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Cyclo‐oxygenase‐2: pharmacology, physiology, biochemistry and relevance to NSAID therapy

British journal of pharmacology, 1999-11, Vol.128 (6), p.1121-1132

1999

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Sputum and plasma endothelin-1 levels in exacerbations of chronic obstructive pulmonary disease

Thorax, 2001-01, Vol.56 (1), p.30-35

2001

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Nucleotide oligomerization domain 1 is a dominant pathway for NOS2 induction in vascular smooth muscle cells: comparison with Toll‐like receptor 4 responses in macrophages

British journal of pharmacology, 2010-08, Vol.160 (8), p.1997-2007

2010

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An Open-Label Trial of Evidence-Based Cognitive Behavior Therapy for Nightmares and Insomnia in Crime Victims With PTSD

The American journal of psychiatry, 2001-12, Vol.158 (12), p.2043-2047

2001

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In the presence of strong P2Y12 receptor blockade, aspirin provides little additional inhibition of platelet aggregation

Journal of thrombosis and haemostasis, 2011-03, Vol.9 (3), p.552-561

2011

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Purification and Characterization of Particulate Endothelium-Derived Relaxing Factor Synthase from Cultured and Native Bovine Aortic Endothelial Cells

Proceedings of the National Academy of Sciences - PNAS, 1991-12, Vol.88 (23), p.10480-10484

1991

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Pressor Effects of Circulating Endothelin are Limited by its Removal in the Pulmonary Circulation and by the Release of Prostacyclin and Endothelium-Derived Relaxing Factor

Proceedings of the National Academy of Sciences - PNAS, 1988-12, Vol.85 (24), p.9797-9800

1988

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Ex vivo assay to determine the cyclooxygenase selectivity of non‐steroidal anti‐inflammatory drugs

British journal of pharmacology, 1999-04, Vol.126 (8), p.1824-1830

1999

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Effects of non‐steroidal anti‐inflammatory drugs on cyclo‐oxygenase and lipoxygenase activity in whole blood from aspirin‐sensitive asthmatics vs healthy donors

British journal of pharmacology, 2002-12, Vol.137 (7), p.1031-1038

2002

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Selective COX‐2 inhibitors and human inflammatory bowel disease

Alimentary pharmacology & therapeutics, 1999-08, Vol.13 (8), p.1115-1117

1999

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Reduction of platelet thromboxane A2 production ex vivo and in vivo by clopidogrel therapy

Journal of thrombosis and haemostasis, 2010-03, Vol.8 (3), p.613-615

2010

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Regulation and subcellular location of nitrogen oxide synthases in RAW264.7 macrophages

Molecular pharmacology, 1992-04, Vol.41 (4), p.615-624

1992

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Perspectives of Patients With Schizophrenia and Psychiatrists Regarding Ethically Important Aspects of Research Participation

The American journal of psychiatry, 2000-01, Vol.157 (1), p.67-74

2000

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Endogenously Released Endothelin-1 from Human Pulmonary Artery Smooth Muscle Promotes Cellular Proliferation . Relevance to Pathogenesis of Pulmonary Hypertension and Vascular Remodeling

American journal of respiratory cell and molecular biology, 2001-07, Vol.25 (1), p.104-110

2001

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A771726, the active metabolite of leflunomide, directly inhibits the activity of cyclo‐oxygenase‐2 in vitro and in vivo in a substrate‐sensitive manner

British journal of pharmacology, 1999-08, Vol.127 (7), p.1589-1596

1999

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Insulin Secretion from Pancreatic B Cells Caused by L-Arginine-Derived Nitrogen Oxides

Science (American Association for the Advancement of Science), 1992-02, Vol.255 (5045), p.721-723

1992

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Use of the endothelin antagonists BQ‐123 and PD 142893 to reveal three endothelin receptors mediating smooth muscle contraction and the release of EDRF

British journal of pharmacology, 1993-10, Vol.110 (2), p.777-782

1993

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Nonsteroid Drug Selectivities for Cyclo-Oxygenase-1 Rather than Cyclo-Oxygenase-2 Are Associated with Human Gastrointestinal Toxicity: A Full in vitro Analysis

Proceedings of the National Academy of Sciences - PNAS, 1999-06, Vol.96 (13), p.7563-7568

1999

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Receptor-Mediated Release of Endothelium-Derived Relaxing Factor and Prostacyclin from Bovine Aortic Endothelial Cells is Coupled

Proceedings of the National Academy of Sciences - PNAS, 1988-04, Vol.85 (7), p.2334-2338

1988

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Placentally derived prostaglandin E2 acts via the EP4 receptor to inhibit IL‐2‐dependent proliferation of CTLL‐2 T cells

Clinical and experimental immunology, 2002-02, Vol.127 (2), p.263-269

2002

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Expression and Activation of the Farnesoid X Receptor in the Vasculature

Proceedings of the National Academy of Sciences - PNAS, 2004-03, Vol.101 (10), p.3668-3673

2004

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Aspirin and the in vitro linear relationship between thromboxane A2‐mediated platelet aggregation and platelet production of thromboxane A2

Journal of thrombosis and haemostasis, 2008-11, Vol.6 (11), p.1933-1943

2008

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Mediation via different receptors of the vasoconstrictor effects of endothelins and sarafotoxins in the systemic circulation and renal vasculature of the anaesthetized rat

British journal of pharmacology, 1993-03, Vol.108 (3), p.776-779

1993

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Aspirin has little additional anti‐platelet effect in healthy volunteers receiving prasugrel

Journal of thrombosis and haemostasis, 2011-10, Vol.9 (10), p.2050-2056

2011

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Imagery rehearsal therapy for chronic nightmares in sexual assault survivors with posttraumatic stress disorder: a randomized controlled trial

JAMA : the journal of the American Medical Association, 2001-08, Vol.286 (5), p.537

2001

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Cyclo‐oxygenase‐2: pharmacology, physiology, biochemistry and relevance to NSAID therapy

Sputum and plasma endothelin-1 levels in exacerbations of chronic obstructive pulmonary disease

Nucleotide oligomerization domain 1 is a dominant pathway for NOS2 induction in vascular smooth muscle cells: comparison with Toll‐like receptor 4 responses in macrophages

An Open-Label Trial of Evidence-Based Cognitive Behavior Therapy for Nightmares and Insomnia in Crime Victims With PTSD

In the presence of strong P2Y12 receptor blockade, aspirin provides little additional inhibition of platelet aggregation

Purification and Characterization of Particulate Endothelium-Derived Relaxing Factor Synthase from Cultured and Native Bovine Aortic Endothelial Cells

Pressor Effects of Circulating Endothelin are Limited by its Removal in the Pulmonary Circulation and by the Release of Prostacyclin and Endothelium-Derived Relaxing Factor

Ex vivo assay to determine the cyclooxygenase selectivity of non‐steroidal anti‐inflammatory drugs

Effects of non‐steroidal anti‐inflammatory drugs on cyclo‐oxygenase and lipoxygenase activity in whole blood from aspirin‐sensitive asthmatics vs healthy donors

Selective COX‐2 inhibitors and human inflammatory bowel disease

Reduction of platelet thromboxane A2 production ex vivo and in vivo by clopidogrel therapy

Regulation and subcellular location of nitrogen oxide synthases in RAW264.7 macrophages

Perspectives of Patients With Schizophrenia and Psychiatrists Regarding Ethically Important Aspects of Research Participation

Endogenously Released Endothelin-1 from Human Pulmonary Artery Smooth Muscle Promotes Cellular Proliferation . Relevance to Pathogenesis of Pulmonary Hypertension and Vascular Remodeling

A771726, the active metabolite of leflunomide, directly inhibits the activity of cyclo‐oxygenase‐2 in vitro and in vivo in a substrate‐sensitive manner

Insulin Secretion from Pancreatic B Cells Caused by L-Arginine-Derived Nitrogen Oxides

Use of the endothelin antagonists BQ‐123 and PD 142893 to reveal three endothelin receptors mediating smooth muscle contraction and the release of EDRF

Nonsteroid Drug Selectivities for Cyclo-Oxygenase-1 Rather than Cyclo-Oxygenase-2 Are Associated with Human Gastrointestinal Toxicity: A Full in vitro Analysis

Receptor-Mediated Release of Endothelium-Derived Relaxing Factor and Prostacyclin from Bovine Aortic Endothelial Cells is Coupled

Placentally derived prostaglandin E2 acts via the EP4 receptor to inhibit IL‐2‐dependent proliferation of CTLL‐2 T cells

Expression and Activation of the Farnesoid X Receptor in the Vasculature

Aspirin and the in vitro linear relationship between thromboxane A2‐mediated platelet aggregation and platelet production of thromboxane A2

Mediation via different receptors of the vasoconstrictor effects of endothelins and sarafotoxins in the systemic circulation and renal vasculature of the anaesthetized rat

Aspirin has little additional anti‐platelet effect in healthy volunteers receiving prasugrel

Imagery rehearsal therapy for chronic nightmares in sexual assault survivors with posttraumatic stress disorder: a randomized controlled trial

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