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Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cells

Cancer research (Chicago, Ill.), 2006-02, Vol.66 (3), p.1630-1639

2006

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The Effects of the Novel, Reversible Epidermal Growth Factor Receptor/ErbB-2 Tyrosine Kinase Inhibitor, GW2016, on the Growth of Human Normal and Tumor-derived Cell Lines in Vitro and in Vivo

Molecular cancer therapeutics, 2001-12, Vol.1 (2), p.85-94

2001

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The characterization of novel, dual ErbB-2/EGFR, tyrosine kinase inhibitors: Potential therapy for cancer

Cancer research (Chicago, Ill.), 2001-10, Vol.61 (19), p.7196-7203

2001

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Synthesis and stereochemical effects of pyrrolidinyl-acetylenic thieno[3,2- d]pyrimidines as EGFR and ErbB-2 inhibitors

Bioorganic & medicinal chemistry letters, 2009, Vol.19 (1), p.21-26

2009

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Discovery and Biological Evaluation of Potent Dual ErbB-2/EGFR Tyrosine Kinase Inhibitors: 6-Thiazolylquinazolines

Bioorganic & medicinal chemistry letters, 2003-02, Vol.13 (4), p.637-640

2003

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In vivo and in vitro metabolism of 5-deazaacyclotetrahydrofolate, an acyclic tetrahydrofolate analogue

Cancer research (Chicago, Ill.), 1990-06, Vol.50 (11), p.3207-3211

1990

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In vivo antitumor activity and metabolism of a series of 5-deazaacyclotetrahydrofolate (5-DACTHF) analogues

Biochemical pharmacology, 1992-04, Vol.43 (7), p.1627-1634

1992

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Distribution and metabolism of calcium leucovorin in normal and tumor tissue

Advances in experimental medicine and biology, 1988, Vol.244, p.25

1988

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Griffithsin carrageenan fast dissolving inserts prevent SHIV HSV-2 and HPV infections in vivo

Nature communications, 2018-09, Vol.9 (1), p.3881-9, Article 3881

2018

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Mutability dynamics of an emergent single stranded DNA virus in a naïve host

PloS one, 2014, Vol.9 (1), p.e85370-e85370

2014

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Increased Helicobacter pylori-associated gastric cancer risk in the Andean region of Colombia is mediated by spermine oxidase

Oncogene, 2015-06, Vol.34 (26), p.3429-3440

2015

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Dietary Arginine Regulates Severity of Experimental Colitis and Affects the Colonic Microbiome

Frontiers in cellular and infection microbiology, 2019-03, Vol.9, p.66

2019

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Griffithsin and Carrageenan Combination To Target Herpes Simplex Virus 2 and Human Papillomavirus

Antimicrobial agents and chemotherapy, 2015-12, Vol.59 (12), p.7290-7298

2015

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Eosinophils are part of the granulocyte response in tuberculosis and promote host resistance in mice

The Journal of experimental medicine, 2021-10, Vol.218 (10)

2021

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Utilizing a TLR5-Adjuvanted Cytomegalovirus as a Lentiviral Vaccine in the Nonhuman Primate Model for AIDS

PloS one, 2016-05, Vol.11 (5), p.e0155629-e0155629

2016

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Polyamines Impair Immunity to Helicobacter pylori by Inhibiting L-Arginine Uptake Required for Nitric Oxide Production

Gastroenterology (New York, N.Y. 1943), 2010-11, Vol.139 (5), p.1686-1698.e6

2010

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Neural deficits contribute to respiratory insufficiency in Pompe disease

Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (23), p.9419-9424

2009

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α-Difluoromethylornithine reduces gastric carcinogenesis by causing mutations in Helicobacter pylori cagY

Proceedings of the National Academy of Sciences - PNAS, 2019-03, Vol.116 (11), p.5077-5085

2019

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Defective positioning in granulomas but not lung-homing limits CD4 T-cell interactions with Mycobacterium tuberculosis-infected macrophages in rhesus macaques

Mucosal immunology, 2018-03, Vol.11 (2), p.462-473

2018

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Evidence for Feedback Regulation Following Cholesterol Lowering Therapy in a Prostate Cancer Xenograft Model

The Prostate, 2017-04, Vol.77 (5), p.446-457

2017

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AZD8055 Is a Potent, Selective, and Orally Bioavailable ATP-Competitive Mammalian Target of Rapamycin Kinase Inhibitor with In vitro and In vivo Antitumor Activity

Cancer research (Chicago, Ill.), 2010, Vol.70 (1), p.288-298

2010

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Autologous transplants of Adipose-Derived Adult Stromal (ADAS) cells afford dopaminergic neuroprotection in a model of Parkinson's disease

Experimental neurology, 2008-03, Vol.210 (1), p.14-29

2008

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Limited dissemination and shedding of the UL128 complex-intact, UL/b'-defective rhesus cytomegalovirus strain 180.92

Journal of virology, 2014-08, Vol.88 (16), p.9310-9320

2014

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Expanded therapeutic potential in activity space of next-generation 5-nitroimidazole antimicrobials with broad structural diversity

Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (43), p.17564-17569

2013

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Blocking Soluble Tumor Necrosis Factor Signaling with Dominant-Negative Tumor Necrosis Factor Inhibitor Attenuates Loss of Dopaminergic Neurons in Models of Parkinson's Disease

The Journal of neuroscience, 2006-09, Vol.26 (37), p.9365-9375

2006

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Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cells

The Effects of the Novel, Reversible Epidermal Growth Factor Receptor/ErbB-2 Tyrosine Kinase Inhibitor, GW2016, on the Growth of Human Normal and Tumor-derived Cell Lines in Vitro and in Vivo

The characterization of novel, dual ErbB-2/EGFR, tyrosine kinase inhibitors: Potential therapy for cancer

Synthesis and stereochemical effects of pyrrolidinyl-acetylenic thieno[3,2- d]pyrimidines as EGFR and ErbB-2 inhibitors

Discovery and Biological Evaluation of Potent Dual ErbB-2/EGFR Tyrosine Kinase Inhibitors: 6-Thiazolylquinazolines

In vivo and in vitro metabolism of 5-deazaacyclotetrahydrofolate, an acyclic tetrahydrofolate analogue

In vivo antitumor activity and metabolism of a series of 5-deazaacyclotetrahydrofolate (5-DACTHF) analogues

Distribution and metabolism of calcium leucovorin in normal and tumor tissue

Griffithsin carrageenan fast dissolving inserts prevent SHIV HSV-2 and HPV infections in vivo

Mutability dynamics of an emergent single stranded DNA virus in a naïve host

Increased Helicobacter pylori-associated gastric cancer risk in the Andean region of Colombia is mediated by spermine oxidase

Dietary Arginine Regulates Severity of Experimental Colitis and Affects the Colonic Microbiome

Griffithsin and Carrageenan Combination To Target Herpes Simplex Virus 2 and Human Papillomavirus

Eosinophils are part of the granulocyte response in tuberculosis and promote host resistance in mice

Utilizing a TLR5-Adjuvanted Cytomegalovirus as a Lentiviral Vaccine in the Nonhuman Primate Model for AIDS

Polyamines Impair Immunity to Helicobacter pylori by Inhibiting L-Arginine Uptake Required for Nitric Oxide Production

Neural deficits contribute to respiratory insufficiency in Pompe disease

α-Difluoromethylornithine reduces gastric carcinogenesis by causing mutations in Helicobacter pylori cagY

Defective positioning in granulomas but not lung-homing limits CD4 T-cell interactions with Mycobacterium tuberculosis-infected macrophages in rhesus macaques

Evidence for Feedback Regulation Following Cholesterol Lowering Therapy in a Prostate Cancer Xenograft Model

AZD8055 Is a Potent, Selective, and Orally Bioavailable ATP-Competitive Mammalian Target of Rapamycin Kinase Inhibitor with In vitro and In vivo Antitumor Activity

Autologous transplants of Adipose-Derived Adult Stromal (ADAS) cells afford dopaminergic neuroprotection in a model of Parkinson's disease

Limited dissemination and shedding of the UL128 complex-intact, UL/b'-defective rhesus cytomegalovirus strain 180.92

Expanded therapeutic potential in activity space of next-generation 5-nitroimidazole antimicrobials with broad structural diversity

Blocking Soluble Tumor Necrosis Factor Signaling with Dominant-Negative Tumor Necrosis Factor Inhibitor Attenuates Loss of Dopaminergic Neurons in Models of Parkinson's Disease

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