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An insight into synthetic Schiff bases revealing antiproliferative activities in vitro

Bioorganic & medicinal chemistry, 2013-07, Vol.21 (13), p.3648-3666

2013

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Synthesis, structure–activity relationships, and mechanism of action of anti-HIV-1 lamellarin α 20-sulfate analogues

Bioorganic & medicinal chemistry, 2011-12, Vol.19 (24), p.7541-7550

2011

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Synthesis and molecular docking of 1,2,3-triazole-based sulfonamides as aromatase inhibitors

Bioorganic & medicinal chemistry, 2015-07, Vol.23 (13), p.3472-3480

2015

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Medicinal attributes of pyrazolo[3,4-d]pyrimidines: A review

Bioorganic & medicinal chemistry, 2013-09, Vol.21 (18), p.5657-5668

2013

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Discovery of a new class of valosine containing protein (VCP/P97) inhibitors for the treatment of colorectal cancer

Bioorganic & medicinal chemistry, 2022-11, Vol.74, p.117050-117050, Article 117050

2022

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Quinazolines and quinazolinones as ubiquitous structural fragments in medicinal chemistry: An update on the development of synthetic methods and pharmacological diversification

Bioorganic & medicinal chemistry, 2016-06, Vol.24 (11), p.2361-2381

2016

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Synthesis of novel indole-thiazolidinone hybrid structures as promising scaffold with anticancer potential

Bioorganic & medicinal chemistry, 2021-11, Vol.50, p.116453, Article 116453

2021

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Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisinin

Bioorganic & medicinal chemistry, 2018-07, Vol.26 (12), p.3610-3618

2018

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Synthesis of estrone selenocyanate Compounds, anti-tumor activity evaluation and Structure-activity relationship analysis

Bioorganic & medicinal chemistry, 2022-12, Vol.76, p.117086-117086, Article 117086

2022

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Discovery of ASP6918, a KRAS G12C inhibitor: Synthesis and structure-activity relationships of 1-{2,7-diazaspiro[3.5]non-2-yl}prop-2-en-1-one derivatives as covalent inhibitors with good potency and oral activity for the treatment of solid tumors

Bioorganic & medicinal chemistry, 2024-01, Vol.98, p.117581-117581, Article 117581

2024

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Structure, function and applications of carbonic anhydrase isozymes

Bioorganic & medicinal chemistry, 2013-03, Vol.21 (6), p.1570-1582

2013

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The therapeutic journey of benzimidazoles: A review

Bioorganic & medicinal chemistry, 2012-11, Vol.20 (21), p.6208-6236

2012

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Using in vitro ADME data for lead compound selection: An emphasis on PAMPA pH 5 permeability and oral bioavailability

Bioorganic & medicinal chemistry, 2022-02, Vol.56, p.116588-116588, Article 116588

2022

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Bismuth(III) complexes with 2-acetylpyridine- and 2-benzoylpyridine-derived hydrazones: Antimicrobial and cytotoxic activities and effects on the clonogenic survival of human solid tumor cells

Bioorganic & medicinal chemistry, 2016-07, Vol.24 (13), p.2988-2998

2016

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Novel thiazolo[3,2-b]-1,2,4-triazoles derived from naproxen with analgesic/anti-inflammatory properties: Synthesis, biological evaluation and molecular modeling studies

Bioorganic & medicinal chemistry, 2015-05, Vol.23 (10), p.2518-2528

2015

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The synthesis and evaluation of triazolopyrimidines as anti-tubercular agents

Bioorganic & medicinal chemistry, 2017-08, Vol.25 (15), p.3922-3946

2017

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The 3-D conformational shape of N-naphthyl-cyclopenta[d]pyrimidines affects their potency as microtubule targeting agents and their antitumor activity

Bioorganic & medicinal chemistry, 2021-01, Vol.29, p.115887-115887, Article 115887

2021

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Lead optimization of pyrido[2,3–d][1]benzazepin-6-one derivatives leading to the discovery of a potent, selective, and orally available human parathyroid hormone receptor 1 (hPTHR1) antagonist (DS69910557)

Bioorganic & medicinal chemistry, 2022-06, Vol.64, p.116763-116763, Article 116763

2022

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Discovery of new thieno[2,3-d]pyrimidine and thiazolo[5,4-d]pyrimidine derivatives as orally active phosphoinositide 3-kinase inhibitors

Bioorganic & medicinal chemistry, 2021-01, Vol.29, p.115890, Article 115890

2021

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Synthesis of novel inhibitors of β-glucuronidase based on benzothiazole skeleton and study of their binding affinity by molecular docking

Bioorganic & medicinal chemistry, 2011-07, Vol.19 (14), p.4286-4294

2011

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Morita–Baylis–Hillman adducts: Biological activities and potentialities to the discovery of new cheaper drugs

Bioorganic & medicinal chemistry, 2012-07, Vol.20 (13), p.3954-3971

2012

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Impact of the structure-activity relationship of AHL analogues on quorum sensing in Gram-negative bacteria

Bioorganic & medicinal chemistry, 2020-02, Vol.28 (3), p.115282-115282, Article 115282

Chbib, Christiane

2020

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Structure-activity relationship analyses of fusidic acid derivatives highlight crucial role of the C-21 carboxylic acid moiety to its anti-mycobacterial activity

Bioorganic & medicinal chemistry, 2020-07, Vol.28 (13), p.115530-115530, Article 115530

2020

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Thiazolidine-2,4-diones: Progress towards multifarious applications

Bioorganic & medicinal chemistry, 2013-04, Vol.21 (7), p.1599-1620

2013

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Design, synthesis and biological evaluation of new hybrid anticonvulsants derived from N-benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide and 2-(2,5-dioxopyrrolidin-1-yl)butanamide derivatives

Bioorganic & medicinal chemistry, 2015-05, Vol.23 (10), p.2548-2561

2015

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An insight into synthetic Schiff bases revealing antiproliferative activities in vitro

Synthesis, structure–activity relationships, and mechanism of action of anti-HIV-1 lamellarin α 20-sulfate analogues

Synthesis and molecular docking of 1,2,3-triazole-based sulfonamides as aromatase inhibitors

Medicinal attributes of pyrazolo[3,4-d]pyrimidines: A review

Discovery of a new class of valosine containing protein (VCP/P97) inhibitors for the treatment of colorectal cancer

Quinazolines and quinazolinones as ubiquitous structural fragments in medicinal chemistry: An update on the development of synthetic methods and pharmacological diversification

Synthesis of novel indole-thiazolidinone hybrid structures as promising scaffold with anticancer potential

Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisinin

Synthesis of estrone selenocyanate Compounds, anti-tumor activity evaluation and Structure-activity relationship analysis

Discovery of ASP6918, a KRAS G12C inhibitor: Synthesis and structure-activity relationships of 1-{2,7-diazaspiro[3.5]non-2-yl}prop-2-en-1-one derivatives as covalent inhibitors with good potency and oral activity for the treatment of solid tumors

Structure, function and applications of carbonic anhydrase isozymes

The therapeutic journey of benzimidazoles: A review

Using in vitro ADME data for lead compound selection: An emphasis on PAMPA pH 5 permeability and oral bioavailability

Bismuth(III) complexes with 2-acetylpyridine- and 2-benzoylpyridine-derived hydrazones: Antimicrobial and cytotoxic activities and effects on the clonogenic survival of human solid tumor cells

Novel thiazolo[3,2-b]-1,2,4-triazoles derived from naproxen with analgesic/anti-inflammatory properties: Synthesis, biological evaluation and molecular modeling studies

The synthesis and evaluation of triazolopyrimidines as anti-tubercular agents

The 3-D conformational shape of N-naphthyl-cyclopenta[d]pyrimidines affects their potency as microtubule targeting agents and their antitumor activity

Lead optimization of pyrido[2,3–d][1]benzazepin-6-one derivatives leading to the discovery of a potent, selective, and orally available human parathyroid hormone receptor 1 (hPTHR1) antagonist (DS69910557)

Discovery of new thieno[2,3-d]pyrimidine and thiazolo[5,4-d]pyrimidine derivatives as orally active phosphoinositide 3-kinase inhibitors

Synthesis of novel inhibitors of β-glucuronidase based on benzothiazole skeleton and study of their binding affinity by molecular docking

Morita–Baylis–Hillman adducts: Biological activities and potentialities to the discovery of new cheaper drugs

Impact of the structure-activity relationship of AHL analogues on quorum sensing in Gram-negative bacteria

Structure-activity relationship analyses of fusidic acid derivatives highlight crucial role of the C-21 carboxylic acid moiety to its anti-mycobacterial activity

Thiazolidine-2,4-diones: Progress towards multifarious applications

Design, synthesis and biological evaluation of new hybrid anticonvulsants derived from N-benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide and 2-(2,5-dioxopyrrolidin-1-yl)butanamide derivatives

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