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Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance

PLoS genetics, 2009-10, Vol.5 (10), p.e1000705

2009

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Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin

PLoS pathogens, 2009-07, Vol.5 (7), p.e1000532-e1000532

2009

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PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90

PLoS pathogens, 2010-08, Vol.6 (8), p.e1001069-e1001069

2010

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Hsp90 orchestrates stress response signaling governing fungal drug resistance

PLoS pathogens, 2009-08, Vol.5 (8), p.e1000471-e1000471

2009

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Hsp90 governs dispersion and drug resistance of fungal biofilms

PLoS pathogens, 2011-09, Vol.7 (9), p.e1002257-e1002257

2011

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Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata

PLoS pathogens, 2012-05, Vol.8 (5), p.e1002718-e1002718

2012

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Functional connections between cell cycle and proteostasis in the regulation of Candida albicans morphogenesis

Cell reports (Cambridge), 2021-02, Vol.34 (8), p.108781-108781, Article 108781

2021

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Mapping the Hsp90 genetic interaction network in Candida albicans reveals environmental contingency and rewired circuitry

PLoS genetics, 2012-03, Vol.8 (3), p.e1002562

2012

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Lysine Deacetylases Hda1 and Rpd3 Regulate Hsp90 Function thereby Governing Fungal Drug Resistance

Cell reports (Cambridge), 2012-10, Vol.2 (4), p.878-888

2012

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Fitness Trade-Offs Associated with the Evolution of Resistance to Antifungal Drug Combinations

Cell reports (Cambridge), 2015-02, Vol.10 (5), p.809-819

2015

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Genetic and genomic architecture of the evolution of resistance to antifungal drug combinations

PLoS genetics, 2013-04, Vol.9 (4), p.e1003390-e1003390

2013

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Global proteomic analyses define an environmentally contingent Hsp90 interactome and reveal chaperone-dependent regulation of stress granule proteins and the R2TP complex in a fungal pathogen

PLoS biology, 2019-07, Vol.17 (7), p.e3000358-e3000358

2019

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Functional Genomic Analysis of Candida albicans Adherence Reveals a Key Role for the Arp2/3 Complex in Cell Wall Remodelling and Biofilm Formation

PLoS genetics, 2016-11, Vol.12 (11), p.e1006452-e1006452

2016

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Hsp90 orchestrates transcriptional regulation by Hsf1 and cell wall remodelling by MAPK signalling during thermal adaptation in a pathogenic yeast

PLoS pathogens, 2012-12, Vol.8 (12), p.e1003069-e1003069

2012

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A functionally divergent intrinsically disordered region underlying the conservation of stochastic signaling

PLoS genetics, 2021-09, Vol.17 (9), p.e1009629-e1009629

2021

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Environment-induced same-sex mating in the yeast Candida albicans through the Hsf1-Hsp90 pathway

PLoS biology, 2019-03, Vol.17 (3), p.e2006966-e2006966

2019

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Global Analysis of the Fungal Microbiome in Cystic Fibrosis Patients Reveals Loss of Function of the Transcriptional Repressor Nrg1 as a Mechanism of Pathogen Adaptation

PLoS pathogens, 2015-11, Vol.11 (11), p.e1005308-e1005308

2015

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Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs

PLoS genetics, 2018-04, Vol.14 (4), p.e1007319

2018

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Signaling through Lrg1, Rho1 and Pkc1 Governs Candida albicans Morphogenesis in Response to Diverse Cues

PLoS genetics, 2016-10, Vol.12 (10), p.e1006405-e1006405

2016

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Mapping the Hsp90 Genetic Network Reveals Ergosterol Biosynthesis and Phosphatidylinositol-4-Kinase Signaling as Core Circuitry Governing Cellular Stress

PLoS genetics, 2016-06, Vol.12 (6), p.e1006142-e1006142

2016

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Metal Chelation as a Powerful Strategy to Probe Cellular Circuitry Governing Fungal Drug Resistance and Morphogenesis

PLoS genetics, 2016-10, Vol.12 (10), p.e1006350

2016

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Functional genomic analysis of genes important for Candida albicans fitness in diverse environmental conditions

Cell reports (Cambridge), 2024-08, Vol.43 (8), p.114601, Article 114601

2024

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Functional Divergence of Hsp90 Genetic Interactions in Biofilm and Planktonic Cellular States

PloS one, 2015-09, Vol.10 (9), p.e0137947

2015

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Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space

PLoS genetics, 2018-03, Vol.14 (3), p.e1007270

2018

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The Hsp90 co-chaperone Sgt1 governs Candida albicans morphogenesis and drug resistance

PloS one, 2012-09, Vol.7 (9), p.e44734-e44734

2012

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Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance

Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin

PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90

Hsp90 orchestrates stress response signaling governing fungal drug resistance

Hsp90 governs dispersion and drug resistance of fungal biofilms

Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata

Functional connections between cell cycle and proteostasis in the regulation of Candida albicans morphogenesis

Mapping the Hsp90 genetic interaction network in Candida albicans reveals environmental contingency and rewired circuitry

Lysine Deacetylases Hda1 and Rpd3 Regulate Hsp90 Function thereby Governing Fungal Drug Resistance

Fitness Trade-Offs Associated with the Evolution of Resistance to Antifungal Drug Combinations

Genetic and genomic architecture of the evolution of resistance to antifungal drug combinations

Global proteomic analyses define an environmentally contingent Hsp90 interactome and reveal chaperone-dependent regulation of stress granule proteins and the R2TP complex in a fungal pathogen

Functional Genomic Analysis of Candida albicans Adherence Reveals a Key Role for the Arp2/3 Complex in Cell Wall Remodelling and Biofilm Formation

Hsp90 orchestrates transcriptional regulation by Hsf1 and cell wall remodelling by MAPK signalling during thermal adaptation in a pathogenic yeast

A functionally divergent intrinsically disordered region underlying the conservation of stochastic signaling

Environment-induced same-sex mating in the yeast Candida albicans through the Hsf1-Hsp90 pathway

Global Analysis of the Fungal Microbiome in Cystic Fibrosis Patients Reveals Loss of Function of the Transcriptional Repressor Nrg1 as a Mechanism of Pathogen Adaptation

Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs

Signaling through Lrg1, Rho1 and Pkc1 Governs Candida albicans Morphogenesis in Response to Diverse Cues

Mapping the Hsp90 Genetic Network Reveals Ergosterol Biosynthesis and Phosphatidylinositol-4-Kinase Signaling as Core Circuitry Governing Cellular Stress

Metal Chelation as a Powerful Strategy to Probe Cellular Circuitry Governing Fungal Drug Resistance and Morphogenesis

Functional genomic analysis of genes important for Candida albicans fitness in diverse environmental conditions

Functional Divergence of Hsp90 Genetic Interactions in Biofilm and Planktonic Cellular States

Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space

The Hsp90 co-chaperone Sgt1 governs Candida albicans morphogenesis and drug resistance

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