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3-2-1: Structural insights from stepwise shrinkage of a three-helix Fc-binding domain to a single helix

Protein engineering, design and selection, 2017-09, Vol.30 (9), p.619-625

2017

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Identification of a Helical Segment within the Intrinsically Disordered Region of the PCSK9 Prodomain

Journal of molecular biology, 2019-03, Vol.431 (5), p.885-903

2019

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A Novel Exosite on Coagulation Factor VIIa and Its Molecular Interactions with a New Class of Peptide Inhibitors

Biochemistry (Easton), 2001-08, Vol.40 (32), p.9522-9531

2001

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X-ray structure of glial cell-derived neurotrophic factor at 1.9 Å resolution and implications for receptor binding

Nature structural biology, 1997-06, Vol.4 (6), p.435-438

1997

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Aspartate Isomerization in the Complementarity-Determining Regions of Two Closely Related Monoclonal Antibodies

Biochemistry (Easton), 2007-02, Vol.46 (6), p.1534-1544

2007

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Function Blocking Antibodies to Neuropilin-1 Generated from a Designed Human Synthetic Antibody Phage Library

Journal of molecular biology, 2007-02, Vol.366 (3), p.815-829

2007

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Phage-displayed Antibody Libraries of Synthetic Heavy Chain Complementarity Determining Regions

Journal of molecular biology, 2004-04, Vol.338 (2), p.299-310

2004

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Tissue Expression, Protease Specificity, and Kunitz Domain Functions of Hepatocyte Growth Factor Activator Inhibitor-1B (HAI-1B), a New Splice Variant of HAI-1

The Journal of biological chemistry, 2003-09, Vol.278 (38), p.36341-36349

2003

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Peptide exosite inhibitors of factor VIIa as anticoagulants

Nature (London), 2000-03, Vol.404 (6777), p.465-470

2000

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Structural and Functional Basis of the Serine Protease-like Hepatocyte Growth Factor β-Chain in Met Binding and Signaling

The Journal of biological chemistry, 2004-09, Vol.279 (38), p.39915-39924

2004

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Conformational Lability in Serine Protease Active Sites: Structures of Hepatocyte Growth Factor Activator (HGFA) Alone and with the Inhibitory Domain from HGFA Inhibitor-1B

Journal of molecular biology, 2005-03, Vol.346 (5), p.1335-1349

2005

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X-ray crystal structure of the protease inhibitor domain of Alzheimer's amyloid .beta.-protein precursor

Biochemistry (Easton), 1990-10, Vol.29 (43), p.10018-10022

1990

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IL-1H, AN INTERLEUKIN 1-RELATED PROTEIN THAT BINDS IL-18 RECEPTOR/IL-1Rrp

Cytokine (Philadelphia, Pa.), 2001-01, Vol.13 (1), p.1-7

2001

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Engineering Exosite Peptides for Complete Inhibition of Factor VIIa Using a Protease Switch with Substrate Phage

The Journal of biological chemistry, 2003-06, Vol.278 (24), p.21823-21830

2003

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Convergent Recognition of the IgE Binding Site on the High-Affinity IgE Receptor

Structure (London), 2004-07, Vol.12 (7), p.1289-1301

2004

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Cyclic RGD peptide analogues as antiplatelet antithrombotics

Journal of medicinal chemistry, 1992-05, Vol.35 (11), p.2040-2048

1992

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X-ray structures of fragments from binding and nonbinding versions of a humanized anti-CD18 antibody: Structural indications of the key role of VH residues 59 to 65

Proteins, structure, function, and bioinformatics, 1994-01, Vol.18 (1), p.49-62

1994

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Antigen binding thermodynamics and antiproliferative effects of chimeric and humanized anti-p185HER2 antibody Fab fragments

Biochemistry (Easton), 1992-06, Vol.31 (24), p.5434-5441

1992

Volltextzugriff (PDF)

Variability of conformations at crystal contacts in BPTI represent true low-energy structures: Correspondence among lattice packing and molecular dynamics structures

Proteins, structure, function, and bioinformatics, 1992-09, Vol.14 (1), p.65-74

1992

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X-ray structure of human relaxin at 1.5 Å : comparison to insulin and implications for receptor binding determinants

Journal of molecular biology, 1991-09, Vol.221 (1), p.15-21

1991

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Framework selection can influence pharmacokinetics of a humanized therapeutic antibody through differences in molecule charge

mAbs, 2014-09, Vol.6 (5), p.1255-1264

2014

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3-2-1: Structural insights from stepwise shrinkage of a three-helix Fc-binding domain to a single helix

Identification of a Helical Segment within the Intrinsically Disordered Region of the PCSK9 Prodomain

A Novel Exosite on Coagulation Factor VIIa and Its Molecular Interactions with a New Class of Peptide Inhibitors

X-ray structure of glial cell-derived neurotrophic factor at 1.9 Å resolution and implications for receptor binding

Aspartate Isomerization in the Complementarity-Determining Regions of Two Closely Related Monoclonal Antibodies

Function Blocking Antibodies to Neuropilin-1 Generated from a Designed Human Synthetic Antibody Phage Library

Phage-displayed Antibody Libraries of Synthetic Heavy Chain Complementarity Determining Regions

Tissue Expression, Protease Specificity, and Kunitz Domain Functions of Hepatocyte Growth Factor Activator Inhibitor-1B (HAI-1B), a New Splice Variant of HAI-1

Peptide exosite inhibitors of factor VIIa as anticoagulants

Structural and Functional Basis of the Serine Protease-like Hepatocyte Growth Factor β-Chain in Met Binding and Signaling

Conformational Lability in Serine Protease Active Sites: Structures of Hepatocyte Growth Factor Activator (HGFA) Alone and with the Inhibitory Domain from HGFA Inhibitor-1B

X-ray crystal structure of the protease inhibitor domain of Alzheimer's amyloid .beta.-protein precursor

IL-1H, AN INTERLEUKIN 1-RELATED PROTEIN THAT BINDS IL-18 RECEPTOR/IL-1Rrp

Engineering Exosite Peptides for Complete Inhibition of Factor VIIa Using a Protease Switch with Substrate Phage

Convergent Recognition of the IgE Binding Site on the High-Affinity IgE Receptor

Cyclic RGD peptide analogues as antiplatelet antithrombotics

X-ray structures of fragments from binding and nonbinding versions of a humanized anti-CD18 antibody: Structural indications of the key role of VH residues 59 to 65

Antigen binding thermodynamics and antiproliferative effects of chimeric and humanized anti-p185HER2 antibody Fab fragments

Variability of conformations at crystal contacts in BPTI represent true low-energy structures: Correspondence among lattice packing and molecular dynamics structures

X-ray structure of human relaxin at 1.5 Å : comparison to insulin and implications for receptor binding determinants

Framework selection can influence pharmacokinetics of a humanized therapeutic antibody through differences in molecule charge

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