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Protein function prediction using domain families

BMC bioinformatics, 2013-02, Vol.14 Suppl 3 (Suppl 3), p.S5-S5, Article S5

2013

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Biological impact of mutually exclusive exon switching

PLoS computational biology, 2021-03, Vol.17 (3), p.e1008708-e1008708

2021

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Generating functional protein variants with variational autoencoders

PLoS computational biology, 2021-02, Vol.17 (2), p.e1008736-e1008736

2021

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Protein function prediction – the power of multiplicity

Trends in biotechnology (Regular ed.), 2009-04, Vol.27 (4), p.210-219

2009

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Predicting human and viral protein variants affecting COVID-19 susceptibility and repurposing therapeutics

Scientific reports, 2024-06, Vol.14 (1), p.14208-19, Article 14208

2024

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An analysis of tissue-specific alternative splicing at the protein level

PLoS computational biology, 2020-10, Vol.16 (10), p.e1008287-e1008287

2020

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Low-Density Lipoprotein Receptor Gene Familial Hypercholesterolemia Variant Database: Update and Pathological Assessment

Annals of human genetics, 2012-09, Vol.76 (5), p.387-401

2012

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Analysis of temporal transcription expression profiles reveal links between protein function and developmental stages of Drosophila melanogaster

PLoS computational biology, 2017-10, Vol.13 (10), p.e1005791-e1005791

2017

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Exploring the evolution of novel enzyme functions within structurally defined protein superfamilies

PLoS computational biology, 2012-03, Vol.8 (3), p.e1002403-e1002403

2012

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Alpha Helices Are More Robust to Mutations than Beta Strands

PLoS computational biology, 2016-12, Vol.12 (12), p.e1005242-e1005242

2016

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Inferring function using patterns of native disorder in proteins

PLoS computational biology, 2007-08, Vol.3 (8), p.e162-e162

2007

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An Ancient Fingerprint Indicates the Common Ancestry of Rossmann-Fold Enzymes Utilizing Different Ribose-Based Cofactors

PLoS biology, 2016-03, Vol.14 (3), p.e1002396-e1002396

2016

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Genome-wide RNA-Sequencing analysis identifies a distinct fibrosis gene signature in the conjunctiva after glaucoma surgery

Scientific reports, 2017-07, Vol.7 (1), p.5644-13, Article 5644

2017

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Diversity and distribution of nuclease bacteriocins in bacterial genomes revealed using Hidden Markov Models

PLoS computational biology, 2017-07, Vol.13 (7), p.e1005652-e1005652

2017

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Biases in the experimental annotations of protein function and their effect on our understanding of protein function space

PLoS computational biology, 2013-05, Vol.9 (5), p.e1003063-e1003063

2013

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KinFams: De-Novo Classification of Protein Kinases Using CATH Functional Units

Biomolecules (Basel, Switzerland), 2023-02, Vol.13 (2), p.277

2023

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The complexity of protein interactions unravelled from structural disorder

PLoS computational biology, 2021-01, Vol.17 (1), p.e1008546-e1008546

2021

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Systematic Mapping of Protein Mutational Space by Prolonged Drift Reveals the Deleterious Effects of Seemingly Neutral Mutations

PLoS computational biology, 2015-08, Vol.11 (8), p.e1004421

2015

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Conformational diversity analysis reveals three functional mechanisms in proteins

PLoS computational biology, 2017-02, Vol.13 (2), p.e1005398

2017

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Determining effects of non-synonymous SNPs on protein-protein interactions using supervised and semi-supervised learning

PLoS computational biology, 2014-05, Vol.10 (5), p.e1003592

2014

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Quantitative profiling of protease specificity

PLoS computational biology, 2021-02, Vol.17 (2), p.e1008101-e1008101

2021

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Global patterns of protein domain gain and loss in superkingdoms

PLoS computational biology, 2014-01, Vol.10 (1), p.e1003452-e1003452

2014

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Exploring the composition of protein-ligand binding sites on a large scale

PLoS computational biology, 2013-11, Vol.9 (11), p.e1003321

2013

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FLORA: a novel method to predict protein function from structure in diverse superfamilies

PLoS computational biology, 2009-08, Vol.5 (8), p.e1000485

2009

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CATHEDRAL: a fast and effective algorithm to predict folds and domain boundaries from multidomain protein structures

PLoS computational biology, 2007-11, Vol.3 (11), p.e232-e232

2007

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Protein function prediction using domain families

Biological impact of mutually exclusive exon switching

Generating functional protein variants with variational autoencoders

Protein function prediction – the power of multiplicity

Predicting human and viral protein variants affecting COVID-19 susceptibility and repurposing therapeutics

An analysis of tissue-specific alternative splicing at the protein level

Low-Density Lipoprotein Receptor Gene Familial Hypercholesterolemia Variant Database: Update and Pathological Assessment

Analysis of temporal transcription expression profiles reveal links between protein function and developmental stages of Drosophila melanogaster

Exploring the evolution of novel enzyme functions within structurally defined protein superfamilies

Alpha Helices Are More Robust to Mutations than Beta Strands

Inferring function using patterns of native disorder in proteins

An Ancient Fingerprint Indicates the Common Ancestry of Rossmann-Fold Enzymes Utilizing Different Ribose-Based Cofactors

Genome-wide RNA-Sequencing analysis identifies a distinct fibrosis gene signature in the conjunctiva after glaucoma surgery

Diversity and distribution of nuclease bacteriocins in bacterial genomes revealed using Hidden Markov Models

Biases in the experimental annotations of protein function and their effect on our understanding of protein function space

KinFams: De-Novo Classification of Protein Kinases Using CATH Functional Units

The complexity of protein interactions unravelled from structural disorder

Systematic Mapping of Protein Mutational Space by Prolonged Drift Reveals the Deleterious Effects of Seemingly Neutral Mutations

Conformational diversity analysis reveals three functional mechanisms in proteins

Determining effects of non-synonymous SNPs on protein-protein interactions using supervised and semi-supervised learning

Quantitative profiling of protease specificity

Global patterns of protein domain gain and loss in superkingdoms

Exploring the composition of protein-ligand binding sites on a large scale

FLORA: a novel method to predict protein function from structure in diverse superfamilies

CATHEDRAL: a fast and effective algorithm to predict folds and domain boundaries from multidomain protein structures

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