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A natural small molecule pinocembrin resists high-fat diet-induced obesity through GPR120-ERK1/2 pathway

The Journal of nutritional biochemistry, 2024-09, Vol.135, p.109772, Article 109772

2024

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GPR120: a critical role in adipogenesis, inflammation, and energy metabolism in adipose tissue

Cellular and molecular life sciences : CMLS, 2017-08, Vol.74 (15), p.2723-2733

2017

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Loureirin B protects against obesity via activation of adipose tissue ω3 PUFA-GPR120-UCP1 axis in mice

Biochemical and biophysical research communications, 2022-12, Vol.632, p.139-149

2022

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Novel Fat Taste Receptor Agonists Curtail Progressive Weight Gain in Obese Male MiceSummary

Cellular and molecular gastroenterology and hepatology, 2023-01, Vol.15 (3), p.633-663

2023

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Gpr120 mRNA expression in gonadotropes in the mouse pituitary gland is regulated by free fatty acids

Journal of Reproduction and Development, 2020, pp.2019-166

2020

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The fungal 9‐methyl‐sphingadiene is a novel ligand for both PPARγ and GPR120

Journal of food biochemistry, 2018-10, Vol.42 (5), p.e12624-n/a

2018

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Protective role of GPR120 in the maintenance of pregnancy by promoting decidualization via regulation of glucose metabolism

EBioMedicine, 2019-01, Vol.39, p.540-551

2019

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Development of Free Fatty Acid Receptor 4 (FFA4/GPR120) Agonists in Health Science

Biomolecules & therapeutics, 2021-01, Vol.29 (1), p.22-30

2021

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Fatty Acid Taste Receptor GPR120 Activation by Arachidonic Acid, Eicosapentaenoic Acid, and Docosahexaenoic Acid in Chickens

The Journal of Poultry Science, 2021, pp.0210099

2021

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Colocalization of GPR120 and anterior pituitary hormone-producing cells in female Japanese Black cattle

Journal of Reproduction and Development, 2019, pp.2019-111

2019

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α-linolenic acid mitigates microglia-mediated neuroinflammation of schizophrenia in mice by suppressing the NF-κB/NLRP3 pathway via binding GPR120-β-arrestin 2

International immunopharmacology, 2024-12, Vol.142 (Pt A), p.113047, Article 113047

2024

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A peripheral lipid sensor GPR120 remotely contributes to suppression of PGD2-microglia-provoked neuroinflammation and neurodegeneration in the mouse hippocampus

Journal of neuroinflammation, 2021-12, Vol.18 (1), p.1-304, Article 304

2021

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Short-term but not long-term high-fat diet induces an increase in gene expression of gonadotropic hormones and GPR120 in the male mouse pituitary gland

Journal of Reproduction and Development, 2019, pp.2019-144

2019

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GPR120 modulates epileptic seizure and neuroinflammation mediated by NLRP3 inflammasome

Journal of neuroinflammation, 2022-05, Vol.19 (1), p.121-121, Article 121

2022

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G protein-coupled receptor 120 in mediating the regulation effect of saturated and unsaturated long-chain fatty acid on human adipocytes

Journal of cellular immunotherapy, 2018-09, Vol.4 (1), p.22-25

2018

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NAFLD/NASH発症におけるn-3系多価不飽和脂肪酸の関与と将来展望

YAKUGAKU ZASSHI, 2016/04/01, Vol.136(4), pp.583-589

2016

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Cellular and Molecular Mechanisms of Fat Taste Perception

Handbook of experimental pharmacology, 2022, Vol.275, p.247-270

2022

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Identification and Semi-Synthesis of 3-O-Protocatechuoylceanothic Acid, a Novel and Natural GPR120 Agonist xref rid="fn1-molecules-602982" ref-type="fn">† /xref

Molecules (Basel, Switzerland), 2019-09, Vol.24 (19), p.3487

2019

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Crosstalk between Depression, Anxiety, and Dementia: Comorbidity in Behavioral Neurology and Neuropsychiatry

Tanaka, Masaru

2022

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DHA Sensor GPR120 in Host Defense Exhibits the Dual Characteristics of Regulating Dendritic Cell Function and Skewing the Balance of Th17/Tregs

International journal of biological sciences, 2020, Vol.16 (3), p.374-387

2020

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Docosahexaenoic Acid (DHA) Induced Morphological Differentiation of Astrocytes Is Associated with Transcriptional Upregulation and Endocytosis of β 2 -AR

Molecular neurobiology, 2019-04, Vol.56 (4), p.2685

2019

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Alteration of the Glucagon Axis in GPR120 (FFAR4) Knockout Mice

The Journal of biological chemistry, 2014-05, Vol.289 (22), p.15751-15763

2014

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Drug discovery opportunities and challenges at g protein coupled receptors for long chain free Fatty acids

Frontiers in endocrinology (Lausanne), 2012, Vol.2, p.112-112

2012

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消化管脂肪酸センサーの創薬展開

YAKUGAKU ZASSHI, 2015/06/01, Vol.135(6), pp.769-777

平澤, 明

2015

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Free Fatty Acid Receptors and Their Physiological Role in Metabolic Regulation

Yakugaku zasshi, 2011-12, Vol.131 (12), p.1683-1689

2011

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A natural small molecule pinocembrin resists high-fat diet-induced obesity through GPR120-ERK1/2 pathway

GPR120: a critical role in adipogenesis, inflammation, and energy metabolism in adipose tissue

Loureirin B protects against obesity via activation of adipose tissue ω3 PUFA-GPR120-UCP1 axis in mice

Novel Fat Taste Receptor Agonists Curtail Progressive Weight Gain in Obese Male MiceSummary

Gpr120 mRNA expression in gonadotropes in the mouse pituitary gland is regulated by free fatty acids

The fungal 9‐methyl‐sphingadiene is a novel ligand for both PPARγ and GPR120

Protective role of GPR120 in the maintenance of pregnancy by promoting decidualization via regulation of glucose metabolism

Development of Free Fatty Acid Receptor 4 (FFA4/GPR120) Agonists in Health Science

Fatty Acid Taste Receptor GPR120 Activation by Arachidonic Acid, Eicosapentaenoic Acid, and Docosahexaenoic Acid in Chickens

Colocalization of GPR120 and anterior pituitary hormone-producing cells in female Japanese Black cattle

α-linolenic acid mitigates microglia-mediated neuroinflammation of schizophrenia in mice by suppressing the NF-κB/NLRP3 pathway via binding GPR120-β-arrestin 2

A peripheral lipid sensor GPR120 remotely contributes to suppression of PGD2-microglia-provoked neuroinflammation and neurodegeneration in the mouse hippocampus

Short-term but not long-term high-fat diet induces an increase in gene expression of gonadotropic hormones and GPR120 in the male mouse pituitary gland

GPR120 modulates epileptic seizure and neuroinflammation mediated by NLRP3 inflammasome

G protein-coupled receptor 120 in mediating the regulation effect of saturated and unsaturated long-chain fatty acid on human adipocytes

NAFLD/NASH発症におけるn-3系多価不飽和脂肪酸の関与と将来展望

Cellular and Molecular Mechanisms of Fat Taste Perception

Identification and Semi-Synthesis of 3-O-Protocatechuoylceanothic Acid, a Novel and Natural GPR120 Agonist xref rid="fn1-molecules-602982" ref-type="fn">† /xref

Crosstalk between Depression, Anxiety, and Dementia: Comorbidity in Behavioral Neurology and Neuropsychiatry

DHA Sensor GPR120 in Host Defense Exhibits the Dual Characteristics of Regulating Dendritic Cell Function and Skewing the Balance of Th17/Tregs

Docosahexaenoic Acid (DHA) Induced Morphological Differentiation of Astrocytes Is Associated with Transcriptional Upregulation and Endocytosis of β 2 -AR

Alteration of the Glucagon Axis in GPR120 (FFAR4) Knockout Mice

Drug discovery opportunities and challenges at g protein coupled receptors for long chain free Fatty acids

消化管脂肪酸センサーの創薬展開

Free Fatty Acid Receptors and Their Physiological Role in Metabolic Regulation

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