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Biological impact of mutually exclusive exon switching

PLoS computational biology, 2021-03, Vol.17 (3), p.e1008708-e1008708

2021

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Generating functional protein variants with variational autoencoders

PLoS computational biology, 2021-02, Vol.17 (2), p.e1008736-e1008736

2021

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An analysis of tissue-specific alternative splicing at the protein level

PLoS computational biology, 2020-10, Vol.16 (10), p.e1008287-e1008287

2020

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Analysis of temporal transcription expression profiles reveal links between protein function and developmental stages of Drosophila melanogaster

PLoS computational biology, 2017-10, Vol.13 (10), p.e1005791-e1005791

2017

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Exploring the evolution of novel enzyme functions within structurally defined protein superfamilies

PLoS computational biology, 2012-03, Vol.8 (3), p.e1002403-e1002403

2012

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Alpha Helices Are More Robust to Mutations than Beta Strands

PLoS computational biology, 2016-12, Vol.12 (12), p.e1005242-e1005242

2016

Volltextzugriff (PDF)

Inferring function using patterns of native disorder in proteins

PLoS computational biology, 2007-08, Vol.3 (8), p.e162-e162

2007

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Diversity and distribution of nuclease bacteriocins in bacterial genomes revealed using Hidden Markov Models

PLoS computational biology, 2017-07, Vol.13 (7), p.e1005652-e1005652

2017

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Biases in the experimental annotations of protein function and their effect on our understanding of protein function space

PLoS computational biology, 2013-05, Vol.9 (5), p.e1003063-e1003063

2013

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The complexity of protein interactions unravelled from structural disorder

PLoS computational biology, 2021-01, Vol.17 (1), p.e1008546-e1008546

2021

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Systematic Mapping of Protein Mutational Space by Prolonged Drift Reveals the Deleterious Effects of Seemingly Neutral Mutations

PLoS computational biology, 2015-08, Vol.11 (8), p.e1004421

2015

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Conformational diversity analysis reveals three functional mechanisms in proteins

PLoS computational biology, 2017-02, Vol.13 (2), p.e1005398

2017

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Determining effects of non-synonymous SNPs on protein-protein interactions using supervised and semi-supervised learning

PLoS computational biology, 2014-05, Vol.10 (5), p.e1003592

2014

Volltextzugriff (PDF)

Quantitative profiling of protease specificity

PLoS computational biology, 2021-02, Vol.17 (2), p.e1008101-e1008101

2021

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Global patterns of protein domain gain and loss in superkingdoms

PLoS computational biology, 2014-01, Vol.10 (1), p.e1003452-e1003452

2014

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Exploring the composition of protein-ligand binding sites on a large scale

PLoS computational biology, 2013-11, Vol.9 (11), p.e1003321

2013

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FLORA: a novel method to predict protein function from structure in diverse superfamilies

PLoS computational biology, 2009-08, Vol.5 (8), p.e1000485

2009

Volltextzugriff (PDF)

CATHEDRAL: a fast and effective algorithm to predict folds and domain boundaries from multidomain protein structures

PLoS computational biology, 2007-11, Vol.3 (11), p.e232-e232

2007

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Structural and Energetic Characterization of the Ankyrin Repeat Protein Family

PLoS computational biology, 2015-12, Vol.11 (12), p.e1004659-e1004659

2015

Volltextzugriff (PDF)

An Atlas of Peroxiredoxins Created Using an Active Site Profile-Based Approach to Functionally Relevant Clustering of Proteins

PLoS computational biology, 2017-02, Vol.13 (2), p.e1005284-e1005284

2017

Volltextzugriff (PDF)

Functional Basis of Microorganism Classification

PLoS computational biology, 2015-08, Vol.11 (8), p.e1004472-e1004472

2015

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Polymorphic sites preferentially avoid co-evolving residues in MHC class I proteins

PLoS computational biology, 2018-05, Vol.14 (5), p.e1006188-e1006188

2018

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Recognition of sites of functional specialisation in all known eukaryotic protein kinase families

PLoS computational biology, 2018-02, Vol.14 (2), p.e1005975-e1005975

2018

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Bayesian Top-Down Protein Sequence Alignment with Inferred Position-Specific Gap Penalties

PLoS computational biology, 2016-05, Vol.12 (5), p.e1004936-e1004936

2016

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Exploring fold space preferences of new-born and ancient protein superfamilies

PLoS computational biology, 2013-11, Vol.9 (11), p.e1003325-e1003325

2013

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Biological impact of mutually exclusive exon switching

Generating functional protein variants with variational autoencoders

An analysis of tissue-specific alternative splicing at the protein level

Analysis of temporal transcription expression profiles reveal links between protein function and developmental stages of Drosophila melanogaster

Exploring the evolution of novel enzyme functions within structurally defined protein superfamilies

Alpha Helices Are More Robust to Mutations than Beta Strands

Inferring function using patterns of native disorder in proteins

Diversity and distribution of nuclease bacteriocins in bacterial genomes revealed using Hidden Markov Models

Biases in the experimental annotations of protein function and their effect on our understanding of protein function space

The complexity of protein interactions unravelled from structural disorder

Systematic Mapping of Protein Mutational Space by Prolonged Drift Reveals the Deleterious Effects of Seemingly Neutral Mutations

Conformational diversity analysis reveals three functional mechanisms in proteins

Determining effects of non-synonymous SNPs on protein-protein interactions using supervised and semi-supervised learning

Quantitative profiling of protease specificity

Global patterns of protein domain gain and loss in superkingdoms

Exploring the composition of protein-ligand binding sites on a large scale

FLORA: a novel method to predict protein function from structure in diverse superfamilies

CATHEDRAL: a fast and effective algorithm to predict folds and domain boundaries from multidomain protein structures

Structural and Energetic Characterization of the Ankyrin Repeat Protein Family

An Atlas of Peroxiredoxins Created Using an Active Site Profile-Based Approach to Functionally Relevant Clustering of Proteins

Functional Basis of Microorganism Classification

Polymorphic sites preferentially avoid co-evolving residues in MHC class I proteins

Recognition of sites of functional specialisation in all known eukaryotic protein kinase families

Bayesian Top-Down Protein Sequence Alignment with Inferred Position-Specific Gap Penalties

Exploring fold space preferences of new-born and ancient protein superfamilies

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