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Unraveling the Mechanism of Protein Disaggregation Through a ClpB-DnaK Interaction

Science (American Association for the Advancement of Science), 2013-03, Vol.339 (6123), p.1080-1083

2013

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Molecular mechanism of ATP binding and ion channel activation in P2X receptors

Nature (London), 2012-05, Vol.485 (7397), p.207-212

2012

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A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy

Nature chemical biology, 2014-12, Vol.10 (12), p.1013-1019

2014

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Structural basis of RNA recognition and activation by innate immune receptor RIG-I

Nature (London), 2011-11, Vol.479 (7373), p.423-427

2011

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Structural analysis of leader peptide binding enables leader-free cyanobactin processing

Nature chemical biology, 2015-08, Vol.11 (8), p.558-563

2015

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Molecular switch-like regulation enables global subunit coordination in a viral ring ATPase

Proceedings of the National Academy of Sciences - PNAS, 2018-07, Vol.115 (31), p.7961-7966

2018

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Chaperones convert the energy from ATP into the nonequilibrium stabilization of native proteins

Nature chemical biology, 2018-04, Vol.14 (4), p.388-395

2018

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Pharmacological targeting of the pseudokinase Her3

Nature chemical biology, 2014-12, Vol.10 (12), p.1006

2014

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Asymmetric drug binding in an ATP-loaded inward-facing state of an ABC transporter

Nature chemical biology, 2022-02, Vol.18 (2), p.226-235

2022

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Rethinking glycolysis: on the biochemical logic of metabolic pathways

Nature chemical biology, 2012-05, Vol.8 (6), p.509-517

2012

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Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler

Proceedings of the National Academy of Sciences - PNAS, 2009-08, Vol.106 (33), p.13770-13774

2009

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Allosteric signal transmission in the nucleotide-binding domain of 70-kDa heat shock protein (Hsp70) molecular chaperones

Proceedings of the National Academy of Sciences - PNAS, 2011-04, Vol.108 (17), p.6987-6992

2011

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Short-range translocation by a restriction enzyme motor triggers diffusion along DNA

Nature chemical biology, 2024-06, Vol.20 (6), p.689-698

2024

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The p110 delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors

Nature chemical biology, 2010-02, Vol.6 (2), p.117-124

2010

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Mechanism of folding chamber closure in a group II chaperonin

Nature (London), 2010-01, Vol.463 (7279), p.379-383

2010

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Negative cooperativity in the nitrogenase Fe protein electron delivery cycle

Proceedings of the National Academy of Sciences - PNAS, 2016-10, Vol.113 (40), p.E5783-E5791

2016

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Nucleotide Interactions of the Human Voltage-dependent Anion Channel

The Journal of biological chemistry, 2014-05, Vol.289 (19), p.13397-13406

2014

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Dynamic Ligand-induced Conformational Rearrangements in P-glycoprotein as Probed by Fluorescence Resonance Energy Transfer Spectroscopy

The Journal of biological chemistry, 2012-01, Vol.287 (2), p.1112-1127

2012

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ATP-competitive partial antagonists of the IRE1α RNase segregate outputs of the UPR

Nature chemical biology, 2021-11, Vol.17 (11), p.1148-1156

2021

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Discovery of a new ATP-binding motif involved in peptidic azoline biosynthesis

Nature chemical biology, 2014-10, Vol.10 (10), p.823-829

2014

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Structural plasticity and catalysis regulation of a thermosensor histidine kinase

Proceedings of the National Academy of Sciences - PNAS, 2009-09, Vol.106 (38), p.16185-16190

2009

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Acetate-dependent tRNA acetylation required for decoding fidelity in protein synthesis

Nature chemical biology, 2018-11, Vol.14 (11), p.1010

2018

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ATP-dependent conformational dynamics underlie the functional asymmetry of the replicative helicase from a minimalist eukaryote

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (30), p.11999-12004

2012

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Cohesin Complex: Structure and Principles of Interaction with DNA

Biochemistry (Moscow), 2024-04, Vol.89 (4), p.585-600

2024

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Inter- and intrasubunit interactions between transmembrane helices in the open state of P2X receptor channels

Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (42), p.E4045-E4054

2013

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Unraveling the Mechanism of Protein Disaggregation Through a ClpB-DnaK Interaction

Molecular mechanism of ATP binding and ion channel activation in P2X receptors

A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy

Structural basis of RNA recognition and activation by innate immune receptor RIG-I

Structural analysis of leader peptide binding enables leader-free cyanobactin processing

Molecular switch-like regulation enables global subunit coordination in a viral ring ATPase

Chaperones convert the energy from ATP into the nonequilibrium stabilization of native proteins

Pharmacological targeting of the pseudokinase Her3

Asymmetric drug binding in an ATP-loaded inward-facing state of an ABC transporter

Rethinking glycolysis: on the biochemical logic of metabolic pathways

Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler

Allosteric signal transmission in the nucleotide-binding domain of 70-kDa heat shock protein (Hsp70) molecular chaperones

Short-range translocation by a restriction enzyme motor triggers diffusion along DNA

The p110 delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors

Mechanism of folding chamber closure in a group II chaperonin

Negative cooperativity in the nitrogenase Fe protein electron delivery cycle

Nucleotide Interactions of the Human Voltage-dependent Anion Channel

Dynamic Ligand-induced Conformational Rearrangements in P-glycoprotein as Probed by Fluorescence Resonance Energy Transfer Spectroscopy

ATP-competitive partial antagonists of the IRE1α RNase segregate outputs of the UPR

Discovery of a new ATP-binding motif involved in peptidic azoline biosynthesis

Structural plasticity and catalysis regulation of a thermosensor histidine kinase

Acetate-dependent tRNA acetylation required for decoding fidelity in protein synthesis

ATP-dependent conformational dynamics underlie the functional asymmetry of the replicative helicase from a minimalist eukaryote

Cohesin Complex: Structure and Principles of Interaction with DNA

Inter- and intrasubunit interactions between transmembrane helices in the open state of P2X receptor channels

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