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The Gemin associates of survival motor neuron are required for motor function in Drosophila

PloS one, 2013-12, Vol.8 (12), p.e83878-e83878

2013

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Extract from the Marine Seaweed Padina pavonica Protects Mitochondrial Biomembranes from Damage by Amyloidogenic Peptides

Molecules (Basel, Switzerland), 2021-03, Vol.26 (5), p.1444

2021

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Genetic analysis of ALS cases in the isolated island population of Malta

European journal of human genetics : EJHG, 2021-04, Vol.29 (4), p.604-614

2021

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Genetic screen identifies a requirement for SMN in mRNA localisation within the Drosophila oocyte

BMC research notes, 2018-06, Vol.11 (1), p.378-378, Article 378

2018

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Genetic Interactions between the Members of the SMN-Gemins Complex in Drosophila

PloS one, 2015-06, Vol.10 (6), p.e0130974

2015

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Novel interactors of the Drosophila Survival Motor Neuron (SMN) Complex suggest its full conservation

FEBS letters, 2017-11, Vol.591 (21), p.3600-3614

2017

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Disruption of snRNP biogenesis factors Tgs1 and pICln induces phenotypes that mirror aspects of SMN-Gemins complex perturbation in Drosophila , providing new insights into spinal muscular atrophy

Neurobiology of disease, 2016-10, Vol.94, p.245-258

2016

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SMN and Gemins: ‘We are family' … or are we?: Insights into the partnership between Gemins and the spinal muscular atrophy disease protein SMN

BioEssays, 2010-12, Vol.32 (12), p.1077-1089

Cauchi, Ruben J

2010

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Loss of amyotrophic lateral sclerosis risk factor SCFD1 causes motor dysfunction in Drosophila

Neurobiology of aging, 2023-06, Vol.126, p.67-76

2023

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Modelling motor neuron disease in fruit flies: Lessons from spinal muscular atrophy

Journal of neuroscience methods, 2018-12, Vol.310, p.3-11

2018

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A motor function for the DEAD-box RNA helicase, Gemin3, in Drosophila

PLoS genetics, 2008-11, Vol.4 (11), p.e1000265-e1000265

2008

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Tau-induced mitochondrial membrane perturbation is dependent upon cardiolipin

Biochimica et biophysica acta. Biomembranes, 2020-02, Vol.1862 (2), p.183064, Article 183064

2020

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Conserved requirement for DEAD-box RNA helicase Gemin3 in Drosophila oogenesis

BMC research notes, 2012-02, Vol.5 (1), p.120-120, Article 120

Cauchi, Ruben J

2012

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SOD1 D91A variant in the southernmost tip of Europe: a heterozygous ALS patient resident on the island of Gozo

European journal of human genetics : EJHG, 2022-07, Vol.30 (7), p.856-859

2022

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Gem Depletion: Amyotrophic Lateral Sclerosis and Spinal Muscular Atrophy Crossover

CNS neuroscience & therapeutics, 2014-07, Vol.20 (7), p.574-581

Cauchi, Ruben J.

2014

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SMN complex member Gemin3 self-interacts and has a functional relationship with ALS-linked proteins TDP-43, FUS and Sod1

Scientific reports, 2019-12, Vol.9 (1), p.18666-19, Article 18666

2019

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Genetic landscape of ALS in Malta based on a quinquennial analysis

Neurobiology of aging, 2023-03, Vol.123, p.200-207

2023

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Toxic oligomers of the amyloidogenic HypF-N protein form pores in mitochondrial membranes

Scientific reports, 2020-10, Vol.10 (1), p.17733, Article 17733

2020

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An activator of voltage-gated K + channels Kv1.1 as a therapeutic candidate for episodic ataxia type 1

Proceedings of the National Academy of Sciences - PNAS, 2023-08, Vol.120 (31), p.e2207978120-e2207978120

2023

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Extracts from two ubiquitous Mediterranean plants ameliorate cellular and animal models of neurodegenerative proteinopathies

Neuroscience letters, 2017-01, Vol.638, p.12-20

2017

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Gem formation upon constitutive Gemin3 overexpression in Drosophila

Cell biology international, 2011-12, Vol.35 (12), p.1233-1238

Cauchi, Ruben J.

2011

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Drosophila SMN complex proteins Gemin2, Gemin3, and Gemin5 are components of U bodies

Experimental cell research, 2010-08, Vol.316 (14), p.2354-2364

2010

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A molecular view of amyotrophic lateral sclerosis through the lens of interaction network modules

PloS one, 2022-05, Vol.17 (5), p.e0268159-e0268159

2022

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The Fly as a Model for Neurodegenerative Diseases: Is It Worth the Jump?

Neuro-degenerative diseases, 2006-01, Vol.3 (6), p.338-356

2006

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Genome-wide expression analysis of a spinal muscular atrophy model: towards discovery of new drug targets

PloS one, 2008-01, Vol.3 (1), p.e1404-e1404

2008

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The Gemin associates of survival motor neuron are required for motor function in Drosophila

Extract from the Marine Seaweed Padina pavonica Protects Mitochondrial Biomembranes from Damage by Amyloidogenic Peptides

Genetic analysis of ALS cases in the isolated island population of Malta

Genetic screen identifies a requirement for SMN in mRNA localisation within the Drosophila oocyte

Genetic Interactions between the Members of the SMN-Gemins Complex in Drosophila

Novel interactors of the Drosophila Survival Motor Neuron (SMN) Complex suggest its full conservation

Disruption of snRNP biogenesis factors Tgs1 and pICln induces phenotypes that mirror aspects of SMN-Gemins complex perturbation in Drosophila , providing new insights into spinal muscular atrophy

SMN and Gemins: ‘We are family' … or are we?: Insights into the partnership between Gemins and the spinal muscular atrophy disease protein SMN

Loss of amyotrophic lateral sclerosis risk factor SCFD1 causes motor dysfunction in Drosophila

Modelling motor neuron disease in fruit flies: Lessons from spinal muscular atrophy

A motor function for the DEAD-box RNA helicase, Gemin3, in Drosophila

Tau-induced mitochondrial membrane perturbation is dependent upon cardiolipin

Conserved requirement for DEAD-box RNA helicase Gemin3 in Drosophila oogenesis

SOD1 D91A variant in the southernmost tip of Europe: a heterozygous ALS patient resident on the island of Gozo

Gem Depletion: Amyotrophic Lateral Sclerosis and Spinal Muscular Atrophy Crossover

SMN complex member Gemin3 self-interacts and has a functional relationship with ALS-linked proteins TDP-43, FUS and Sod1

Genetic landscape of ALS in Malta based on a quinquennial analysis

Toxic oligomers of the amyloidogenic HypF-N protein form pores in mitochondrial membranes

An activator of voltage-gated K + channels Kv1.1 as a therapeutic candidate for episodic ataxia type 1

Extracts from two ubiquitous Mediterranean plants ameliorate cellular and animal models of neurodegenerative proteinopathies

Gem formation upon constitutive Gemin3 overexpression in Drosophila

Drosophila SMN complex proteins Gemin2, Gemin3, and Gemin5 are components of U bodies

A molecular view of amyotrophic lateral sclerosis through the lens of interaction network modules

The Fly as a Model for Neurodegenerative Diseases: Is It Worth the Jump?

Genome-wide expression analysis of a spinal muscular atrophy model: towards discovery of new drug targets

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