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Observing cellulose biosynthesis and membrane translocation in crystallo

Nature (London), 2016-03, Vol.531 (7594), p.329-334

2016

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Order and Disorder: Differential Structural Impacts of Myricetin and Ethyl Caffeate on Human Amylase, an Antidiabetic Target

Journal of medicinal chemistry, 2012-11, Vol.55 (22), p.10177-10186

2012

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The amylase inhibitor montbretin A reveals a new glycosidase inhibition motif

Nature chemical biology, 2015-09, Vol.11 (9), p.691

2015

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Rapid Discovery of Potent and Selective Glycosidase-Inhibiting De Novo Peptides

Cell chemical biology, 2017-03, Vol.24 (3), p.381-390

2017

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Structure and Mechanism of Chitin Deacetylase from the Fungal Pathogen Colletotrichum lindemuthianum

Biochemistry (Easton), 2006-08, Vol.45 (31), p.9416-9426

2006

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X-ray crystallographic structure of a bacterial polysialyltransferase provides insight into the biosynthesis of capsular polysialic acid

Scientific reports, 2017-07, Vol.7 (1), p.5842-13, Article 5842

2017

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Mechanistic Insights into the Chaperoning of Human Lysosomal-Galactosidase Activity: Highly Functionalized Aminocyclopentanes and C -5a-Substituted Derivatives of 4- epi -Isofagomine

Molecules (Basel, Switzerland), 2020-09, Vol.25 (17), p.4025

2020

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Crystal structure of the retaining galactosyltransferase LgtC from Neisseria meningitidis in complex with donor and acceptor sugar analogs

Nature structural & molecular biology, 2001-02, Vol.8 (2), p.166-175

2001

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Directed Evolution of a Glycosynthase from Agrobacterium sp. Increases Its Catalytic Activity Dramatically and Expands Its Substrate Repertoire

The Journal of biological chemistry, 2004-10, Vol.279 (41), p.42787-42793

2004

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A Structural View of the Action of Escherichia coli (lacZ) β-Galactosidase

Biochemistry (Easton), 2001-12, Vol.40 (49), p.14781-14794

2001

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Dissecting the Electrostatic Interactions and pH-Dependent Activity of a Family 11 Glycosidase

Biochemistry (Easton), 2001-08, Vol.40 (34), p.10115-10139

2001

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Mechanisms of enzymatic glycoside hydrolysis

Current opinion in structural biology, 1994, Vol.4 (6), p.885-892

1994

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Mechanistic and Structural Analysis of a Family 31 α-Glycosidase and Its Glycosyl-enzyme Intermediate

The Journal of biological chemistry, 2005-01, Vol.280 (3), p.2105-2115

2005

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Intermediate trapping on a mutant retaining alpha-galactosyltransferase identifies an unexpected aspartate residue

The Journal of biological chemistry, 2004-07, Vol.279 (27), p.28339-28344

2004

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Subsite Mapping of the Human Pancreatic α-Amylase Active Site through Structural, Kinetic, and Mutagenesis Techniques

Biochemistry (Easton), 2000-04, Vol.39 (16), p.4778-4791

2000

Volltextzugriff (PDF)

Mechanism of GlvA from Bacillus subtilis: A Detailed Kinetic Analysis of a 6-Phospho-α-glucosidase from Glycoside Hydrolase Family 4

Biochemistry (Easton), 2007-08, Vol.46 (34), p.9840-9852

2007

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Branched montbretin A mimics allow derivatisation and potent amylase inhibition

Organic & biomolecular chemistry, 2023-10, Vol.21 (39), p.7977-7983

2023

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Evaluation of the Significance of Starch Surface Binding Sites on Human Pancreatic α‑Amylase

Biochemistry (Easton), 2016-11, Vol.55 (43), p.6000-6009

2016

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Insights into Heptosyltransferase I Catalysis and Inhibition through the Structure of Its Ternary Complex

Structure (London), 2018-10, Vol.26 (10), p.1399-1407.e5

2018

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Mechanism of Agrobacterium .beta.-glucosidase: kinetic analysis of the role of noncovalent enzyme/substrate interactions

Biochemistry (Easton), 1995-12, Vol.34 (49), p.16194-16202

1995

Volltextzugriff (PDF)

Structural basis for Lewis antigen synthesis by the α1,3-fucosyltransferase FUT9

Nature chemical biology, 2023-08, Vol.19 (8), p.1022

2023

Volltextzugriff (PDF)

Paenibacillus sp. TS12 glucosylceramidase: kinetic studies of a novel sub-family of family 3 glycosidases and identification of the catalytic residues

Biochemical journal, 2004-02, Vol.378 (Pt 1), p.141-149

2004

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Active-site peptide "fingerprinting" of glycosidases in complex mixtures by mass spectrometry. Discovery of a novel retaining beta-1,4-glycanase in Cellulomonas fimi

The Journal of biological chemistry, 2005-10, Vol.280 (42), p.35126-35135

2005

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Direct Observation of the Protonation State of an Imino Sugar Glycosidase Inhibitor upon Binding

Journal of the American Chemical Society, 2003-06, Vol.125 (25), p.7496-7497

2003

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Approaches to labeling and identification of active site residues in glycosidases

Protein science, 1995-03, Vol.4 (3), p.361-372

1995

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Observing cellulose biosynthesis and membrane translocation in crystallo

Order and Disorder: Differential Structural Impacts of Myricetin and Ethyl Caffeate on Human Amylase, an Antidiabetic Target

The amylase inhibitor montbretin A reveals a new glycosidase inhibition motif

Rapid Discovery of Potent and Selective Glycosidase-Inhibiting De Novo Peptides

Structure and Mechanism of Chitin Deacetylase from the Fungal Pathogen Colletotrichum lindemuthianum

X-ray crystallographic structure of a bacterial polysialyltransferase provides insight into the biosynthesis of capsular polysialic acid

Mechanistic Insights into the Chaperoning of Human Lysosomal-Galactosidase Activity: Highly Functionalized Aminocyclopentanes and C -5a-Substituted Derivatives of 4- epi -Isofagomine

Crystal structure of the retaining galactosyltransferase LgtC from Neisseria meningitidis in complex with donor and acceptor sugar analogs

Directed Evolution of a Glycosynthase from Agrobacterium sp. Increases Its Catalytic Activity Dramatically and Expands Its Substrate Repertoire

A Structural View of the Action of Escherichia coli (lacZ) β-Galactosidase

Dissecting the Electrostatic Interactions and pH-Dependent Activity of a Family 11 Glycosidase

Mechanisms of enzymatic glycoside hydrolysis

Mechanistic and Structural Analysis of a Family 31 α-Glycosidase and Its Glycosyl-enzyme Intermediate

Intermediate trapping on a mutant retaining alpha-galactosyltransferase identifies an unexpected aspartate residue

Subsite Mapping of the Human Pancreatic α-Amylase Active Site through Structural, Kinetic, and Mutagenesis Techniques

Mechanism of GlvA from Bacillus subtilis: A Detailed Kinetic Analysis of a 6-Phospho-α-glucosidase from Glycoside Hydrolase Family 4

Branched montbretin A mimics allow derivatisation and potent amylase inhibition

Evaluation of the Significance of Starch Surface Binding Sites on Human Pancreatic α‑Amylase

Insights into Heptosyltransferase I Catalysis and Inhibition through the Structure of Its Ternary Complex

Mechanism of Agrobacterium .beta.-glucosidase: kinetic analysis of the role of noncovalent enzyme/substrate interactions

Structural basis for Lewis antigen synthesis by the α1,3-fucosyltransferase FUT9

Paenibacillus sp. TS12 glucosylceramidase: kinetic studies of a novel sub-family of family 3 glycosidases and identification of the catalytic residues

Active-site peptide "fingerprinting" of glycosidases in complex mixtures by mass spectrometry. Discovery of a novel retaining beta-1,4-glycanase in Cellulomonas fimi

Direct Observation of the Protonation State of an Imino Sugar Glycosidase Inhibitor upon Binding

Approaches to labeling and identification of active site residues in glycosidases

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