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Heterodimerization, Altered Subcellular Localization, and Function of Multiple Zinc Transporters in Viable Cells Using Bimolecular Fluorescence Complementation
The Journal of biological chemistry, 2015-04, Vol.290 (14), p.9050-9063
2015
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In Situ Dimerization of Multiple Wild Type and Mutant Zinc Transporters in Live Cells Using Bimolecular Fluorescence Complementation
The Journal of biological chemistry, 2014-03, Vol.289 (11), p.7275-7292
2014
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The Obligatory Intestinal Folate Transporter PCFT (SLC46A1) Is Regulated by Nuclear Respiratory Factor 1
The Journal of biological chemistry, 2010-10, Vol.285 (44), p.33602-33613
2010
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A Dominant Negative Heterozygous G87R Mutation in the Zinc Transporter, ZnT-2 (SLC30A2), Results in Transient Neonatal Zinc Deficiency
The Journal of biological chemistry, 2012-08, Vol.287 (35), p.29348-29361
2012
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Molecular Basis of Transient Neonatal Zinc Deficiency: NOVEL ZnT2 MUTATIONS DISRUPTING ZINC BINDING AND PERMEATION
The Journal of biological chemistry, 2016-06, Vol.291 (26), p.13546-13559
2016
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Alterations in the Expression of Transcription Factors and the Reduced Folate Carrier as a Novel Mechanism of Antifolate Resistance in Human Leukemia Cells
The Journal of biological chemistry, 2003-03, Vol.278 (11), p.8935-8941
2003
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Reduced Folate Carrier Gene Silencing in Multiple Antifolate-resistant Tumor Cell Lines Is Due to a Simultaneous Loss of Function of Multiple Transcription Factors but Not Promoter Methylation
The Journal of biological chemistry, 2004-01, Vol.279 (1), p.374-384
2004
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Loss of Multidrug Resistance Protein 1 Expression and Folate Efflux Activity Results in a Highly Concentrative Folate Transport in Human Leukemia Cells
The Journal of biological chemistry, 2003-02, Vol.278 (9), p.6680-6686
2003
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Reduced Folate Carrier (RFC) Is Cytotoxic to Cells under Conditions of Severe Folate Deprivation: RFC AS A DOUBLE EDGED SWORD IN FOLATE HOMEOSTASIS
The Journal of biological chemistry, 2008-07, Vol.283 (30), p.20687-20695
2008
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Heterogeneous Nuclear Ribonucleoprotein H1/H2-dependent Unsplicing of Thymidine Phosphorylase Results in Anticancer Drug Resistance
The Journal of biological chemistry, 2011-02, Vol.286 (5), p.3741-3754
2011
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Molecular Basis of Transient Neonatal Zinc Deficiency
The Journal of biological chemistry, 2016-06, Vol.291 (26), p.13546-13559
2016
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Folate deprivation results in the loss of breast cancer resistance protein (BCRP/ABCG2) expression. A role for BCRP in cellular folate homeostasis
The Journal of biological chemistry, 2004-06, Vol.279 (24), p.25527-25534
2004
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The Reduced Folate Carrier (RFC) Is Cytotoxic to Cells under Conditions of Severe Folate Deprivation
The Journal of biological chemistry, 2008-07, Vol.283 (30), p.20687-20695
2008
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The Role of Passive Transbilayer Drug Movement in Multidrug Resistance and Its Modulation
The Journal of biological chemistry, 1996-05, Vol.271 (22), p.12897-12902
1996
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A Structurally Altered Human Reduced Folate Carrier with Increased Folic Acid Transport Mediates a Novel Mechanism of Antifolate Resistance
The Journal of biological chemistry, 1998-11, Vol.273 (46), p.30189-30198
1998
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Competition of Hydrophobic Peptides, Cytotoxic Drugs, and Chemosensitizers on a Common P-glycoprotein Pharmacophore as Revealed by Its ATPase Activity (∗)
The Journal of biological chemistry, 1996-02, Vol.271 (6), p.3163-3171
1996
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Clustering of Mutations in the First Transmembrane Domain of the Human Reduced Folate Carrier in GW1843U89-resistant Leukemia Cells with Impaired Antifolate Transport and Augmented Folate Uptake
The Journal of biological chemistry, 2000-10, Vol.275 (40), p.30855-30863
2000
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A Reduced Folate Carrier Mutation Produces Substrate-dependent Alterations in Carrier Mobility in Murine Leukemia Cells and Methotrexate Resistance with Conservation of Growth in 5-Formyltetrahydrofolate
The Journal of biological chemistry, 1998-04, Vol.273 (14), p.7873-7879
1998
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A Mutated Murine Reduced Folate Carrier (RFC1) with Increased Affinity for Folic Acid, Decreased Affinity for Methotrexate, and an Obligatory Anion Requirement for Transport Function
The Journal of biological chemistry, 1998-07, Vol.273 (30), p.19065-19071
1998
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Functional Reconstitution of P-glycoprotein Reveals an Apparent Near Stoichiometric Drug Transport to ATP Hydrolysis (∗)
The Journal of biological chemistry, 1996-02, Vol.271 (6), p.3172-3178
1996
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Loss of Folic Acid Exporter Function with Markedly Augmented Folate Accumulation in Lipophilic Antifolate-resistant Mammalian Cells
The Journal of biological chemistry, 1997-07, Vol.272 (28), p.17460-17466
1997
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Increased Activity of a Novel Low pH Folate Transporter Associated with Lipophilic Antifolate Resistance in Chinese Hamster Ovary Cells
The Journal of biological chemistry, 1998-04, Vol.273 (14), p.8106-8111
1998
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Folate Deprivation Results in the Loss of Breast Cancer Resistance Protein (BCRP/ABCG2) Expression
The Journal of biological chemistry, 2004-06, Vol.279 (24), p.25527-25534
2004
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Alteration of Mitochondrial Gene Expression and Disruption of Respiratory Function by the Lipophilic Antifolate Pyrimethamine in Mammalian Cells (∗)
The Journal of biological chemistry, 1995-09, Vol.270 (35), p.20668-20676
1995
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Transport of polypeptide ionophores into proteoliposomes reconstituted with rat liver P-glycoprotein
The Journal of biological chemistry, 1994-10, Vol.269 (42), p.26058-26065
1994
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