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Selective induction of cancer cell death by VDAC1‐based peptides and their potential use in cancer therapy

Molecular oncology, 2018-06, Vol.12 (7), p.1077-1103

2018

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VDAC1 in the diseased myocardium and the effect of VDAC1-interacting compound on atrial fibrosis induced by hyperaldosteronism

Scientific reports, 2020-12, Vol.10 (1), p.22101-22101, Article 22101

2020

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VDAC1 and the TSPO: Expression, Interactions, and Associated Functions in Health and Disease States

International journal of molecular sciences, 2019-07, Vol.20 (13), p.3348

2019

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Voltage-dependent Anion Channel 1-based Peptides Interact with Bcl-2 to Prevent Antiapoptotic Activity

The Journal of biological chemistry, 2010-02, Vol.285 (9), p.6053-6062

2010

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Oligomerization of the Mitochondrial Protein Voltage-Dependent Anion Channel Is Coupled to the Induction of Apoptosis

Molecular and Cellular Biology, 2010-12, Vol.30 (24), p.5698-5709

2010

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Targeting Liver Cancer and Associated Pathologies in Mice with a Mitochondrial VDAC1-Based Peptide

Neoplasia (New York, N.Y.), 2018-06, Vol.20 (6), p.594-609

2018

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VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease

Science (American Association for the Advancement of Science), 2019-12, Vol.366 (6472), p.1531-1536

2019

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NCLX is an essential component of mitochondrial Na⁺/Ca²⁺ exchange

Proceedings of the National Academy of Sciences - PNAS, 2010-01, Vol.107 (1), p.436-441

2010

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Misfolded Mutant SOD1 Directly Inhibits VDAC1 Conductance in a Mouse Model of Inherited ALS

Neuron (Cambridge, Mass.), 2010-08, Vol.67 (4), p.575-587

2010

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Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction

The Journal of biological chemistry, 2016-11, Vol.291 (48), p.24986-25003

2016

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VDAC1-Based Peptides as Potential Modulators of VDAC1 Interactions with Its Partners and as a Therapeutic for Cancer, NASH, and Diabetes

Biomolecules (Basel, Switzerland), 2024-09, Vol.14 (9), p.1139

2024

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Voltage-dependent Anion Channel 1-based Peptides Interact with Hexokinase to Prevent Its Anti-apoptotic Activity

The Journal of biological chemistry, 2009-02, Vol.284 (6), p.3946-3955

2009

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Uncovering the role of VDAC in the regulation of cell life and death

Journal of bioenergetics and biomembranes, 2008-06, Vol.40 (3), p.183-191

2008

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Apoptosis is regulated by the VDAC1 N-terminal region and by VDAC oligomerization: release of cytochrome c, AIF and Smac/Diablo

Biochimica et biophysica acta, 2010-06, Vol.1797 (6-7), p.1281-1291

2010

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Targeting the overexpressed mitochondrial protein VDAC1 in a mouse model of Alzheimer's disease protects against mitochondrial dysfunction and mitigates brain pathology

Translational neurodegeneration, 2022-12, Vol.11 (1), p.58-30, Article 58

2022

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VDAC1 N-terminus is essential both for apoptosis and the protective effect of anti-apoptotic proteins

Journal of cell science, 2009-06, Vol.122 (11), p.1906-1916

2009

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Empty mesoporous silica particles significantly delay disease progression and extend survival in a mouse model of ALS

Scientific reports, 2020-11, Vol.10 (1), p.20675-20675, Article 20675

2020

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Oligomerization of the Mitochondrial Protein VDAC1: From Structure to Function and Cancer Therapy

Progress in Molecular Biology and Translational Science, 2013, Vol.117, p.303-334

2013

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Silencing the Mitochondrial Gatekeeper VDAC1 as a Potential Treatment for Bladder Cancer

Cells (Basel, Switzerland), 2024-04, Vol.13 (7), p.627

2024

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Calcium binding and translocation by the voltage-dependent anion channel: a possible regulatory mechanism in mitochondrial function

Biochemical journal, 2001-08, Vol.358 (Pt 1), p.147-155

2001

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Downregulation of voltage-dependent anion channel-1 expression by RNA interference prevents cancer cell growth in vivo

Cancer biology & therapy, 2010-06, Vol.9 (12), p.1046-1052

2010

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VDAC1 cysteine residues: topology and function in channel activity and apoptosis

Biochemical journal, 2010-05, Vol.427 (3), p.445-454

2010

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Oligomeric states of the voltage-dependent anion channel and cytochrome c release from mitochondria

Biochemical journal, 2005-02, Vol.386 (Pt 1), p.73-83

2005

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The voltage-dependent anion channel: characterization, modulation, and role in mitochondrial function in cell life and death

Cell biochemistry and biophysics, 2003-01, Vol.39 (3), p.279-292

2003

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Fluoxetine (Prozac) interaction with the mitochondrial voltage-dependent anion channel and protection against apoptotic cell death

FEBS letters, 2005-09, Vol.579 (22), p.5105-5110

2005

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Selective induction of cancer cell death by VDAC1‐based peptides and their potential use in cancer therapy

VDAC1 in the diseased myocardium and the effect of VDAC1-interacting compound on atrial fibrosis induced by hyperaldosteronism

VDAC1 and the TSPO: Expression, Interactions, and Associated Functions in Health and Disease States

Voltage-dependent Anion Channel 1-based Peptides Interact with Bcl-2 to Prevent Antiapoptotic Activity

Oligomerization of the Mitochondrial Protein Voltage-Dependent Anion Channel Is Coupled to the Induction of Apoptosis

Targeting Liver Cancer and Associated Pathologies in Mice with a Mitochondrial VDAC1-Based Peptide

VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease

NCLX is an essential component of mitochondrial Na⁺/Ca²⁺ exchange

Misfolded Mutant SOD1 Directly Inhibits VDAC1 Conductance in a Mouse Model of Inherited ALS

Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction

VDAC1-Based Peptides as Potential Modulators of VDAC1 Interactions with Its Partners and as a Therapeutic for Cancer, NASH, and Diabetes

Voltage-dependent Anion Channel 1-based Peptides Interact with Hexokinase to Prevent Its Anti-apoptotic Activity

Uncovering the role of VDAC in the regulation of cell life and death

Apoptosis is regulated by the VDAC1 N-terminal region and by VDAC oligomerization: release of cytochrome c, AIF and Smac/Diablo

Targeting the overexpressed mitochondrial protein VDAC1 in a mouse model of Alzheimer's disease protects against mitochondrial dysfunction and mitigates brain pathology

VDAC1 N-terminus is essential both for apoptosis and the protective effect of anti-apoptotic proteins

Empty mesoporous silica particles significantly delay disease progression and extend survival in a mouse model of ALS

Oligomerization of the Mitochondrial Protein VDAC1: From Structure to Function and Cancer Therapy

Silencing the Mitochondrial Gatekeeper VDAC1 as a Potential Treatment for Bladder Cancer

Calcium binding and translocation by the voltage-dependent anion channel: a possible regulatory mechanism in mitochondrial function

Downregulation of voltage-dependent anion channel-1 expression by RNA interference prevents cancer cell growth in vivo

VDAC1 cysteine residues: topology and function in channel activity and apoptosis

Oligomeric states of the voltage-dependent anion channel and cytochrome c release from mitochondria

The voltage-dependent anion channel: characterization, modulation, and role in mitochondrial function in cell life and death

Fluoxetine (Prozac) interaction with the mitochondrial voltage-dependent anion channel and protection against apoptotic cell death

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