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Design and Synthesis of m1-Selective Muscarinic Agonists: (R)-(−)-(Z)-1-Azabicyclo[2.2.1]heptan-3-one, O-(3-(3‘-Methoxyphenyl)-2-propynyl)- oxime Maleate (CI-1017), a Functionally m1-Selective Muscarinic Agonist

Journal of medicinal chemistry, 1998-07, Vol.41 (14), p.2524-2536

1998

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Synthesis and Sar of bulky 1-azabicyclo[2.2.1]-3-one oximes as muscarinic receptor subtype selective agonists

Life sciences (1973), 1993, Vol.52 (5), p.505-511

1993

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FEATHER DAMAGE DUE TO MYCOTIC INFECTIONS IN WILD TURKEYS

Journal of wildlife diseases, 1989-10, Vol.25 (4), p.534-539

1989

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CI-1017, a functionally M1-selective muscarinic agonist: design, synthesis, and preclinical pharmacology

Pharmaceutica acta Helvetiae, 2000-03, Vol.74 (2-3), p.141-148

2000

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The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases

Bioorganic & medicinal chemistry letters, 2006-05, Vol.16 (9), p.2337-2340

2006

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Identification and characterization of m1 selective muscarinic receptor antagonists1

Journal of medicinal chemistry, 1999-02, Vol.42 (3), p.356-363

1999

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The Genome of the Ctenophore Mnemiopsis leidyi and Its Implications for Cell Type Evolution

Science (American Association for the Advancement of Science), 2013-12, Vol.342 (6164), p.1336-1336

2013

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TRPV1 Receptors in the CNS Play a Key Role in Broad-Spectrum Analgesia of TRPV1 Antagonists

The Journal of neuroscience, 2006-09, Vol.26 (37), p.9385-9393

2006

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Rbx1, a Component of the VHL Tumor Suppressor Complex and SCF Ubiquitin Ligase

Science (American Association for the Advancement of Science), 1999-04, Vol.284 (5414), p.657-661

1999

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Genetics of rheumatoid arthritis contributes to biology and drug discovery

Nature (London), 2014-02, Vol.506 (7488), p.376-381

2014

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Notch signalling drives synovial fibroblast identity and arthritis pathology

Nature (London), 2020-06, Vol.582 (7811), p.259-264

2020

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Structural insights into the stereochemistry of the cyclooxygenase reaction

Nature (London), 2000-05, Vol.405 (6782), p.97-101

2000

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Plasma carboxypeptidase B downregulates inflammatory responses in autoimmune arthritis

The Journal of clinical investigation, 2011-09, Vol.121 (9), p.3517-3527

2011

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Blockade of mGluR1 receptor results in analgesia and disruption of motor and cognitive performances: effects of A‐841720, a novel non‐competitive mGluR1 receptor antagonist

British journal of pharmacology, 2006-11, Vol.149 (6), p.761-774

2006

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Rheumatoid arthritis: developing pharmacological therapies

Expert opinion on investigational drugs, 2004-08, Vol.13 (8), p.1007-1018

2004

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Salmonella enterica causes more severe inflammatory disease in C57/BL6 Nramp1G169 mice than Sv129S6 mice

Veterinary pathology, 2013-09, Vol.50 (5), p.867

2013

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A-412997, a selective dopamine D4 agonist, improves cognitive performance in rats

Pharmacology, biochemistry and behavior, 2005-09, Vol.82 (1), p.148-155

2005

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Ex vivo gene transfer using adenovirus-mediated full-length dystrophin delivery to dystrophic muscles

Gene therapy, 1998, Vol.5 (1), p.19-30

1998

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Dopamine D4 receptor signaling in the rat paraventricular hypothalamic nucleus: Evidence of natural coupling involving immediate early gene induction and mitogen activated protein kinase phosphorylation

Neuropharmacology, 2006-04, Vol.50 (5), p.521-531

2006

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Expansion of visual receptive fields in experimental glaucoma

Visual neuroscience, 2006-01, Vol.23 (1), p.137-142

2006

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A curated online resource for SOX10 and pigment cell molecular genetic pathways

Database : the journal of biological databases and curation, 2010-10, Vol.2010, p.baq025-baq025

2010

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A subset of Cowdria ruminantium genes important for immune recognition and protection

Gene, 2001-09, Vol.275 (2), p.287-298

2001

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Cardioselective anti-ischemic ATP-sensitive potassium channel openers

Journal of medicinal chemistry, 1993-11, Vol.36 (24), p.3971-3974

1993

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3H] A-369508 ([2-[4-(2-cyanophenyl)-1-piperazinyl]-N-(3-methylphenyl) acetamide): an agonist radioligand selective for the dopamine D4 receptor

European journal of pharmacology, 2004-08, Vol.497 (2), p.147-154

2004

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Design and Synthesis of m1-Selective Muscarinic Agonists: (R)-(−)-(Z)-1-Azabicyclo[2.2.1]heptan-3-one, O-(3-(3‘-Methoxyphenyl)-2-propynyl)- oxime Maleate (CI-1017), a Functionally m1-Selective Muscarinic Agonist

Synthesis and Sar of bulky 1-azabicyclo[2.2.1]-3-one oximes as muscarinic receptor subtype selective agonists

FEATHER DAMAGE DUE TO MYCOTIC INFECTIONS IN WILD TURKEYS

CI-1017, a functionally M1-selective muscarinic agonist: design, synthesis, and preclinical pharmacology

The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases

Identification and characterization of m1 selective muscarinic receptor antagonists1

The Genome of the Ctenophore Mnemiopsis leidyi and Its Implications for Cell Type Evolution

TRPV1 Receptors in the CNS Play a Key Role in Broad-Spectrum Analgesia of TRPV1 Antagonists

Rbx1, a Component of the VHL Tumor Suppressor Complex and SCF Ubiquitin Ligase

Genetics of rheumatoid arthritis contributes to biology and drug discovery

Notch signalling drives synovial fibroblast identity and arthritis pathology

Structural insights into the stereochemistry of the cyclooxygenase reaction

Plasma carboxypeptidase B downregulates inflammatory responses in autoimmune arthritis

Blockade of mGluR1 receptor results in analgesia and disruption of motor and cognitive performances: effects of A‐841720, a novel non‐competitive mGluR1 receptor antagonist

Rheumatoid arthritis: developing pharmacological therapies

Salmonella enterica causes more severe inflammatory disease in C57/BL6 Nramp1G169 mice than Sv129S6 mice

Sialic acid catabolism by N-acetylneuraminate pyruvate lyase is essential for muscle function

A-412997, a selective dopamine D4 agonist, improves cognitive performance in rats

Ex vivo gene transfer using adenovirus-mediated full-length dystrophin delivery to dystrophic muscles

Dopamine D4 receptor signaling in the rat paraventricular hypothalamic nucleus: Evidence of natural coupling involving immediate early gene induction and mitogen activated protein kinase phosphorylation

Expansion of visual receptive fields in experimental glaucoma

A curated online resource for SOX10 and pigment cell molecular genetic pathways

A subset of Cowdria ruminantium genes important for immune recognition and protection

Cardioselective anti-ischemic ATP-sensitive potassium channel openers

3H] A-369508 ([2-[4-(2-cyanophenyl)-1-piperazinyl]-N-(3-methylphenyl) acetamide): an agonist radioligand selective for the dopamine D4 receptor

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