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Oligopeptides as Neuropeptide Y Y4 Receptor Ligands: Identification of a High-Affinity Tetrapeptide Agonist and a Hexapeptide Antagonist

Journal of medicinal chemistry, 2020-08, Vol.63 (15), p.8198-8215

2020

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UR-DEBa242: A Py-5-Labeled Fluorescent Multipurpose Probe for Investigations on the Histamine H3 and H4 Receptors

Journal of medicinal chemistry, 2020-05, Vol.63 (10), p.5297-5311

2020

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Author Correction: NanoBRET binding assay for histamine H2 receptor ligands using live recombinant HEK293T cells

Scientific reports, 2021-06, Vol.11 (1), p.12444-12444, Article 12444

2021

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Author Correction: NanoBRET binding assay for histamine H2 receptor ligands using live recombinant HEK293T cells

Scientific reports, 2021-05, Vol.11 (1), p.10747-10747, Article 10747

2021

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[3H]UR-DEBa176: A 2,4-Diaminopyrimidine-Type Radioligand Enabling Binding Studies at the Human, Mouse, and Rat Histamine H4 Receptors

Journal of medicinal chemistry, 2019-09, Vol.62 (17), p.8338-8356

2019

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The extracellular loop 2 (ECL2) of the human histamine H4 receptor substantially contributes to ligand binding and constitutive activity

PloS one, 2015, Vol.10 (1), p.e0117185

2015

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A Split Luciferase Complementation Assay for the Quantification of β-Arrestin2 Recruitment to Dopamine D2-Like Receptors

International journal of molecular sciences, 2020-08, Vol.21 (17), p.6103

2020

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Radiolabeled Dibenzodiazepinone-Type Antagonists Give Evidence of Dualsteric Binding at the M2 Muscarinic Acetylcholine Receptor

Journal of medicinal chemistry, 2017-04, Vol.60 (8), p.3314-3334

2017

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High Affinity Agonists of the Neuropeptide Y (NPY) Y4 Receptor Derived from the C‑Terminal Pentapeptide of Human Pancreatic Polypeptide (hPP): Synthesis, Stereochemical Discrimination, and Radiolabeling

Journal of medicinal chemistry, 2016-07, Vol.59 (13), p.6045-6058

2016

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Fluorescence- and Radiolabeling of [Lys4,Nle17,30]hPP Yields Molecular Tools for the NPY Y4 Receptor

Bioconjugate chemistry, 2017-04, Vol.28 (4), p.1291-1304

2017

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Red-Emitting Dibenzodiazepinone Derivatives as Fluorescent Dualsteric Probes for the Muscarinic Acetylcholine M2 Receptor

Journal of medicinal chemistry, 2020-04, Vol.63 (8), p.4133-4154

2020

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Dimeric carbamoylguanidine-type histamine H2 receptor ligands: A new class of potent and selective agonists

Bioorganic & medicinal chemistry, 2015-07, Vol.23 (14), p.3957-3969

2015

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Luciferase reporter gene assay on human, murine and rat histamine H4 receptor orthologs: correlations and discrepancies between distal and proximal readouts

PloS one, 2013, Vol.8 (9), p.e73961

2013

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Development of a Neurotensin-Derived 68Ga-Labeled PET Ligand with High In Vivo Stability for Imaging of NTS1 Receptor-Expressing Tumors

Cancers, 2022-10, Vol.14 (19), p.4922

2022

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Fluorescent H2 Receptor Squaramide-Type Antagonists: Synthesis, Characterization, and Applications

ACS medicinal chemistry letters, 2020-08, Vol.11 (8), p.1521-1528

2020

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The Neuropeptide Y Y1 Receptor: A Diagnostic Marker? Expression in MCF-7 Breast Cancer Cells Is Down-Regulated by Antiestrogens In Vitro and in Xenografts

PloS one, 2012-12, Vol.7 (12), p.e51032

2012

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Modular synthesis of non-peptidic bivalent NPY Y1 receptor antagonists

Bioorganic & medicinal chemistry, 2008-11, Vol.16 (22), p.9858-9866

2008

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Prototypic 18F‑Labeled Argininamide-Type Neuropeptide Y Y1R Antagonists as Tracers for PET Imaging of Mammary Carcinoma

ACS medicinal chemistry letters, 2017-03, Vol.8 (3), p.304-309

2017

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The Bivalent Ligand Approach Leads to Highly Potent and Selective Acylguanidine-Type Histamine H2 Receptor Agonists

Journal of medicinal chemistry, 2012-02, Vol.55 (3), p.1147-1160

2012

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[3H]UR-MK136: A Highly Potent and Selective Radioligand for Neuropeptide Y Y1 Receptors

ChemMedChem, 2011-09, Vol.6 (9), p.1566-1571

2011

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Fluorescence-and luminescence-based methods for the determination of affinity and activity of neuropeptide Y2 receptor ligands

European journal of pharmacology, 2006-12, Vol.551 (1-3), p.10-18

2006

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[3H]UR-DE257: Development of a Tritium-Labeled Squaramide-Type Selective Histamine H2 Receptor Antagonist

ChemMedChem, 2015-01, Vol.10 (1), p.83-93

2015

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Application of the Guanidine-Acylguanidine Bioisosteric Approach to Argininamide-Type NPY Y2 Receptor Antagonists

ChemMedChem, 2011-09, Vol.6 (9), p.1727-1738

2011

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Toward Labeled Argininamide-Type NPY Y1 Receptor Antagonists: Identification of a Favorable Propionylation Site in BIBO3304

Archiv der Pharmazie (Weinheim), 2015-06, Vol.348 (6), p.390-398

2015

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Modifications at Arg and Ile Give Neurotensin(8-13) Derivatives with High Stability and Retained NTS 1 Receptor Affinity

ACS medicinal chemistry letters, 2019-06, Vol.10 (6), p.960-965

2019

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Oligopeptides as Neuropeptide Y Y4 Receptor Ligands: Identification of a High-Affinity Tetrapeptide Agonist and a Hexapeptide Antagonist

UR-DEBa242: A Py-5-Labeled Fluorescent Multipurpose Probe for Investigations on the Histamine H3 and H4 Receptors

Author Correction: NanoBRET binding assay for histamine H2 receptor ligands using live recombinant HEK293T cells

Author Correction: NanoBRET binding assay for histamine H2 receptor ligands using live recombinant HEK293T cells

[3H]UR-DEBa176: A 2,4-Diaminopyrimidine-Type Radioligand Enabling Binding Studies at the Human, Mouse, and Rat Histamine H4 Receptors

The extracellular loop 2 (ECL2) of the human histamine H4 receptor substantially contributes to ligand binding and constitutive activity

A Split Luciferase Complementation Assay for the Quantification of β-Arrestin2 Recruitment to Dopamine D2-Like Receptors

Radiolabeled Dibenzodiazepinone-Type Antagonists Give Evidence of Dualsteric Binding at the M2 Muscarinic Acetylcholine Receptor

High Affinity Agonists of the Neuropeptide Y (NPY) Y4 Receptor Derived from the C‑Terminal Pentapeptide of Human Pancreatic Polypeptide (hPP): Synthesis, Stereochemical Discrimination, and Radiolabeling

Fluorescence- and Radiolabeling of [Lys4,Nle17,30]hPP Yields Molecular Tools for the NPY Y4 Receptor

Red-Emitting Dibenzodiazepinone Derivatives as Fluorescent Dualsteric Probes for the Muscarinic Acetylcholine M2 Receptor

Dimeric carbamoylguanidine-type histamine H2 receptor ligands: A new class of potent and selective agonists

Luciferase reporter gene assay on human, murine and rat histamine H4 receptor orthologs: correlations and discrepancies between distal and proximal readouts

Development of a Neurotensin-Derived 68Ga-Labeled PET Ligand with High In Vivo Stability for Imaging of NTS1 Receptor-Expressing Tumors

Fluorescent H2 Receptor Squaramide-Type Antagonists: Synthesis, Characterization, and Applications

The Neuropeptide Y Y1 Receptor: A Diagnostic Marker? Expression in MCF-7 Breast Cancer Cells Is Down-Regulated by Antiestrogens In Vitro and in Xenografts

Modular synthesis of non-peptidic bivalent NPY Y1 receptor antagonists

Prototypic 18F‑Labeled Argininamide-Type Neuropeptide Y Y1R Antagonists as Tracers for PET Imaging of Mammary Carcinoma

The Bivalent Ligand Approach Leads to Highly Potent and Selective Acylguanidine-Type Histamine H2 Receptor Agonists

[3H]UR-MK136: A Highly Potent and Selective Radioligand for Neuropeptide Y Y1 Receptors

Fluorescence-and luminescence-based methods for the determination of affinity and activity of neuropeptide Y2 receptor ligands

[3H]UR-DE257: Development of a Tritium-Labeled Squaramide-Type Selective Histamine H2 Receptor Antagonist

Application of the Guanidine-Acylguanidine Bioisosteric Approach to Argininamide-Type NPY Y2 Receptor Antagonists

Toward Labeled Argininamide-Type NPY Y1 Receptor Antagonists: Identification of a Favorable Propionylation Site in BIBO3304

Modifications at Arg and Ile Give Neurotensin(8-13) Derivatives with High Stability and Retained NTS 1 Receptor Affinity

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