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One-Step Conversion of Azine N-Oxides to α-1,2,4-Triazolo-, 1,2,3-Triazolo, Imidazolo-, and Pyrazoloheteroarenes

Journal of organic chemistry, 2010-04, Vol.75 (8), p.2722-2725

Keith, John M

2010

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Asymmetric Hydrocyanation of Hydrazones Catalyzed by Lanthanide−PYBOX Complexes

Organic letters, 2004-01, Vol.6 (2), p.153-155

2004

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Biochemical and Biological Properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a Mechanism-Based Inhibitor of Fatty Acid Amide Hydrolase

Anesthesia and analgesia, 2009-01, Vol.108 (1), p.316-329

2009

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One-Step Conversion of Azine N‑Oxides to α‑N‑Aryltriflamidoazines

Journal of organic chemistry, 2012-12, Vol.77 (24), p.11313-11318

Keith, John M

2012

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Lead identification of acetylcholinesterase inhibitors-histamine H3 receptor antagonists from molecular modeling

Bioorganic & medicinal chemistry, 2008-03, Vol.16 (6), p.2968-2973

2008

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One Step Conversion of Heteroaromatic-N-Oxides to Imidazolo-Heteroarenes

Journal of organic chemistry, 2008-01, Vol.73 (1), p.327-330

Keith, John M

2008

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Dual serotonin transporter/histamine H3 ligands : Optimization of the H3 pharmacophore

Bioorganic & medicinal chemistry letters, 2007-02, Vol.17 (3), p.702-706

2007

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A Single Amino Acid Difference between Mouse and Human 5-Lipoxygenase Activating Protein (FLAP) Explains the Speciation and Differential Pharmacology of Novel FLAP Inhibitors

The Journal of biological chemistry, 2016-06, Vol.291 (24), p.12724-12731

2016

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Exploration of the Mitsunobu Reaction with Tosyl- and Boc-Hydrazones as Nucleophilic Agents

Journal of organic chemistry, 2006-09, Vol.71 (18), p.7113-7116

2006

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Thiadiazolopiperazinyl ureas as inhibitors of fatty acid amide hydrolase

Bioorganic & medicinal chemistry, 2008-09, Vol.18 (17), p.4838-4843

2008

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Heteroarylureas with spirocyclic diamine cores as inhibitors of fatty acid amide hydrolase

Bioorganic & medicinal chemistry letters, 2014-02, Vol.24 (3), p.737-741

2014

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The SAR of brain penetration for a series of heteroaryl urea FAAH inhibitors

Bioorganic & medicinal chemistry letters, 2016-07, Vol.26 (13), p.3109-3114

2016

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1-Aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase

Bioorganic & medicinal chemistry letters, 2014-03, Vol.24 (5), p.1280-1284

2014

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Heteroaryl urea inhibitors of fatty acid amide hydrolase: Structure–mutagenicity relationships for arylamine metabolites

Bioorganic & medicinal chemistry letters, 2012-12, Vol.22 (24), p.7357-7362

2012

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Polypharmacology of Small-Molecule Modulators of the 5-Lipoxygenase Activating Protein (FLAP) Observed via a High-throughput Lipidomics Platform

Journal of biomolecular screening, 2016-02, Vol.21 (2), p.127-135

2016

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Disruption of fatty acid amide hydrolase activity prevents the effects of chronic stress on anxiety and amygdalar microstructure

Molecular psychiatry, 2013-10, Vol.18 (10), p.1125-1135

2013

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Synthesis and biological activity of piperazine and diazepane amides that are histamine H3 antagonists and serotonin reuptake inhibitors

Bioorganic & medicinal chemistry letters, 2008, Vol.18 (1), p.39-43

2008

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Pyrrolidino-tetrahydroisoquinolines bearing pendant heterocycles as potent dual H3 antagonist and serotonin transporter inhibitors

Bioorganic & medicinal chemistry letters, 2007-08, Vol.17 (15), p.4374-4377

2007

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Novel tetrahydroisoquinolines are histamine H3 antagonists and serotonin reuptake inhibitors

Bioorganic & medicinal chemistry letters, 2007-02, Vol.17 (4), p.1047-1051

2007

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Pyrrolidino-tetrahydroisoquinolines as potent dual H3 antagonist and serotonin transporter inhibitors

Bioorganic & medicinal chemistry letters, 2007-05, Vol.17 (9), p.2603-2607

2007

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Novel naphthyridines are histamine H3 antagonists and serotonin reuptake transporter inhibitors

Bioorganic & medicinal chemistry letters, 2007-05, Vol.17 (9), p.2566-2569

2007

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2-Aryloxymethylmorpholine histamine H(3) antagonists

Bioorganic & medicinal chemistry letters, 2008-11, Vol.18 (21), p.5796-5799

2008

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Pre-clinical characterization of aryloxypyridine amides as histamine H3 receptor antagonists: Identification of candidates for clinical development

Bioorganic & medicinal chemistry letters, 2010-07, Vol.20 (14), p.4210-4214

2010

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Dual serotonin transporter inhibitor/histamine H3 antagonists : Development of rigidified H3 pharmacophores

Bioorganic & medicinal chemistry letters, 2007-10, Vol.17 (19), p.5325-5329

2007

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Outbreak of Necrotizing Enterocolitis Caused by Norovirus in a Neonatal Intensive Care Unit

The Journal of pediatrics, 2008-09, Vol.153 (3), p.339-344

2008

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One-Step Conversion of Azine N-Oxides to α-1,2,4-Triazolo-, 1,2,3-Triazolo, Imidazolo-, and Pyrazoloheteroarenes

Asymmetric Hydrocyanation of Hydrazones Catalyzed by Lanthanide−PYBOX Complexes

Biochemical and Biological Properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a Mechanism-Based Inhibitor of Fatty Acid Amide Hydrolase

One-Step Conversion of Azine N‑Oxides to α‑N‑Aryltriflamidoazines

Lead identification of acetylcholinesterase inhibitors-histamine H3 receptor antagonists from molecular modeling

One Step Conversion of Heteroaromatic-N-Oxides to Imidazolo-Heteroarenes

Dual serotonin transporter/histamine H3 ligands : Optimization of the H3 pharmacophore

A Single Amino Acid Difference between Mouse and Human 5-Lipoxygenase Activating Protein (FLAP) Explains the Speciation and Differential Pharmacology of Novel FLAP Inhibitors

Exploration of the Mitsunobu Reaction with Tosyl- and Boc-Hydrazones as Nucleophilic Agents

Thiadiazolopiperazinyl ureas as inhibitors of fatty acid amide hydrolase

Heteroarylureas with spirocyclic diamine cores as inhibitors of fatty acid amide hydrolase

The SAR of brain penetration for a series of heteroaryl urea FAAH inhibitors

1-Aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase

Heteroaryl urea inhibitors of fatty acid amide hydrolase: Structure–mutagenicity relationships for arylamine metabolites

Polypharmacology of Small-Molecule Modulators of the 5-Lipoxygenase Activating Protein (FLAP) Observed via a High-throughput Lipidomics Platform

Disruption of fatty acid amide hydrolase activity prevents the effects of chronic stress on anxiety and amygdalar microstructure

Synthesis and biological activity of piperazine and diazepane amides that are histamine H3 antagonists and serotonin reuptake inhibitors

Pyrrolidino-tetrahydroisoquinolines bearing pendant heterocycles as potent dual H3 antagonist and serotonin transporter inhibitors

Novel tetrahydroisoquinolines are histamine H3 antagonists and serotonin reuptake inhibitors

Pyrrolidino-tetrahydroisoquinolines as potent dual H3 antagonist and serotonin transporter inhibitors

Novel naphthyridines are histamine H3 antagonists and serotonin reuptake transporter inhibitors

2-Aryloxymethylmorpholine histamine H(3) antagonists

Pre-clinical characterization of aryloxypyridine amides as histamine H3 receptor antagonists: Identification of candidates for clinical development

Dual serotonin transporter inhibitor/histamine H3 antagonists : Development of rigidified H3 pharmacophores

Outbreak of Necrotizing Enterocolitis Caused by Norovirus in a Neonatal Intensive Care Unit

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