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AMPK-Dependent Degradation of TXNIP upon Energy Stress Leads to Enhanced Glucose Uptake via GLUT1

Molecular cell, 2013-03, Vol.49 (6), p.1167-1175

2013

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The Tumor Suppressor LKB1 Kinase Directly Activates AMP-Activated Kinase and Regulates Apoptosis in Response to Energy Stress

Proceedings of the National Academy of Sciences - PNAS, 2004-03, Vol.101 (10), p.3329-3335

2004

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Identification of the Tuberous Sclerosis Complex-2 Tumor Suppressor Gene Product Tuberin as a Target of the Phosphoinositide 3-Kinase/Akt Pathway

Molecular cell, 2002-07, Vol.10 (1), p.151-162

2002

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Determination of protease cleavage site motifs using mixture-based oriented peptide libraries

Nature biotechnology, 2001-07, Vol.19 (7), p.661-667

2001

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A motif-based profile scanning approach for genome-wide prediction of signaling pathways

Nature biotechnology, 2001-04, Vol.19 (4), p.348-353

2001

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Large-Scale Characterization of HeLa Cell Nuclear Phosphoproteins

Proceedings of the National Academy of Sciences - PNAS, 2004-08, Vol.101 (33), p.12130-12135

2004

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Affinity-Driven Peptide Selection of an NFAT Inhibitor More Selective Than Cyclosporin A

Science (American Association for the Advancement of Science), 1999-09, Vol.285 (5436), p.2129-2133

1999

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The Crohn's Disease Protein, NOD2, Requires RIP2 in Order to Induce Ubiquitinylation of a Novel Site on NEMO

Current biology, 2004-12, Vol.14 (24), p.2217-2227

2004

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The Mycobacterium tuberculosis serine/threonine kinases PknA and PknB: substrate identification and regulation of cell shape

Genes & development, 2005-07, Vol.19 (14), p.1692-1704

2005

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A Fluorescent Reporter of AMPK Activity and Cellular Energy Stress

Cell metabolism, 2011-04, Vol.13 (4), p.476-486

2011

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The Molecular Basis for Phosphodependent Substrate Targeting and Regulation of Plks by the Polo-Box Domain

Cell, 2003-10, Vol.115 (1), p.83-95

2003

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p85α SH2 Domain Phosphorylation by IKK Promotes Feedback Inhibition of PI3K and Akt in Response to Cellular Starvation

Molecular cell, 2012-03, Vol.45 (6), p.719-730

2012

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Phosphoproteomic Analysis Identifies Grb10 as an mTORC1 Substrate That Negatively Regulates Insulin Signaling

Science (American Association for the Advancement of Science), 2011-06, Vol.332 (6035), p.1322-1326

2011

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Mitotic MELK-eIF4B signaling controls protein synthesis and tumor cell survival

Proceedings of the National Academy of Sciences - PNAS, 2016-08, Vol.113 (35), p.9810-9815

2016

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Ubiquitination of K-Ras enhances activation and facilitates binding to select downstream effectors

Science signaling, 2011-03, Vol.4 (163), p.ra13

2011

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Recognition of Unique Carboxyl-Terminal Motifs by Distinct PDZ Domains

Science (American Association for the Advancement of Science), 1997-01, Vol.275 (5296), p.73-77

1997

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Phosphorylation-dependent substrate selectivity of protein kinase B (AKT1)

The Journal of biological chemistry, 2020-06, Vol.295 (24), p.8120-8134

2020

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The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor

Nature structural & molecular biology, 2004-01, Vol.11 (1), p.60-66

2004

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TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins

The EMBO journal, 2000-12, Vol.19 (24), p.6778-6791

2000

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Peptide and Protein Library Screening Defines Optimal Substrate Motifs for AKT/PKB

The Journal of biological chemistry, 2000-11, Vol.275 (46), p.36108-36115

2000

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The PX domains of p47phox and p40phox bind to lipid products of PI(3)K

Nature cell biology, 2001-07, Vol.3 (7), p.675-678

2001

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bacterial symbiont is converted from an inedible producer of beneficial molecules into food by a single mutation in the gacA gene

Proceedings of the National Academy of Sciences - PNAS, 2013-09, Vol.110 (36), p.14528-14533

2013

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Development of a high-throughput assay for identifying inhibitors of TBK1 and IKKε

PloS one, 2012-07, Vol.7 (7), p.e41494-e41494

2012

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Transformation of Chicken Cells by the Gene Encoding the Catalytic Subunit of PI 3-Kinase

Science (American Association for the Advancement of Science), 1997-06, Vol.276 (5320), p.1848-1850

1997

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TTBK2 kinase substrate specificity and the impact of spinocerebellar-ataxia-causing mutations on expression, activity, localization and development

Biochemical journal, 2011-07, Vol.437 (1), p.157-167

2011

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AMPK-Dependent Degradation of TXNIP upon Energy Stress Leads to Enhanced Glucose Uptake via GLUT1

The Tumor Suppressor LKB1 Kinase Directly Activates AMP-Activated Kinase and Regulates Apoptosis in Response to Energy Stress

Identification of the Tuberous Sclerosis Complex-2 Tumor Suppressor Gene Product Tuberin as a Target of the Phosphoinositide 3-Kinase/Akt Pathway

Determination of protease cleavage site motifs using mixture-based oriented peptide libraries

A motif-based profile scanning approach for genome-wide prediction of signaling pathways

Large-Scale Characterization of HeLa Cell Nuclear Phosphoproteins

Affinity-Driven Peptide Selection of an NFAT Inhibitor More Selective Than Cyclosporin A

The Crohn's Disease Protein, NOD2, Requires RIP2 in Order to Induce Ubiquitinylation of a Novel Site on NEMO

The Mycobacterium tuberculosis serine/threonine kinases PknA and PknB: substrate identification and regulation of cell shape

A Fluorescent Reporter of AMPK Activity and Cellular Energy Stress

The Molecular Basis for Phosphodependent Substrate Targeting and Regulation of Plks by the Polo-Box Domain

p85α SH2 Domain Phosphorylation by IKK Promotes Feedback Inhibition of PI3K and Akt in Response to Cellular Starvation

Phosphoproteomic Analysis Identifies Grb10 as an mTORC1 Substrate That Negatively Regulates Insulin Signaling

Mitotic MELK-eIF4B signaling controls protein synthesis and tumor cell survival

Ubiquitination of K-Ras enhances activation and facilitates binding to select downstream effectors

Recognition of Unique Carboxyl-Terminal Motifs by Distinct PDZ Domains

Phosphorylation-dependent substrate selectivity of protein kinase B (AKT1)

The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor

TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins

Peptide and Protein Library Screening Defines Optimal Substrate Motifs for AKT/PKB

The PX domains of p47phox and p40phox bind to lipid products of PI(3)K

bacterial symbiont is converted from an inedible producer of beneficial molecules into food by a single mutation in the gacA gene

Development of a high-throughput assay for identifying inhibitors of TBK1 and IKKε

Transformation of Chicken Cells by the Gene Encoding the Catalytic Subunit of PI 3-Kinase

TTBK2 kinase substrate specificity and the impact of spinocerebellar-ataxia-causing mutations on expression, activity, localization and development

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