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Lipids Reprogram Metabolism to Become a Major Carbon Source for Histone Acetylation

Cell reports (Cambridge), 2016-11, Vol.17 (6), p.1463-1472

2016

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The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase

Cell metabolism, 2018-06, Vol.27 (6), p.1281-1293.e7

2018

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Oxidative Stress and Covalent Modification of Protein with Bioactive Aldehydes

The Journal of biological chemistry, 2008-08, Vol.283 (32), p.21837-21841

2008

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A Quantitative Map of the Liver Mitochondrial Phosphoproteome Reveals Posttranslational Control of Ketogenesis

Cell metabolism, 2012-11, Vol.16 (5), p.672-683

2012

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The Acetyl Group Buffering Action of Carnitine Acetyltransferase Offsets Macronutrient-Induced Lysine Acetylation of Mitochondrial Proteins

Cell reports (Cambridge), 2016-01, Vol.14 (2), p.243-254

2016

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Disruption of Acetyl-Lysine Turnover in Muscle Mitochondria Promotes Insulin Resistance and Redox Stress without Overt Respiratory Dysfunction

Cell metabolism, 2020-01, Vol.31 (1), p.131-147.e11

2020

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Ablation of Sirtuin5 in the postnatal mouse heart results in protein succinylation and normal survival in response to chronic pressure overload

The Journal of biological chemistry, 2018-07, Vol.293 (27), p.10630-10645

2018

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Remodeling of the Acetylproteome by SIRT3 Manipulation Fails to Affect Insulin Secretion or β Cell Metabolism in the Absence of Overnutrition

Cell reports (Cambridge), 2018-07, Vol.24 (1), p.209-223.e6

2018

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Respiratory Phenomics across Multiple Models of Protein Hyperacylation in Cardiac Mitochondria Reveals a Marginal Impact on Bioenergetics

Cell reports (Cambridge), 2019-02, Vol.26 (6), p.1557-1572.e8

2019

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HGFAC is a ChREBP-regulated hepatokine that enhances glucose and lipid homeostasis

JCI insight, 2023-01, Vol.8 (1)

2023

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SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion

Cell metabolism, 2017-04, Vol.25 (4), p.838-855.e15

2017

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Extreme Acetylation of the Cardiac Mitochondrial Proteome Does Not Promote Heart Failure

Circulation research, 2020-09, Vol.127 (8), p.1094-1108

2020

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Pyruvate-supported flux through medium-chain ketothiolase promotes mitochondrial lipid tolerance in cardiac and skeletal muscles

Cell metabolism, 2023-06, Vol.35 (6), p.1038-1056.e8

2023

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Ketone flux through BDH1 supports metabolic remodeling of skeletal and cardiac muscles in response to intermittent time-restricted feeding

Cell metabolism, 2024-02, Vol.36 (2), p.422-437.e8

2024

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Carbonylation of adipose proteins in obesity and insulin resistance: identification of adipocyte fatty acid-binding protein as a cellular target of 4-hydroxynonenal

Molecular & cellular proteomics, 2007-04, Vol.6 (4), p.624-637

2007

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Chronic caloric restriction maintains a youthful phosphoproteome in aged skeletal muscle

Mechanisms of ageing and development, 2021-04, Vol.195, p.111443-111443, Article 111443

2021

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Deglutarylation of glutaryl-CoA dehydrogenase by deacylating enzyme SIRT5 promotes lysine oxidation in mice

The Journal of biological chemistry, 2022-04, Vol.298 (4), p.101723-101723, Article 101723

2022

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Quantification of Mitochondrial Acetylation Dynamics Highlights Prominent Sites of Metabolic Regulation

The Journal of biological chemistry, 2013-09, Vol.288 (36), p.26209-26219

2013

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Downregulation of Adipose Glutathione S-Transferase A4 Leads to Increased Protein Carbonylation, Oxidative Stress, and Mitochondrial Dysfunction

Diabetes (New York, N.Y.), 2010-05, Vol.59 (5), p.1132-1142

2010

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Phosphoproteomics for the Masses

ACS chemical biology, 2010-01, Vol.5 (1), p.105-119

2010

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A resource of targeted mutant mouse lines for 5,061 genes

Nature genetics, 2021-04, Vol.53 (4), p.416-419

2021

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Mitochondrial DNA Variant in COX1 Subunit Significantly Alters Energy Metabolism of Geographically Divergent Wild Isolates in Caenorhabditis elegans

Journal of molecular biology, 2014-05, Vol.426 (11), p.2199-2216

2014

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X‐ray crystallographic analysis of adipocyte fatty acid binding protein (aP2) modified with 4‐hydroxy‐2‐nonenal

Protein science, 2010-08, Vol.19 (8), p.1480-1489

2010

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Genome-wide screening reveals the genetic basis of mammalian embryonic eye development

BMC biology, 2023-02, Vol.21 (1), p.22-22, Article 22

2023

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Disruption of STIM1-mediated Ca 2+ sensing and energy metabolism in adult skeletal muscle compromises exercise tolerance, proteostasis, and lean mass

Molecular metabolism (Germany), 2022-03, Vol.57, p.101429

2022

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Lipids Reprogram Metabolism to Become a Major Carbon Source for Histone Acetylation

The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase

Oxidative Stress and Covalent Modification of Protein with Bioactive Aldehydes

A Quantitative Map of the Liver Mitochondrial Phosphoproteome Reveals Posttranslational Control of Ketogenesis

The Acetyl Group Buffering Action of Carnitine Acetyltransferase Offsets Macronutrient-Induced Lysine Acetylation of Mitochondrial Proteins

Disruption of Acetyl-Lysine Turnover in Muscle Mitochondria Promotes Insulin Resistance and Redox Stress without Overt Respiratory Dysfunction

Ablation of Sirtuin5 in the postnatal mouse heart results in protein succinylation and normal survival in response to chronic pressure overload

Remodeling of the Acetylproteome by SIRT3 Manipulation Fails to Affect Insulin Secretion or β Cell Metabolism in the Absence of Overnutrition

Respiratory Phenomics across Multiple Models of Protein Hyperacylation in Cardiac Mitochondria Reveals a Marginal Impact on Bioenergetics

HGFAC is a ChREBP-regulated hepatokine that enhances glucose and lipid homeostasis

SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion

Extreme Acetylation of the Cardiac Mitochondrial Proteome Does Not Promote Heart Failure

Pyruvate-supported flux through medium-chain ketothiolase promotes mitochondrial lipid tolerance in cardiac and skeletal muscles

Ketone flux through BDH1 supports metabolic remodeling of skeletal and cardiac muscles in response to intermittent time-restricted feeding

Carbonylation of adipose proteins in obesity and insulin resistance: identification of adipocyte fatty acid-binding protein as a cellular target of 4-hydroxynonenal

Chronic caloric restriction maintains a youthful phosphoproteome in aged skeletal muscle

Deglutarylation of glutaryl-CoA dehydrogenase by deacylating enzyme SIRT5 promotes lysine oxidation in mice

Quantification of Mitochondrial Acetylation Dynamics Highlights Prominent Sites of Metabolic Regulation

Downregulation of Adipose Glutathione S-Transferase A4 Leads to Increased Protein Carbonylation, Oxidative Stress, and Mitochondrial Dysfunction

Phosphoproteomics for the Masses

A resource of targeted mutant mouse lines for 5,061 genes

Mitochondrial DNA Variant in COX1 Subunit Significantly Alters Energy Metabolism of Geographically Divergent Wild Isolates in Caenorhabditis elegans

X‐ray crystallographic analysis of adipocyte fatty acid binding protein (aP2) modified with 4‐hydroxy‐2‐nonenal

Genome-wide screening reveals the genetic basis of mammalian embryonic eye development

Disruption of STIM1-mediated Ca 2+ sensing and energy metabolism in adult skeletal muscle compromises exercise tolerance, proteostasis, and lean mass

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