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Systematic In Vivo Inactivation of Chromatin-Regulating Enzymes Identifies Setd2 as a Potent Tumor Suppressor in Lung Adenocarcinoma

Cancer research (Chicago, Ill.), 2017-04, Vol.77 (7), p.1719-1729

2017

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The Functional Landscape of Patient-Derived RNF43 Mutations Predicts Sensitivity to Wnt Inhibition

Cancer research (Chicago, Ill.), 2020-12, Vol.80 (24), p.5619-5632

2020

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IDO1 and Kynurenine Pathway Metabolites Activate PI3K-Akt Signaling in the Neoplastic Colon Epithelium to Promote Cancer Cell Proliferation and Inhibit Apoptosis

Cancer research (Chicago, Ill.), 2019-03, Vol.79 (6), p.1138-1150

2019

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Pharmacological Inhibition of the Wnt Acyltransferase PORCN Prevents Growth of WNT-Driven Mammary Cancer

Cancer research (Chicago, Ill.), 2013-01, Vol.73 (2), p.502-507

2013

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Androgen Receptor on the Move: Boarding the Microtubule Expressway to the Nucleus

Cancer research (Chicago, Ill.), 2012-09, Vol.72 (18), p.4611-4615

2012

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Colorectal Carcinomas Containing Hypermethylated MLH1 Promoter and Wild-Type BRAF/KRAS Are Enriched for Targetable Kinase Fusions

Cancer research (Chicago, Ill.), 2019-03, Vol.79 (6), p.1047-1053

2019

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Quantifying Preexisting Resistant and Persister Populations-Response

Cancer research (Chicago, Ill.), 2019-10, Vol.79 (19), p.5122-5122

McClatchy, David M

2019

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Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer

Cancer research (Chicago, Ill.), 2014-04, Vol.74 (8), p.2270-2282

2014

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Dishonorable Discharge: The Oncogenic Roles of Cleaved E-Cadherin Fragments

Cancer research (Chicago, Ill.), 2012-06, Vol.72 (12), p.2917-2923

2012

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Senescence-Associated Exosome Release from Human Prostate Cancer Cells

Cancer research (Chicago, Ill.), 2008-10, Vol.68 (19), p.7864-7871

2008

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Mechanisms of Acquired Resistance to BRAF V600E Inhibition in Colon Cancers Converge on RAF Dimerization and Are Sensitive to Its Inhibition

Cancer research (Chicago, Ill.), 2017-12, Vol.77 (23), p.6513-6523

2017

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CX-4945, an orally bioavailable selective inhibitor of protein kinase CK2, inhibits prosurvival and angiogenic signaling and exhibits antitumor efficacy

Cancer research (Chicago, Ill.), 2010-12, Vol.70 (24), p.10288-10298

2010

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mTORC2 Signaling Drives the Development and Progression of Pancreatic Cancer

Cancer research (Chicago, Ill.), 2016-12, Vol.76 (23), p.6911-6923

2016

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Immune Inhibitory Molecules LAG-3 and PD-1 Synergistically Regulate T-cell Function to Promote Tumoral Immune Escape

Cancer research (Chicago, Ill.), 2012-02, Vol.72 (4), p.917-927

2012

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Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (13), p.3826-3837

2016

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Taxane-Induced Blockade to Nuclear Accumulation of the Androgen Receptor Predicts Clinical Responses in Metastatic Prostate Cancer

Cancer research (Chicago, Ill.), 2011-09, Vol.71 (18), p.6019-6029

2011

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Characterization of Torin2, an ATP-Competitive Inhibitor of mTOR, ATM, and ATR

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8), p.2574-2586

2013

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Mevalonate Pathway Provides Ubiquinone to Maintain Pyrimidine Synthesis and Survival in p53-Deficient Cancer Cells Exposed to Metabolic Stress

Cancer research (Chicago, Ill.), 2020-01, Vol.80 (2), p.189-203

2020

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ERK and p38 MAPK Activities Determine Sensitivity to PI3K/mTOR Inhibition via Regulation of MYC and YAP

Cancer research (Chicago, Ill.), 2016-12, Vol.76 (24), p.7168-7180

2016

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Proteomic Identification of a Direct Role for Cyclin D1 in DNA Damage Repair

Cancer research (Chicago, Ill.), 2012-09, Vol.72 (17), p.4289-4293

2012

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In Situ Tumor Vaccination by Combining Local Radiation and Tumor-Specific Antibody or Immunocytokine Treatments

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (13), p.3929-3941

2016

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Melanoma Proliferation and Chemoresistance Controlled by the DEK Oncogene

Cancer research (Chicago, Ill.), 2009-08, Vol.69 (16), p.6405-6413

2009

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Combination Therapy with Bispecific Antibodies and PD-1 Blockade Enhances the Antitumor Potency of T Cells

Cancer research (Chicago, Ill.), 2017-10, Vol.77 (19), p.5384-5394

2017

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Evolutionary Action Score of TP53 Coding Variants Is Predictive of Platinum Response in Head and Neck Cancer Patients

Cancer research (Chicago, Ill.), 2015-04, Vol.75 (7), p.1205-1215

2015

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An EGFR-ERK-SOX9 Signaling Cascade Links Urothelial Development and Regeneration to Cancer

Cancer research (Chicago, Ill.), 2011-06, Vol.71 (11), p.3812-3821

2011

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Systematic In Vivo Inactivation of Chromatin-Regulating Enzymes Identifies Setd2 as a Potent Tumor Suppressor in Lung Adenocarcinoma

The Functional Landscape of Patient-Derived RNF43 Mutations Predicts Sensitivity to Wnt Inhibition

IDO1 and Kynurenine Pathway Metabolites Activate PI3K-Akt Signaling in the Neoplastic Colon Epithelium to Promote Cancer Cell Proliferation and Inhibit Apoptosis

Pharmacological Inhibition of the Wnt Acyltransferase PORCN Prevents Growth of WNT-Driven Mammary Cancer

Androgen Receptor on the Move: Boarding the Microtubule Expressway to the Nucleus

Colorectal Carcinomas Containing Hypermethylated MLH1 Promoter and Wild-Type BRAF/KRAS Are Enriched for Targetable Kinase Fusions

Quantifying Preexisting Resistant and Persister Populations-Response

Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer

Dishonorable Discharge: The Oncogenic Roles of Cleaved E-Cadherin Fragments

Senescence-Associated Exosome Release from Human Prostate Cancer Cells

Mechanisms of Acquired Resistance to BRAF V600E Inhibition in Colon Cancers Converge on RAF Dimerization and Are Sensitive to Its Inhibition

CX-4945, an orally bioavailable selective inhibitor of protein kinase CK2, inhibits prosurvival and angiogenic signaling and exhibits antitumor efficacy

mTORC2 Signaling Drives the Development and Progression of Pancreatic Cancer

Immune Inhibitory Molecules LAG-3 and PD-1 Synergistically Regulate T-cell Function to Promote Tumoral Immune Escape

Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers

Taxane-Induced Blockade to Nuclear Accumulation of the Androgen Receptor Predicts Clinical Responses in Metastatic Prostate Cancer

Characterization of Torin2, an ATP-Competitive Inhibitor of mTOR, ATM, and ATR

Mevalonate Pathway Provides Ubiquinone to Maintain Pyrimidine Synthesis and Survival in p53-Deficient Cancer Cells Exposed to Metabolic Stress

ERK and p38 MAPK Activities Determine Sensitivity to PI3K/mTOR Inhibition via Regulation of MYC and YAP

Proteomic Identification of a Direct Role for Cyclin D1 in DNA Damage Repair

In Situ Tumor Vaccination by Combining Local Radiation and Tumor-Specific Antibody or Immunocytokine Treatments

Melanoma Proliferation and Chemoresistance Controlled by the DEK Oncogene

Combination Therapy with Bispecific Antibodies and PD-1 Blockade Enhances the Antitumor Potency of T Cells

Evolutionary Action Score of TP53 Coding Variants Is Predictive of Platinum Response in Head and Neck Cancer Patients

An EGFR-ERK-SOX9 Signaling Cascade Links Urothelial Development and Regeneration to Cancer

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