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Software for systems biology: from tools to integrated platforms

Nature reviews. Genetics, 2011-12, Vol.12 (12), p.821

2011

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Potential Functional Restoration of Corneal Endothelial Cells in Fuchs Endothelial Corneal Dystrophy by ROCK Inhibitor (Ripasudil)

American journal of ophthalmology, 2021-04, Vol.224, p.185-199

2021

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Gankyrin drives metabolic reprogramming to promote tumorigenesis, metastasis and drug resistance through activating β-catenin/c-Myc signaling in human hepatocellular carcinoma

Cancer letters, 2019-02, Vol.443, p.34-46

2019

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Activation of the integrated stress response in human hair follicles

PloS one, 2024-06, Vol.19 (6), p.e0303742

2024

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Single-cell sequencing reveals karyotype heterogeneity in murine and human malignancies

Genome Biology, 2016-05, Vol.17 (1), p.115-115, Article 115

2016

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Cell Origin Dictates Programming of Resident versus Recruited Macrophages during Acute Lung Injury

American journal of respiratory cell and molecular biology, 2017-09, Vol.57 (3), p.294-306

2017

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A Cyclin A-Myb-MuvB-Aurora B network regulates the choice between mitotic cycles and polyploid endoreplication cycles

PLoS genetics, 2019-07, Vol.15 (7), p.e1008253

2019

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Genome-wide identification of transcription factors that are critical to non-small cell lung cancer

Cancer letters, 2018-10, Vol.434, p.132-143

2018

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Time of day and network reprogramming during drought induced CAM photosynthesis in Sedum album

PLoS genetics, 2019-06, Vol.15 (6), p.e1008209

2019

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CPF impedes cell cycle re‐entry of quiescent lung cancer cells through transcriptional suppression of FACT and c‐MYC

Journal of cellular and molecular medicine, 2020-02, Vol.24 (3), p.2229-2239

2020

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TAS‐116 (pimitespib), a heat shock protein 90 inhibitor, shows efficacy in preclinical models of adult T‐cell leukemia

Cancer science, 2022-02, Vol.113 (2), p.684-696

2022

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In vitro anticancer properties and biological evaluation of novel natural alkaloid jerantinine B

Cancer letters, 2016-01, Vol.370 (2), p.185-197

2016

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Oxidative stress-induced downregulation of glycogen synthase kinase 3 beta in fetal membranes promotes cellular senescence

Biology of reproduction, 2019-11, Vol.101 (5), p.1018-1030

2019

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IKAP: A heuristic framework for inference of kinase activities from Phosphoproteomics data

Bioinformatics, 2016-02, Vol.32 (3), p.424-431

2016

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Cuproptosis identifies respiratory subtype of renal cancer that confers favorable prognosis

Apoptosis (London), 2022-12, Vol.27 (11-12), p.1004-1014

2022

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AZD1775 and anti-PD-1 antibody synergistically sensitize hepatoma to radiotherapy

Chinese medical journal, 2024-01, Vol.137 (2), p.222-231

2024

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PI3K blockage synergizes with PLK1 inhibition preventing endoreduplication and enhancing apoptosis in anaplastic thyroid cancer

Cancer letters, 2018-12, Vol.439, p.56-65

2018

Volltextzugriff (PDF)

Using ToxCast™ Data to Reconstruct Dynamic Cell State Trajectories and Estimate Toxicological Points of Departure

Environmental health perspectives, 2016-07, Vol.124 (7), p.910-919

2016

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Systemic alterations of tricarboxylic acid cycle enzymes in Alzheimer's disease

Frontiers in neuroscience, 2023-07, Vol.17, p.1206688-1206688

2023

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MicroRNA‑16‑5p regulates cell survival, cell cycle and apoptosis by targeting AKT3 in prostate cancer cells

Oncology reports, 2020-09, Vol.44 (3), p.1282-1292

2020

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Efficacy of combined targeted therapy with PI3K and CDK4/6 or PARP and WEE1 inhibitors in neuroblastoma cell lines

Oncology reports, 2023-09, Vol.50 (3), p.1, Article 166

2023

Volltextzugriff (PDF)

Reusable rule-based cell cycle model explains compartment-resolved dynamics of 16 observables in RPE-1 cells

PLoS computational biology, 2024-01, Vol.20 (1), p.e1011151-e1011151

2024

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Targeting CXCR4 abrogates resistance to trastuzumab by blocking cell cycle progression and synergizes with docetaxel in breast cancer treatment

Breast cancer research : BCR, 2023-06, Vol.25 (1), p.62-62, Article 62

2023

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Phytochemical Analysis and Anti-Inflammatory Activity of Different Ethanolic Phyto-Extracts of Artemisia annua L

Biomolecules (Basel, Switzerland), 2021-07, Vol.11 (7), p.975

2021

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Targeting oxidative pentose phosphate pathway prevents recurrence in mutant Kras colorectal carcinomas

PLoS biology, 2019-08, Vol.17 (8), p.e3000425-e3000425

2019

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Software for systems biology: from tools to integrated platforms

Potential Functional Restoration of Corneal Endothelial Cells in Fuchs Endothelial Corneal Dystrophy by ROCK Inhibitor (Ripasudil)

Gankyrin drives metabolic reprogramming to promote tumorigenesis, metastasis and drug resistance through activating β-catenin/c-Myc signaling in human hepatocellular carcinoma

Activation of the integrated stress response in human hair follicles

Single-cell sequencing reveals karyotype heterogeneity in murine and human malignancies

Cell Origin Dictates Programming of Resident versus Recruited Macrophages during Acute Lung Injury

A Cyclin A-Myb-MuvB-Aurora B network regulates the choice between mitotic cycles and polyploid endoreplication cycles

Genome-wide identification of transcription factors that are critical to non-small cell lung cancer

Time of day and network reprogramming during drought induced CAM photosynthesis in Sedum album

CPF impedes cell cycle re‐entry of quiescent lung cancer cells through transcriptional suppression of FACT and c‐MYC

TAS‐116 (pimitespib), a heat shock protein 90 inhibitor, shows efficacy in preclinical models of adult T‐cell leukemia

In vitro anticancer properties and biological evaluation of novel natural alkaloid jerantinine B

Oxidative stress-induced downregulation of glycogen synthase kinase 3 beta in fetal membranes promotes cellular senescence

IKAP: A heuristic framework for inference of kinase activities from Phosphoproteomics data

Cuproptosis identifies respiratory subtype of renal cancer that confers favorable prognosis

AZD1775 and anti-PD-1 antibody synergistically sensitize hepatoma to radiotherapy

PI3K blockage synergizes with PLK1 inhibition preventing endoreduplication and enhancing apoptosis in anaplastic thyroid cancer

Using ToxCast™ Data to Reconstruct Dynamic Cell State Trajectories and Estimate Toxicological Points of Departure

Systemic alterations of tricarboxylic acid cycle enzymes in Alzheimer's disease

MicroRNA‑16‑5p regulates cell survival, cell cycle and apoptosis by targeting AKT3 in prostate cancer cells

Efficacy of combined targeted therapy with PI3K and CDK4/6 or PARP and WEE1 inhibitors in neuroblastoma cell lines

Reusable rule-based cell cycle model explains compartment-resolved dynamics of 16 observables in RPE-1 cells

Targeting CXCR4 abrogates resistance to trastuzumab by blocking cell cycle progression and synergizes with docetaxel in breast cancer treatment

Phytochemical Analysis and Anti-Inflammatory Activity of Different Ethanolic Phyto-Extracts of Artemisia annua L

Targeting oxidative pentose phosphate pathway prevents recurrence in mutant Kras colorectal carcinomas

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