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Vascular pathologies in chronic kidney disease: pathophysiological mechanisms and novel therapeutic approaches

Journal of molecular medicine (Berlin, Germany), 2021-03, Vol.99 (3), p.335-348

2021

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Regulation and function of CX3CR1 and its ligand CX3CL1 in kidney disease

Cell and tissue research, 2021-08, Vol.385 (2), p.335-344

2021

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Kidney dendritic cells: fundamental biology and functional roles in health and disease

Nature reviews. Nephrology, 2020-07, Vol.16 (7), p.391

2020

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Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation

Nature immunology, 2008-05, Vol.9 (5), p.558-566

2008

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Liver inflammation abrogates immunological tolerance induced by Kupffer cells

Hepatology (Baltimore, Md.), 2015-07, Vol.62 (1), p.279-291

2015

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Bcl10-controlled Malt1 paracaspase activity is key for the immune suppressive function of regulatory T cells

Nature communications, 2019-05, Vol.10 (1), p.2352-15, Article 2352

2019

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Fully Automated Evaluation of Total Glomerular Number and Capillary Tuft Size in Nephritic Kidneys Using Lightsheet Microscopy

Journal of the American Society of Nephrology, 2017-02, Vol.28 (2), p.452-459

2017

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The JAK-inhibitor ruxolitinib impairs dendritic cell function in vitro and in vivo

Blood, 2013-08, Vol.122 (7), p.1192-1202

2013

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Salt, inflammation, IL‐17 and hypertension

British journal of pharmacology, 2019-06, Vol.176 (12), p.1853-1863

2019

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An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice

Kidney international, 2016-09, Vol.90 (3), p.525-539

2016

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Irf4 -dependent CD103 + CD11b + dendritic cells and the intestinal microbiome regulate monocyte and macrophage activation and intestinal peristalsis in postoperative ileus

Gut, 2017-12, Vol.66 (12), p.2110

2017

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Differential early diagnosis of benign versus malignant lung cancer using systematic pathway flux analysis of peripheral blood leukocytes

Scientific reports, 2022-03, Vol.12 (1), p.5070-5070, Article 5070

2022

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Regulatory T cells use programmed death 1 ligands to directly suppress autoreactive B cells in vivo

Proceedings of the National Academy of Sciences - PNAS, 2012-06, Vol.109 (26), p.10468-10473

2012

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Development and validation of prognostic model for predicting mortality of COVID-19 patients in Wuhan, China

Scientific reports, 2020-12, Vol.10 (1), p.22451-22451, Article 22451

2020

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Immune tolerance against infused FVIII in hemophilia A is mediated by PD-L1+ Tregs

The Journal of clinical investigation, 2022-11, Vol.132 (22), p.1-15

2022

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VEGF-production by CCR2-dependent macrophages contributes to laser-induced choroidal neovascularization

PloS one, 2014-04, Vol.9 (4), p.e94313-e94313

2014

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In Vivo Labeling by CD73 Marks Multipotent Stromal Cells and Highlights Endothelial Heterogeneity in the Bone Marrow Niche

Cell stem cell, 2018-02, Vol.22 (2), p.262-276.e7

2018

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The multifaceted role of the renal mononuclear phagocyte system

Cellular immunology, 2018-08, Vol.330, p.97-104

2018

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Mucosal-associated invariant T cells contribute to suppression of inflammatory myeloid cells in immune-mediated kidney disease

Nature communications, 2023-11, Vol.14 (1), p.7372-7372, Article 7372

2023

Volltextzugriff (PDF)

Rapid protection against viral infections by chemokine-accelerated post-exposure vaccination

Frontiers in immunology, 2024, Vol.15, p.1338499-1338499

2024

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CX3CR1 reduces kidney fibrosis by inhibiting local proliferation of profibrotic macrophages

The Journal of immunology (1950), 2015-02, Vol.194 (4), p.1628-1638

2015

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CX3CR1 is a prerequisite for the development of cardiac hypertrophy and left ventricular dysfunction in mice upon transverse aortic constriction

PloS one, 2021-01, Vol.16 (1), p.e0243788-e0243788

2021

Volltextzugriff (PDF)

Opposing Roles of Dendritic Cell Subsets in Experimental GN

Journal of the American Society of Nephrology, 2018-01, Vol.29 (1), p.138-154

2018

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Renal Denervation Exacerbates LPS- and Antibody-induced Acute Kidney Injury, but Protects from Pyelonephritis in Mice

Journal of the American Society of Nephrology, 2021-10, Vol.32 (10), p.2445-2453

2021

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HIF1A and NFAT5 coordinate Na+-boosted antibacterial defense via enhanced autophagy and autolysosomal targeting

Autophagy, 2019-11, Vol.15 (11), p.1899-1916

2019

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Vascular pathologies in chronic kidney disease: pathophysiological mechanisms and novel therapeutic approaches

Regulation and function of CX3CR1 and its ligand CX3CL1 in kidney disease

Kidney dendritic cells: fundamental biology and functional roles in health and disease

Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation

Liver inflammation abrogates immunological tolerance induced by Kupffer cells

Bcl10-controlled Malt1 paracaspase activity is key for the immune suppressive function of regulatory T cells

Fully Automated Evaluation of Total Glomerular Number and Capillary Tuft Size in Nephritic Kidneys Using Lightsheet Microscopy

The JAK-inhibitor ruxolitinib impairs dendritic cell function in vitro and in vivo

Salt, inflammation, IL‐17 and hypertension

An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice

Irf4 -dependent CD103 + CD11b + dendritic cells and the intestinal microbiome regulate monocyte and macrophage activation and intestinal peristalsis in postoperative ileus

Differential early diagnosis of benign versus malignant lung cancer using systematic pathway flux analysis of peripheral blood leukocytes

Regulatory T cells use programmed death 1 ligands to directly suppress autoreactive B cells in vivo

Development and validation of prognostic model for predicting mortality of COVID-19 patients in Wuhan, China

Immune tolerance against infused FVIII in hemophilia A is mediated by PD-L1+ Tregs

VEGF-production by CCR2-dependent macrophages contributes to laser-induced choroidal neovascularization

In Vivo Labeling by CD73 Marks Multipotent Stromal Cells and Highlights Endothelial Heterogeneity in the Bone Marrow Niche

The multifaceted role of the renal mononuclear phagocyte system

Mucosal-associated invariant T cells contribute to suppression of inflammatory myeloid cells in immune-mediated kidney disease

Rapid protection against viral infections by chemokine-accelerated post-exposure vaccination

CX3CR1 reduces kidney fibrosis by inhibiting local proliferation of profibrotic macrophages

CX3CR1 is a prerequisite for the development of cardiac hypertrophy and left ventricular dysfunction in mice upon transverse aortic constriction

Opposing Roles of Dendritic Cell Subsets in Experimental GN

Renal Denervation Exacerbates LPS- and Antibody-induced Acute Kidney Injury, but Protects from Pyelonephritis in Mice

HIF1A and NFAT5 coordinate Na+-boosted antibacterial defense via enhanced autophagy and autolysosomal targeting

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