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Structure-activity relationships of GPR120 agonists based on a docking simulation

Molecular pharmacology, 2010-11, Vol.78 (5), p.804-810

2010

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GPR120/FFAR4: A Potential New Therapeutic Target for Inflammatory Bowel Disease

Inflammatory bowel diseases, 2023-12, Vol.29 (12), p.1981-1989

2023

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GPR120: a critical role in adipogenesis, inflammation, and energy metabolism in adipose tissue

Cellular and molecular life sciences : CMLS, 2017-08, Vol.74 (15), p.2723-2733

2017

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Positive Reinforcing Mechanisms between GPR120 and PPARγ Modulate Insulin Sensitivity

Cell metabolism, 2020-06, Vol.31 (6), p.1173-1188.e5

2020

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Loureirin B protects against obesity via activation of adipose tissue ω3 PUFA-GPR120-UCP1 axis in mice

Biochemical and biophysical research communications, 2022-12, Vol.632, p.139-149

2022

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DHA supplementation prevent the progression of NASH via GPR120 signaling

European journal of pharmacology, 2018-02, Vol.820, p.31-38

2018

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Gpr120 mRNA expression in gonadotropes in the mouse pituitary gland is regulated by free fatty acids

Journal of Reproduction and Development, 2020, pp.2019-166

2020

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The fungal 9‐methyl‐sphingadiene is a novel ligand for both PPARγ and GPR120

Journal of food biochemistry, 2018-10, Vol.42 (5), p.e12624-n/a

2018

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Vaccarin improves insulin sensitivity and glucose uptake in diet-induced obese mice via activation of GPR120-PI3K/AKT/GLUT4 pathway

Biochemical and biophysical research communications, 2022-12, Vol.634, p.189-195

2022

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Docosahexaenoic Acid Inhibits Inflammation-Induced Osteoclast Formation and Bone Resorption in vivo Through GPR120 by Inhibiting TNF-α Production in Macrophages and Directly Inhibiting Osteoclast Formation

Frontiers in endocrinology (Lausanne), 2019-03, Vol.10, p.157-157

2019

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Nutritional Signaling via Free Fatty Acid Receptors

International Journal of Molecular Sciences, 2016-03, Vol.17 (4), p.450-450

2016

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In silico and in vitro screening for potential anticancer candidates targeting GPR120

Bioorganic & medicinal chemistry letters, 2021-01, Vol.31, p.127672, Article 127672

2021

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GPR120/FFAR4 stimulation attenuates airway remodeling and suppresses IL-4- and IL-13-induced airway epithelial injury via inhibition of STAT6 and Akt

Biomedicine & pharmacotherapy, 2023-12, Vol.168, p.115774-115774, Article 115774

2023

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Oral administration of linoleic acid immediately before glucose load ameliorates postprandial hyperglycemia

Frontiers in pharmacology, 2023-07, Vol.14, p.1197743-1197743

2023

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Fatty acid taste quality information via GPR120 in the anterior tongue of mice

Acta Physiologica, 2019-05, Vol.226 (1), p.e13215-n/a

2019

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Linoleic acid promotes testosterone production by activating Leydig cell GPR120/ ERK pathway and restores BPA-impaired testicular toxicity

Steroids, 2020-11, Vol.163, p.108677-108677, Article 108677

2020

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Dipeptidyl peptidase-4 and GLP-1 interplay in STC-1 and GLUTag cell lines

Peptides (New York, N.Y. : 1980), 2020-12, Vol.134, p.170419-170419, Article 170419

2020

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FFA4 (GPR120) as a fatty acid sensor involved in appetite control, insulin sensitivity and inflammation regulation

Molecular aspects of medicine, 2018-12, Vol.64, p.92-108

Im, Dong-Soon

2018

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Protective role of GPR120 in the maintenance of pregnancy by promoting decidualization via regulation of glucose metabolism

EBioMedicine, 2019-01, Vol.39, p.540-551

2019

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Immunomodulatory Activity of Docosahexenoic Acid on RAW264.7 Cells Activation through GPR120-Mediated Signaling Pathway

Journal of agricultural and food chemistry, 2018-01, Vol.66 (4), p.926-934

2018

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Predictive value of first-trimester GPR120 levels in gestational diabetes mellitus

Frontiers in endocrinology (Lausanne), 2023-09, Vol.14, p.1220472-1220472

2023

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GPR120 agonists enhance the fatty orosensation when added to fat-containing system, but do not evoke it by themselves in humans

Physiology & behavior, 2021-05, Vol.234, p.113383-113383, Article 113383

2021

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Effects of TUG-891, a potent GPR120 agonist, on the physical and oral lipid- coating properties, and secretion of saliva

Physiology & behavior, 2023-06, Vol.265, p.114160-114160, Article 114160

2023

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Use of Surface-Enhanced Raman Scattering (SERS) Probes to Detect Fatty Acid Receptor Activity in a Microfluidic Device

Sensors (Basel, Switzerland), 2019-04, Vol.19 (7), p.1663

2019

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An atlas of GPCRs in dopamine neurons: Identification of the free fatty acid receptor 4 as a regulator of food and water intake

Cell reports (Cambridge), 2024-07, Vol.43 (7), p.114509, Article 114509

2024

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Structure-activity relationships of GPR120 agonists based on a docking simulation

GPR120/FFAR4: A Potential New Therapeutic Target for Inflammatory Bowel Disease

GPR120: a critical role in adipogenesis, inflammation, and energy metabolism in adipose tissue

Positive Reinforcing Mechanisms between GPR120 and PPARγ Modulate Insulin Sensitivity

Loureirin B protects against obesity via activation of adipose tissue ω3 PUFA-GPR120-UCP1 axis in mice

DHA supplementation prevent the progression of NASH via GPR120 signaling

Gpr120 mRNA expression in gonadotropes in the mouse pituitary gland is regulated by free fatty acids

The fungal 9‐methyl‐sphingadiene is a novel ligand for both PPARγ and GPR120

Vaccarin improves insulin sensitivity and glucose uptake in diet-induced obese mice via activation of GPR120-PI3K/AKT/GLUT4 pathway

Docosahexaenoic Acid Inhibits Inflammation-Induced Osteoclast Formation and Bone Resorption in vivo Through GPR120 by Inhibiting TNF-α Production in Macrophages and Directly Inhibiting Osteoclast Formation

Nutritional Signaling via Free Fatty Acid Receptors

In silico and in vitro screening for potential anticancer candidates targeting GPR120

GPR120/FFAR4 stimulation attenuates airway remodeling and suppresses IL-4- and IL-13-induced airway epithelial injury via inhibition of STAT6 and Akt

Oral administration of linoleic acid immediately before glucose load ameliorates postprandial hyperglycemia

Fatty acid taste quality information via GPR120 in the anterior tongue of mice

Linoleic acid promotes testosterone production by activating Leydig cell GPR120/ ERK pathway and restores BPA-impaired testicular toxicity

Dipeptidyl peptidase-4 and GLP-1 interplay in STC-1 and GLUTag cell lines

FFA4 (GPR120) as a fatty acid sensor involved in appetite control, insulin sensitivity and inflammation regulation

Protective role of GPR120 in the maintenance of pregnancy by promoting decidualization via regulation of glucose metabolism

Immunomodulatory Activity of Docosahexenoic Acid on RAW264.7 Cells Activation through GPR120-Mediated Signaling Pathway

Predictive value of first-trimester GPR120 levels in gestational diabetes mellitus

GPR120 agonists enhance the fatty orosensation when added to fat-containing system, but do not evoke it by themselves in humans

Effects of TUG-891, a potent GPR120 agonist, on the physical and oral lipid- coating properties, and secretion of saliva

Use of Surface-Enhanced Raman Scattering (SERS) Probes to Detect Fatty Acid Receptor Activity in a Microfluidic Device

An atlas of GPCRs in dopamine neurons: Identification of the free fatty acid receptor 4 as a regulator of food and water intake

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