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LDL-Cholesterol Reduction by ANGPTL3 Inhibition in Mice Is Dependent on Endothelial Lipase

Circulation research, 2020-09, Vol.127 (8), p.1112-1114

2020

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Endothelial lipase mediates efficient lipolysis of triglyceride-rich lipoproteins

PLoS genetics, 2021-09, Vol.17 (9), p.e1009802-e1009802

2021

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Herbivorous turtle ants obtain essential nutrients from a conserved nitrogen-recycling gut microbiome

Nature communications, 2018-03, Vol.9 (1), p.964-14, Article 964

2018

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A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels

Nature medicine, 2017-09, Vol.23 (9), p.1086-1094

2017

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Hepatic protein phosphatase 1 regulatory subunit 3B (Ppp1r3b) promotes hepatic glycogen synthesis and thereby regulates fasting energy homeostasis

The Journal of biological chemistry, 2017-06, Vol.292 (25), p.10444-10454

2017

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Macrophage Sortilin Promotes LDL Uptake, Foam Cell Formation, and Atherosclerosis

Circulation research, 2015-02, Vol.116 (5), p.789-796

2015

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Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism

The Journal of clinical investigation, 2012-08, Vol.122 (8), p.2807-2816

2012

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TRIB1 regulates LDL metabolism through CEBPα-mediated effects on the LDL receptor in hepatocytes

The Journal of clinical investigation, 2021-11, Vol.131 (22), p.1-11

2021

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Indirect and mitigated effects of pulsed resources on the population dynamics of a northern rodent

The Journal of animal ecology, 2013-07, Vol.82 (4), p.814-825

2013

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ILRUN, a Human Plasma Lipid GWAS Locus, Regulates Lipoprotein Metabolism in Mice

Circulation research, 2020-11, Vol.127 (11), p.1347-1361

2020

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Functional Analysis and Transcriptomic Profiling of iPSC-Derived Macrophages and Their Application in Modeling Mendelian Disease

Circulation research, 2015-06, Vol.117 (1), p.17-28

2015

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Reduced sterol regulatory element‐binding protein (SREBP) processing through site‐1 protease (S1P) inhibition alters oligodendrocyte differentiation in vitro

Journal of neurochemistry, 2017-01, Vol.140 (1), p.53-67

2017

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Determining hepatic triglyceride production in mice: comparison of poloxamer 407 with Triton WR-1339

Journal of lipid research, 2005-09, Vol.46 (9), p.2023-2028

2005

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ApoA-I-Directed Therapies for the Management of Atherosclerosis

Current atherosclerosis reports, 2015-10, Vol.17 (10), p.60-60, Article 60

2015

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Robust passive and active efflux of cellular cholesterol to a designer functional mimic of high density lipoprotein

Journal of lipid research, 2015-05, Vol.56 (5), p.972-985

2015

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A novel approach to measuring macrophage-specific reverse cholesterol transport in vivo in humans

Journal of lipid research, 2017-04, Vol.58 (4), p.752-762

2017

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Increased Atherosclerosis in Mice Lacking Apolipoprotein A-I Attributable to Both Impaired Reverse Cholesterol Transport and Increased Inflammation

Circulation research, 2005-10, Vol.97 (8), p.763-771

2005

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Hepatic Proprotein Convertases Modulate HDL Metabolism

Cell metabolism, 2007-08, Vol.6 (2), p.129-136

2007

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Overexpression and deletion of phospholipid transfer protein reduce HDL mass and cholesterol efflux capacity but not macrophage reverse cholesterol transport

Journal of lipid research, 2017-04, Vol.58 (4), p.731-741

2017

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Inhibition of endothelial lipase causes increased HDL cholesterol levels in vivo

The Journal of clinical investigation, 2003-02, Vol.111 (3), p.357-362

2003

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Modulation of HDL metabolism by the niacin receptor GPR109A in mouse hepatocytes

Biochemical pharmacology, 2010-11, Vol.80 (9), p.1450-1457

2010

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Effects of Therapeutic Lifestyle Change diets high and low in dietary fish-derived FAs on lipoprotein metabolism in middle-aged and elderly subjects

Journal of lipid research, 2012-09, Vol.53 (9), p.1958-1967

2012

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A functional, genome-wide evaluation of liposensitive yeast identifies the "ARE2 required for viability" (ARV1) gene product as a major component of eukaryotic fatty acid resistance

The Journal of biological chemistry, 2014-02, Vol.289 (7), p.4417-4431

2014

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Pathways by which reconstituted high-density lipoprotein mobilizes free cholesterol from whole body and from macrophages

Arteriosclerosis, thrombosis, and vascular biology, 2010-03, Vol.30 (3), p.526-532

2010

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LDL-Cholesterol Reduction by ANGPTL3 Inhibition in Mice Is Dependent on Endothelial Lipase

Endothelial lipase mediates efficient lipolysis of triglyceride-rich lipoproteins

Herbivorous turtle ants obtain essential nutrients from a conserved nitrogen-recycling gut microbiome

A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels

Hepatic protein phosphatase 1 regulatory subunit 3B (Ppp1r3b) promotes hepatic glycogen synthesis and thereby regulates fasting energy homeostasis

Macrophage Sortilin Promotes LDL Uptake, Foam Cell Formation, and Atherosclerosis

Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism

TRIB1 regulates LDL metabolism through CEBPα-mediated effects on the LDL receptor in hepatocytes

Indirect and mitigated effects of pulsed resources on the population dynamics of a northern rodent

ILRUN, a Human Plasma Lipid GWAS Locus, Regulates Lipoprotein Metabolism in Mice

Functional Analysis and Transcriptomic Profiling of iPSC-Derived Macrophages and Their Application in Modeling Mendelian Disease

Reduced sterol regulatory element‐binding protein (SREBP) processing through site‐1 protease (S1P) inhibition alters oligodendrocyte differentiation in vitro

Determining hepatic triglyceride production in mice: comparison of poloxamer 407 with Triton WR-1339

ApoA-I-Directed Therapies for the Management of Atherosclerosis

Robust passive and active efflux of cellular cholesterol to a designer functional mimic of high density lipoprotein

A novel approach to measuring macrophage-specific reverse cholesterol transport in vivo in humans

Increased Atherosclerosis in Mice Lacking Apolipoprotein A-I Attributable to Both Impaired Reverse Cholesterol Transport and Increased Inflammation

Hepatic Proprotein Convertases Modulate HDL Metabolism

Overexpression and deletion of phospholipid transfer protein reduce HDL mass and cholesterol efflux capacity but not macrophage reverse cholesterol transport

Inhibition of endothelial lipase causes increased HDL cholesterol levels in vivo

Modulation of HDL metabolism by the niacin receptor GPR109A in mouse hepatocytes

Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents

Effects of Therapeutic Lifestyle Change diets high and low in dietary fish-derived FAs on lipoprotein metabolism in middle-aged and elderly subjects

A functional, genome-wide evaluation of liposensitive yeast identifies the "ARE2 required for viability" (ARV1) gene product as a major component of eukaryotic fatty acid resistance

Pathways by which reconstituted high-density lipoprotein mobilizes free cholesterol from whole body and from macrophages

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