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Antifolates in cancer therapy: Structure, activity and mechanisms of drug resistance

Drug resistance updates, 2012-08, Vol.15 (4), p.183-210

2012

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The folate receptor as a rational therapeutic target for personalized cancer treatment

Drug resistance updates, 2014-10, Vol.17 (4), p.89-95

2014

Volltextzugriff (PDF)

Modulating ROS to overcome multidrug resistance in cancer

Drug resistance updates, 2018-11, Vol.41, p.1-25

2018

Volltextzugriff (PDF)

Microenvironment acidity as a major determinant of tumor chemoresistance: Proton pump inhibitors (PPIs) as a novel therapeutic approach

Drug resistance updates, 2015-11, Vol.23, p.69-78

2015

Volltextzugriff (PDF)

Lysosomotropic drugs activate TFEB via lysosomal membrane fluidization and consequent inhibition of mTORC1 activity

Cell death & disease, 2018-12, Vol.9 (12), p.1191-15, Article 1191

2018

Volltextzugriff (PDF)

Molecular basis of resistance to proteasome inhibitors in hematological malignancies

Drug resistance updates, 2015-01, Vol.18, p.18-35

2015

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Beta-casein nanovehicles for oral delivery of chemotherapeutic drugs

Nanomedicine, 2010-02, Vol.6 (1), p.119-126

2010

Volltextzugriff (PDF)

A transcriptomic examination of encased rotifer embryos reveals the developmental trajectory leading to long-term dormancy; are they "animal seeds"?

BMC genomics, 2024-01, Vol.25 (1), p.119-119, Article 119

2024

Volltextzugriff (PDF)

Rationally designed nanovehicles to overcome cancer chemoresistance

Advanced drug delivery reviews, 2013-11, Vol.65 (13-14), p.1716-1730

2013

Volltextzugriff (PDF)

Redundant angiogenic signaling and tumor drug resistance

Drug resistance updates, 2018-01, Vol.36, p.47-76

2018

Volltextzugriff (PDF)

Folylpoly-γ-glutamate synthetase: A key determinant of folate homeostasis and antifolate resistance in cancer

Drug resistance updates, 2016-09, Vol.28, p.43-64

2016

Volltextzugriff (PDF)

The role of multidrug resistance efflux transporters in antifolate resistance and folate homeostasis

Drug resistance updates, 2006-08, Vol.9 (4), p.227-246

Assaraf, Yehuda G.

2006

Volltextzugriff (PDF)

Current status of antivirals and druggable targets of SARS CoV-2 and other human pathogenic coronaviruses

Drug resistance updates, 2020-12, Vol.53, p.100721-100721, Article 100721

2020

Volltextzugriff (PDF)

The role of endolysosomal trafficking in anticancer drug resistance

Drug resistance updates, 2021-07, Vol.57, p.100769-100769, Article 100769

2021

Volltextzugriff (PDF)

Repositioning of drugs for intervention in tumor progression and metastasis: Old drugs for new targets

Drug resistance updates, 2016-05, Vol.26, p.10-27

2016

Volltextzugriff (PDF)

Could drugs inhibiting the mevalonate pathway also target cancer stem cells?

Drug resistance updates, 2016-03, Vol.25, p.13-25

2016

Volltextzugriff (PDF)

Metabolomics reveals novel insight on dormancy of aquatic invertebrate encysted embryos

Scientific reports, 2019-06, Vol.9 (1), p.8878-14, Article 8878

2019

Volltextzugriff (PDF)

Membrane fluidization by ether, other anesthetics, and certain agents abolishes P‐glycoprotein ATPase activity and modulates efflux from multidrug‐resistant cells

European journal of biochemistry, 1999-01, Vol.259 (1‐2), p.18-24

1999

Volltextzugriff (PDF)

Inhibitory effects of prostaglandin A1 on membrane transport of folates mediated by both the reduced folate carrier and ATP-driven exporters

Biochemical pharmacology, 1999-10, Vol.58 (8), p.1321-1327

1999

Volltextzugriff (PDF)

Disruption of transport activity in a D93H mutant thiamine transporter 1, from a Rogers Syndrome family

European journal of biochemistry, 2003-11, Vol.270 (22), p.4469-4477

2003

Volltextzugriff (PDF)

Efficiency of P‐glycoprotein–Mediated Exclusion of Rhodamine Dyes from Multidrug‐Resistant Cells is Determined by their Passive Transmembrane Movement Rate

European journal of biochemistry, 1997-08, Vol.248 (1), p.104-112

1997

Volltextzugriff (PDF)

Characterization by flow cytometry and fluorescein-methotrexate labeling of hydrophilic and lipophilic antifolate resistance in cultured mammalian cells

Anti-cancer drugs, 1993-10, Vol.4 (5), p.535-544

Assaraf, Yehuda G

1993

Volltextzugriff (PDF)

Determination of Multidrug Resistance Levels in Cultured Mammalian Cells Using Ornithine Decarboxylase Activity

Analytical biochemistry, 1994-01, Vol.216 (1), p.97-109

1994

Volltextzugriff (PDF)

Characterization of a human alternatively spliced truncated reduced folate carrier increasing folate accumulation in parental leukemia cells

European journal of biochemistry, 2000-02, Vol.267 (3), p.690-702

2000

Volltextzugriff (PDF)

The reduced folate carrier (RFC-1) gene is expressed in the murine epidermis

Archives of Dermatological Research, 1998-07, Vol.290 (7), p.394-396

1998

Volltextzugriff (PDF)

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Antifolates in cancer therapy: Structure, activity and mechanisms of drug resistance

The folate receptor as a rational therapeutic target for personalized cancer treatment

Modulating ROS to overcome multidrug resistance in cancer

Microenvironment acidity as a major determinant of tumor chemoresistance: Proton pump inhibitors (PPIs) as a novel therapeutic approach

Lysosomotropic drugs activate TFEB via lysosomal membrane fluidization and consequent inhibition of mTORC1 activity

Molecular basis of resistance to proteasome inhibitors in hematological malignancies

Beta-casein nanovehicles for oral delivery of chemotherapeutic drugs

A transcriptomic examination of encased rotifer embryos reveals the developmental trajectory leading to long-term dormancy; are they "animal seeds"?

Rationally designed nanovehicles to overcome cancer chemoresistance

Redundant angiogenic signaling and tumor drug resistance

Folylpoly-γ-glutamate synthetase: A key determinant of folate homeostasis and antifolate resistance in cancer

The role of multidrug resistance efflux transporters in antifolate resistance and folate homeostasis

Current status of antivirals and druggable targets of SARS CoV-2 and other human pathogenic coronaviruses

The role of endolysosomal trafficking in anticancer drug resistance

Repositioning of drugs for intervention in tumor progression and metastasis: Old drugs for new targets

Could drugs inhibiting the mevalonate pathway also target cancer stem cells?

Metabolomics reveals novel insight on dormancy of aquatic invertebrate encysted embryos

Membrane fluidization by ether, other anesthetics, and certain agents abolishes P‐glycoprotein ATPase activity and modulates efflux from multidrug‐resistant cells

Inhibitory effects of prostaglandin A1 on membrane transport of folates mediated by both the reduced folate carrier and ATP-driven exporters

Disruption of transport activity in a D93H mutant thiamine transporter 1, from a Rogers Syndrome family

Efficiency of P‐glycoprotein–Mediated Exclusion of Rhodamine Dyes from Multidrug‐Resistant Cells is Determined by their Passive Transmembrane Movement Rate

Characterization by flow cytometry and fluorescein-methotrexate labeling of hydrophilic and lipophilic antifolate resistance in cultured mammalian cells

Determination of Multidrug Resistance Levels in Cultured Mammalian Cells Using Ornithine Decarboxylase Activity

Characterization of a human alternatively spliced truncated reduced folate carrier increasing folate accumulation in parental leukemia cells

The reduced folate carrier (RFC-1) gene is expressed in the murine epidermis

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