UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 31

Sortiert nach

Photoactivated γ-secretase inhibitors directed to the active site covalently label presenilin 1

Nature (London), 2000-06, Vol.405 (6787), p.689-694

2000

Link zum Volltext

Verfügbarkeit prüfen

C‐terminal PAL motif of presenilin and presenilin homologues required for normal active site conformation

Journal of neurochemistry, 2006-01, Vol.96 (1), p.218-227

2006

Link zum Volltext

Verfügbarkeit prüfen

Quantification of Alzheimer pathology in ageing and dementia: age-related accumulation of amyloid-β(42) peptide in vascular dementia

Neuropathology and applied neurobiology, 2006-04, Vol.32 (2), p.103-118

2006

Link zum Volltext

Verfügbarkeit prüfen

Inhibition of PC12 Cell Redox Activity is a Specific, Early Indicator of the Mechanism of β-Amyloid-Mediated Cell Death

Proceedings of the National Academy of Sciences - PNAS, 1994-02, Vol.91 (4), p.1470-1474

1994

Link zum Volltext

Verfügbarkeit prüfen

4-Substituted cyclohexyl sulfones as potent, orally active γ-secretase inhibitors

Bioorganic & medicinal chemistry letters, 2006-01, Vol.16 (2), p.280-284

2006

Link zum Volltext

Verfügbarkeit prüfen

The Intracellular Component of Cellular 3‐(4,5‐Dimethylthiazol‐2‐yl)‐2,5‐Diphenyltetrazolium Bromide (MTT) Reduction Is Specifically Inhibited by β‐Amyloid Peptides

Journal of neurochemistry, 1995-07, Vol.65 (1), p.218-227

1995

Link zum Volltext

Verfügbarkeit prüfen

Two domains within the first putative transmembrane domain of presenilin 1 differentially influence presenilinase and γ‐secretase activity

Journal of neurochemistry, 2005-09, Vol.94 (5), p.1315-1328

2005

Link zum Volltext

Verfügbarkeit prüfen

Quantitation of amyloid-β peptides in biological milieu using a novel homogeneous time-resolved fluorescence (HTRF) assay

Journal of neuroscience methods, 2000-10, Vol.102 (1), p.61-68

2000

Link zum Volltext

Verfügbarkeit prüfen

A novel series of potent γ-secretase inhibitors based on a benzobicyclo[4.2.1]nonane core

Bioorganic & medicinal chemistry letters, 2005-01, Vol.15 (2), p.373-378

2005

Link zum Volltext

Verfügbarkeit prüfen

Conserved residues within the putative active site of γ‐secretase differentially influence enzyme activity and inhibitor binding

Journal of neurochemistry, 2004-09, Vol.90 (6), p.1312-1320

2004

Link zum Volltext

Verfügbarkeit prüfen

Synthesis and γ-secretase activity of APP substrate-based hydroxyethylene dipeptide isosteres

Bioorganic & medicinal chemistry letters, 2003-01, Vol.13 (1), p.37-41

2003

Link zum Volltext

Verfügbarkeit prüfen

Novel aspects of accumulation dynamics and Aβ composition in transgenic models of AD

Neurobiology of aging, 2004-10, Vol.25 (9), p.1175-1185

2004

Link zum Volltext

Verfügbarkeit prüfen

γ-Secretase: characterization and implication for Alzheimer disease therapy

Neurobiology of aging, 2002-11, Vol.23 (6), p.1023-1030

2002

Link zum Volltext

Verfügbarkeit prüfen

Distinct cellular expression of beta I- and beta II-subspecies of protein kinase C in rat cerebellum

The Journal of neuroscience, 1988-10, Vol.8 (10), p.3850-3856

1988

Link zum Volltext

Verfügbarkeit prüfen

Cerebrospinal fluid levels of β-amyloid(42) in patients with Alzheimerʼs disease are related to the exon 2 polymorphism of the cathepsin D gene

Neuroreport, 2002-07, Vol.13 (10), p.1291-1294

2002

Link zum Volltext

Verfügbarkeit prüfen

Sulfated glycosaminoglycans and dyes attenuate the neurotoxic effects of β-amyloid in rat PC12 cells

Neuroscience letters, 1995-01, Vol.184 (2), p.113-116

1995

Link zum Volltext

Verfügbarkeit prüfen

Sulfonated dyes attenuate the toxic effects of β-amyloid in a structure-specific fashion

Neuroscience letters, 1995-09, Vol.197 (3), p.211-214

1995

Link zum Volltext

Verfügbarkeit prüfen

Selective activation of the γ‐subspecies of protein kinase C from bovine cerebellum by arachidonic acid and its lipoxygenase metabolites

FEBS letters, 1989-01, Vol.243 (2), p.177-182

1989

Link zum Volltext

Verfügbarkeit prüfen

Cellular MTT reduction distinguishes the mechanism of action of β-amyloid from that of tachykinin receptor peptides

Neuropeptides (Edinburgh), 1996-04, Vol.30 (2), p.125-132

Shearman, M.S

1996

Link zum Volltext

Verfügbarkeit prüfen

Synaptosomal Protein Kinase C Subspecies: B. Down‐Regulation Promoted by Phorbol Ester and Its Effect on Evoked Norepinephrine Release

Journal of neurochemistry, 1991-04, Vol.56 (4), p.1263-1269

1991

Link zum Volltext

Verfügbarkeit prüfen

Mouse cortical neurones lacking APP show normal neurite outgrowth and survival responses in vitro

Neuroreport, 1998-09, Vol.9 (13), p.3053-3058

1998

Link zum Volltext

Verfügbarkeit prüfen

Protein kinase C subspecies in adult rat hippocampal synaptosomes Activation by diacylglycerol and arachidonic acid

FEBS letters, 1991-02, Vol.279 (2), p.261-264

1991

Link zum Volltext

Verfügbarkeit prüfen

Sulphated compounds attenuate β-amyloid toxicity by inhibiting its association with cells

Neuroreport, 1995-12, Vol.7 (1), p.49-53

1995

Link zum Volltext

Verfügbarkeit prüfen

The common structure and activities of four subspecies of rat brain protein kinase C family

FEBS letters, 1987-11, Vol.223 (2), p.212-216

1987

Link zum Volltext

Verfügbarkeit prüfen

Protein kinase C activation enhances the delayed rectifier potassium current in guinea-pig heart cells

Journal of molecular and cellular cardiology, 1990-06, Vol.22 (6), p.725-734

1990

Link zum Volltext

Verfügbarkeit prüfen

1 – 25 von 31

Suche als RSS-Feed

Aktive Filter

ThemaBiological And Medical Sciences

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(30)
Mit Volltextzugriff
(28)

Publikationsform

Artikel
(31)

Sprache

Englisch
(31)
Japanisch
(3)

Erscheinungsjahr

n.n

Thema

Science & Technology
(27)
Life Sciences & Biomedicine
(25)
Animals
(21)
Medical Sciences
(18)
Fundamental And Applied Biological Sciences. Psychology
(15)
Humans
(15)
Neurosciences
(15)
Neurosciences & Neurology
(15)
Neurology
(13)
Alzheimer's Disease
(12)
Rats
(11)
Biochemistry & Molecular Biology
(10)
Amyloid Precursor Protein Secretases
(8)
Structure-Activity Relationship
(8)
Molecular Sequence Data
(7)
Protein Kinase C
(7)
Protein Kinase C - Metabolism
(7)
Β-Amyloid
(7)
Amino Acid Sequence
(6)

14 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Photoactivated γ-secretase inhibitors directed to the active site covalently label presenilin 1

C‐terminal PAL motif of presenilin and presenilin homologues required for normal active site conformation

Quantification of Alzheimer pathology in ageing and dementia: age-related accumulation of amyloid-β(42) peptide in vascular dementia

Inhibition of PC12 Cell Redox Activity is a Specific, Early Indicator of the Mechanism of β-Amyloid-Mediated Cell Death

4-Substituted cyclohexyl sulfones as potent, orally active γ-secretase inhibitors

The Intracellular Component of Cellular 3‐(4,5‐Dimethylthiazol‐2‐yl)‐2,5‐Diphenyltetrazolium Bromide (MTT) Reduction Is Specifically Inhibited by β‐Amyloid Peptides

Two domains within the first putative transmembrane domain of presenilin 1 differentially influence presenilinase and γ‐secretase activity

Quantitation of amyloid-β peptides in biological milieu using a novel homogeneous time-resolved fluorescence (HTRF) assay

A novel series of potent γ-secretase inhibitors based on a benzobicyclo[4.2.1]nonane core

Conserved residues within the putative active site of γ‐secretase differentially influence enzyme activity and inhibitor binding

Synthesis and γ-secretase activity of APP substrate-based hydroxyethylene dipeptide isosteres

Novel aspects of accumulation dynamics and Aβ composition in transgenic models of AD

γ-Secretase: characterization and implication for Alzheimer disease therapy

Distinct cellular expression of beta I- and beta II-subspecies of protein kinase C in rat cerebellum

Cerebrospinal fluid levels of β-amyloid(42) in patients with Alzheimerʼs disease are related to the exon 2 polymorphism of the cathepsin D gene

Sulfated glycosaminoglycans and dyes attenuate the neurotoxic effects of β-amyloid in rat PC12 cells

Sulfonated dyes attenuate the toxic effects of β-amyloid in a structure-specific fashion

Selective activation of the γ‐subspecies of protein kinase C from bovine cerebellum by arachidonic acid and its lipoxygenase metabolites

Cellular MTT reduction distinguishes the mechanism of action of β-amyloid from that of tachykinin receptor peptides

Synaptosomal Protein Kinase C Subspecies: B. Down‐Regulation Promoted by Phorbol Ester and Its Effect on Evoked Norepinephrine Release

Mouse cortical neurones lacking APP show normal neurite outgrowth and survival responses in vitro

Protein kinase C subspecies in adult rat hippocampal synaptosomes Activation by diacylglycerol and arachidonic acid

Sulphated compounds attenuate β-amyloid toxicity by inhibiting its association with cells

The common structure and activities of four subspecies of rat brain protein kinase C family

Protein kinase C activation enhances the delayed rectifier potassium current in guinea-pig heart cells

Aktive Filter

Suchergebnisse filtern