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Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection

Immunity (Cambridge, Mass.), 2023-09, Vol.56 (9), p.2036-2053.e12

2023

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Arginase: an old enzyme with new tricks

Trends in pharmacological sciences (Regular ed.), 2015-06, Vol.36 (6), p.395-405

2015

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Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma

Nature communications, 2019-07, Vol.10 (1), p.3000-16, Article 3000

2019

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Dietary flavonoids fisetin, luteolin and their derived compounds inhibit arginase, a central enzyme in Leishmania (Leishmania) amazonensis infection

Food chemistry, 2013-12, Vol.141 (3), p.2253-2262

2013

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Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation

Nature immunology, 2016-06, Vol.17 (6), p.656

2016

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Amino acid metabolism as drug target in autoimmune diseases

Autoimmunity reviews, 2019-04, Vol.18 (4), p.334-348

2019

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Autophagy maintains tumour growth through circulating arginine

Nature (London), 2018-11, Vol.563 (7732), p.569-573

2018

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ARG2 impairs endothelial autophagy through regulation of MTOR and PRKAA/AMPK signaling in advanced atherosclerosis

Autophagy, 2014-12, Vol.10 (12), p.2223-2238

2014

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Targeting the arginine metabolic brake enhances immunotherapy for leukaemia

International journal of cancer, 2019-10, Vol.145 (8), p.2201-2208

2019

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Obesity-induced vascular dysfunction and arterial stiffening requires endothelial cell arginase 1

Cardiovascular research, 2017-11, Vol.113 (13), p.1664-1676

2017

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The role of arginase in aging: A systematic review

Experimental gerontology, 2019-02, Vol.116, p.54-73

2019

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Modulation of M1/M2 polarization by capsaicin contributes to the survival of dopaminergic neurons in the lipopolysaccharide-lesioned substantia nigra in vivo

Experimental and Molecular Medicine, 2018, 50(0), , pp.1-14

2018

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Arginase 1 and L‐arginine coordinate fetal lung development and the initiation of labor in mice

EMBO reports, 2023-08, Vol.24 (8), p.e56352-n/a

2023

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Lipid nanoparticle-targeted mRNA therapy as a treatment for the inherited metabolic liver disorder arginase deficiency

Proceedings of the National Academy of Sciences - PNAS, 2019-10, Vol.116 (42), p.21150-21159

2019

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Posttranslationally Acting Arginases Provide a Ribosomal Route to Non‐proteinogenic Ornithine Residues in Diverse Peptide Sequences

Angewandte Chemie International Edition, 2020-11, Vol.59 (48), p.21442-21447

International ed. in English, 2020

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Arginase 2 is a mediator of ischemia–reperfusion injury in the kidney through regulation of nitrosative stress

Kidney international, 2020-09, Vol.98 (3), p.673-685

2020

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STAT3 regulates arginase-I in myeloid-derived suppressor cells from cancer patients

The Journal of clinical investigation, 2013-04, Vol.123 (4), p.1580-1589

2013

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Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis

Immunity (Cambridge, Mass.), 2020-07, Vol.53 (1), p.204-216.e10

2020

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In situ and real-time imaging of superoxide anion and peroxynitrite elucidating arginase 1 nitration aggravating hepatic ischemia-reperfusion injury

Biomaterials, 2019-12, Vol.225, p.119499, Article 119499

2019

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Urea cycle disorders-update

Journal of human genetics, 2019-09, Vol.64 (9), p.833-847

2019

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Py-CoMFA, docking, and molecular dynamics simulations of Leishmania (L.) amazonensis arginase inhibitors

Scientific reports, 2024-05, Vol.14 (1), p.11575-11575, Article 11575

2024

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Arginase: A Multifaceted Enzyme Important in Health and Disease

Physiological reviews, 2018-04, Vol.98 (2), p.641-665

2018

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Arginase Inhibitors: A Rational Approach Over One Century

Medicinal research reviews, 2017-05, Vol.37 (3), p.475-513

2017

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Arginase inhibitor reduces fungal dissemination in murine pulmonary cryptococcosis by promoting anti-cryptococcal immunity

International immunopharmacology, 2024-05, Vol.132, p.111995-111995, Article 111995

2024

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Arginine deprivation in cancer therapy

Current opinion in clinical nutrition and metabolic care, 2015-01, Vol.18 (1), p.78-82

2015

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Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection

Arginase: an old enzyme with new tricks

Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma

Dietary flavonoids fisetin, luteolin and their derived compounds inhibit arginase, a central enzyme in Leishmania (Leishmania) amazonensis infection

Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation

Amino acid metabolism as drug target in autoimmune diseases

Autophagy maintains tumour growth through circulating arginine

ARG2 impairs endothelial autophagy through regulation of MTOR and PRKAA/AMPK signaling in advanced atherosclerosis

Targeting the arginine metabolic brake enhances immunotherapy for leukaemia

Obesity-induced vascular dysfunction and arterial stiffening requires endothelial cell arginase 1

The role of arginase in aging: A systematic review

Modulation of M1/M2 polarization by capsaicin contributes to the survival of dopaminergic neurons in the lipopolysaccharide-lesioned substantia nigra in vivo

Arginase 1 and L‐arginine coordinate fetal lung development and the initiation of labor in mice

Lipid nanoparticle-targeted mRNA therapy as a treatment for the inherited metabolic liver disorder arginase deficiency

Posttranslationally Acting Arginases Provide a Ribosomal Route to Non‐proteinogenic Ornithine Residues in Diverse Peptide Sequences

Arginase 2 is a mediator of ischemia–reperfusion injury in the kidney through regulation of nitrosative stress

STAT3 regulates arginase-I in myeloid-derived suppressor cells from cancer patients

Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis

In situ and real-time imaging of superoxide anion and peroxynitrite elucidating arginase 1 nitration aggravating hepatic ischemia-reperfusion injury

Urea cycle disorders-update

Py-CoMFA, docking, and molecular dynamics simulations of Leishmania (L.) amazonensis arginase inhibitors

Arginase: A Multifaceted Enzyme Important in Health and Disease

Arginase Inhibitors: A Rational Approach Over One Century

Arginase inhibitor reduces fungal dissemination in murine pulmonary cryptococcosis by promoting anti-cryptococcal immunity

Arginine deprivation in cancer therapy

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