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Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice

Nature communications, 2020-01, Vol.11 (1), p.394-15, Article 394

2020

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No unexpected CRISPR-Cas9 off-target activity revealed by trio sequencing of gene-edited mice

PLoS genetics, 2018-07, Vol.14 (7), p.e1007503

2018

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Cross-species genomic landscape comparison of human mucosal melanoma with canine oral and equine melanoma

Nature communications, 2019-01, Vol.10 (1), p.353-14, Article 353

2019

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WGE: a CRISPR database for genome engineering

Bioinformatics, 2015-09, Vol.31 (18), p.3078-3080

2015

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Off-target mutations are rare in Cas9-modified mice

Nature methods, 2015-06, Vol.12 (6), p.479

2015

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Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia

Nature communications, 2021-04, Vol.12 (1), p.2482-20, Article 2482

2021

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A conditional knockout resource for the genome―wide study of mouse gene function

Nature (London), 2011-06, Vol.474 (7351), p.337-342

2011

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The mutational signature profile of known and suspected human carcinogens in mice

Nature genetics, 2020-11, Vol.52 (11), p.1189

2020

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Collateral damage and CRISPR genome editing

PLoS genetics, 2019-03, Vol.15 (3), p.e1007994

2019

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Genome-wide Generation and Systematic Phenotyping of Knockout Mice Reveals New Roles for Many Genes

Cell, 2013-07, Vol.154 (2), p.452-464

2013

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Combinatorial CRISPR screen identifies fitness effects of gene paralogues

Nature communications, 2021-02, Vol.12 (1), p.1302-1302, Article 1302

2021

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XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data

BMC bioinformatics, 2018-10, Vol.19 (1), p.366-15, Article 366

2018

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Mitochondrial oxidative stress during cardiac lipid overload causes intracellular calcium leak and arrhythmia

Heart rhythm, 2016-08, Vol.13 (8), p.1699-1706

2016

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mammalian gene function resource: the international knockout mouse consortium

Mammalian genome, 2012-10, Vol.23 (9-10), p.580-586

2012

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KCNE1 alters the voltage sensor movements necessary to open the KCNQ1 channel gate

Proceedings of the National Academy of Sciences - PNAS, 2010-12, Vol.107 (52), p.22710-22715

2010

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Applying the ARRIVE Guidelines to an In Vivo Database

PLoS biology, 2015-05, Vol.13 (5), p.e1002151-e1002151

2015

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Enhancing the genome editing toolbox: genome wide CRISPR arrayed libraries

Scientific reports, 2017-05, Vol.7 (1), p.2244-9, Article 2244

2017

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CRISPR activation screen in mice identifies novel membrane proteins enhancing pulmonary metastatic colonisation

Communications biology, 2021-03, Vol.4 (1), p.395-395, Article 395

2021

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An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers

Nucleic acids research, 2017-12, Vol.45 (21), p.e174

2017

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Neuropilin-1 deficiency in vascular smooth muscle cells is associated with hereditary hemorrhagic telangiectasia arteriovenous malformations

JCI insight, 2022-05, Vol.7 (9)

2022

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Accessing data from the International Mouse Phenotyping Consortium: state of the art and future plans

Mammalian genome, 2012-10, Vol.23 (9-10), p.641-652

2012

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Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects

Nature methods, 2014-04, Vol.11 (4), p.399

2014

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A Genome-Wide Association Study for Regulators of Micronucleus Formation in Mice

G3 : genes - genomes - genetics, 2016-08, Vol.6 (8), p.2343-2354

2016

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Best practice for CRISPR design using current tools and resources

Methods (San Diego, Calif.), 2019-07, Vol.164-165, p.3-17

2019

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Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice

No unexpected CRISPR-Cas9 off-target activity revealed by trio sequencing of gene-edited mice

Cross-species genomic landscape comparison of human mucosal melanoma with canine oral and equine melanoma

WGE: a CRISPR database for genome engineering

Off-target mutations are rare in Cas9-modified mice

Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia

A conditional knockout resource for the genome―wide study of mouse gene function

The mutational signature profile of known and suspected human carcinogens in mice

Collateral damage and CRISPR genome editing

Genome-wide Generation and Systematic Phenotyping of Knockout Mice Reveals New Roles for Many Genes

Combinatorial CRISPR screen identifies fitness effects of gene paralogues

XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data

Mitochondrial oxidative stress during cardiac lipid overload causes intracellular calcium leak and arrhythmia

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

mammalian gene function resource: the international knockout mouse consortium

KCNE1 alters the voltage sensor movements necessary to open the KCNQ1 channel gate

Applying the ARRIVE Guidelines to an In Vivo Database

Enhancing the genome editing toolbox: genome wide CRISPR arrayed libraries

CRISPR activation screen in mice identifies novel membrane proteins enhancing pulmonary metastatic colonisation

An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers

Neuropilin-1 deficiency in vascular smooth muscle cells is associated with hereditary hemorrhagic telangiectasia arteriovenous malformations

Accessing data from the International Mouse Phenotyping Consortium: state of the art and future plans

Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects

A Genome-Wide Association Study for Regulators of Micronucleus Formation in Mice

Best practice for CRISPR design using current tools and resources

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