls the Protein Stability and the Biological Function of Phosducin

The Journal of biological chemistry, 2006-03, Vol.281 (13), p.8357-8364

2006

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Visualization of β-adrenergic receptor dynamics and differential localization in cardiomyocytes

Proceedings of the National Academy of Sciences - PNAS, 2021-06, Vol.118 (23), p.1-10

2021

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Raf Kinase Inhibitor Protein (RKIP) Dimer Formation Controls Its Target Switch from Raf1 to G Protein-coupled Receptor Kinase (GRK) 2

The Journal of biological chemistry, 2012-07, Vol.287 (28), p.23407-23417

2012

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Persistent cAMP signaling by internalized TSH receptors occurs in thyroid but not in HEK293 cells

The FASEB journal, 2012-05, Vol.26 (5), p.2043-2048

2012

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Nonequilibrium activation of a G-protein-coupled receptor

Molecular pharmacology, 2012-06, Vol.81 (6), p.770-777

2012

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Molecular basis of inverse agonism in a G protein-coupled receptor

Nature chemical biology, 2005-06, Vol.1 (1), p.25-28

2005

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Site-Specific, Orthogonal Labeling of Proteins in Intact Cells with Two Small Biarsenical Fluorophores

Bioconjugate chemistry, 2010-05, Vol.21 (5), p.853-859

2010

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Interplay of Ca2+ and cAMP Signaling in the Insulin-secreting MIN6 β-Cell Line[boxs]

The Journal of biological chemistry, 2005-09, Vol.280 (35), p.31294-31302

2005

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Distinct pools of cAMP centre on different isoforms of adenylyl cyclase in pituitary-derived GH₃B₆ cells

Journal of cell science, 2010-01, Vol.123 (1), p.95-106

2010

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Real-time monitoring of phosphodiesterase inhibition in intact cells

Cellular signalling, 2008-08, Vol.20 (8), p.1423-1431

2008

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Direct inhibition of cardiac hyperpolarization-activated cyclic nucleotide-gated pacemaker channels by clonidine

Circulation (New York, N.Y.), 2007-02, Vol.115 (7), p.872-880

2007

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Regulation of Phosducin-like Protein by Casein Kinase 2 and N-terminal Splicing

The Journal of biological chemistry, 2003-02, Vol.278 (7), p.4474-4481

2003

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Alterations of Phospholamban Function Can Exhibit Cardiotoxic Effects Independent of Excessive Sarcoplasmic Reticulum Ca2+-ATPase Inhibition

Circulation (New York, N.Y.), 2009-01, Vol.119 (3), p.436-444

2009

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Internalization Determinants of the Parathyroid Hormone Receptor Differentially Regulate β-Arrestin/Receptor Association

The Journal of biological chemistry, 2002-03, Vol.277 (10), p.8121-8129

2002

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Persistent cAMP-signals triggered by internalized G-protein-coupled receptors

Experimental and mathematical analysis of cAMP nanodomains

Sweet taste receptor expressed in pancreatic beta-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion

Analysis of receptor oligomerization by FRAP microscopy

Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2

Novel Single Chain cAMP Sensors for Receptor-induced Signal Propagation

Role of membrane microdomains in compartmentation of cAMP signaling

Dynamics of receptor/G protein coupling in living cells

Measurement of the millisecond activation switch of G protein-coupled receptors in living cells

β-Arrestin biosensors reveal a rapid, receptor-dependent activation/deactivation cycle

GS Activation Is Time-limiting in Initiating Receptor-mediated Signaling

SUMO-1 Controls the Protein Stability and the Biological Function of Phosducin

Visualization of β-adrenergic receptor dynamics and differential localization in cardiomyocytes

Raf Kinase Inhibitor Protein (RKIP) Dimer Formation Controls Its Target Switch from Raf1 to G Protein-coupled Receptor Kinase (GRK) 2

Persistent cAMP signaling by internalized TSH receptors occurs in thyroid but not in HEK293 cells

Nonequilibrium activation of a G-protein-coupled receptor

Molecular basis of inverse agonism in a G protein-coupled receptor

Site-Specific, Orthogonal Labeling of Proteins in Intact Cells with Two Small Biarsenical Fluorophores

Interplay of Ca2+ and cAMP Signaling in the Insulin-secreting MIN6 β-Cell Line[boxs]

Distinct pools of cAMP centre on different isoforms of adenylyl cyclase in pituitary-derived GH₃B₆ cells

Real-time monitoring of phosphodiesterase inhibition in intact cells

Direct inhibition of cardiac hyperpolarization-activated cyclic nucleotide-gated pacemaker channels by clonidine

Regulation of Phosducin-like Protein by Casein Kinase 2 and N-terminal Splicing

Alterations of Phospholamban Function Can Exhibit Cardiotoxic Effects Independent of Excessive Sarcoplasmic Reticulum Ca2+-ATPase Inhibition

Internalization Determinants of the Parathyroid Hormone Receptor Differentially Regulate β-Arrestin/Receptor Association

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