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A natural small molecule pinocembrin resists high-fat diet-induced obesity through GPR120-ERK1/2 pathway

The Journal of nutritional biochemistry, 2024-09, Vol.135, p.109772, Article 109772

2024

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Loureirin B protects against obesity via activation of adipose tissue ω3 PUFA-GPR120-UCP1 axis in mice

Biochemical and biophysical research communications, 2022-12, Vol.632, p.139-149

2022

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DHA supplementation prevent the progression of NASH via GPR120 signaling

European journal of pharmacology, 2018-02, Vol.820, p.31-38

2018

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Vaccarin improves insulin sensitivity and glucose uptake in diet-induced obese mice via activation of GPR120-PI3K/AKT/GLUT4 pathway

Biochemical and biophysical research communications, 2022-12, Vol.634, p.189-195

2022

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Free-Fatty Acid Receptor-4 (FFA4/GPR120) differentially regulates migration, invasion, proliferation and tumor growth of papillary renal cell carcinoma cells

Biochemical pharmacology, 2023-07, Vol.213, p.115590-115590, Article 115590

2023

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Positive interplay between FFAR4/GPR120, DPP-IV inhibition and GLP-1 in beta cell proliferation and glucose homeostasis in obese high fat fed mice

Peptides (New York, N.Y. : 1980), 2024-07, Vol.177, p.171218, Article 171218

2024

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In silico and in vitro screening for potential anticancer candidates targeting GPR120

Bioorganic & medicinal chemistry letters, 2021-01, Vol.31, p.127672, Article 127672

2021

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GPR120/FFAR4 stimulation attenuates airway remodeling and suppresses IL-4- and IL-13-induced airway epithelial injury via inhibition of STAT6 and Akt

Biomedicine & pharmacotherapy, 2023-12, Vol.168, p.115774-115774, Article 115774

2023

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Dipeptidyl peptidase-4 and GLP-1 interplay in STC-1 and GLUTag cell lines

Peptides (New York, N.Y. : 1980), 2020-12, Vol.134, p.170419-170419, Article 170419

2020

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Linoleic acid promotes testosterone production by activating Leydig cell GPR120/ ERK pathway and restores BPA-impaired testicular toxicity

Steroids, 2020-11, Vol.163, p.108677-108677, Article 108677

2020

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FFA4 (GPR120) as a fatty acid sensor involved in appetite control, insulin sensitivity and inflammation regulation

Molecular aspects of medicine, 2018-12, Vol.64, p.92-108

Im, Dong-Soon

2018

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GPR120 agonists enhance the fatty orosensation when added to fat-containing system, but do not evoke it by themselves in humans

Physiology & behavior, 2021-05, Vol.234, p.113383-113383, Article 113383

2021

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Effects of TUG-891, a potent GPR120 agonist, on the physical and oral lipid- coating properties, and secretion of saliva

Physiology & behavior, 2023-06, Vol.265, p.114160-114160, Article 114160

2023

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Functions of omega-3 fatty acids and FFA4 (GPR120) in macrophages

European journal of pharmacology, 2016-08, Vol.785, p.36-43

Im, Dong-Soon

2016

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Oncogenic signaling of the free-fatty acid receptors FFA1 and FFA4 in human breast carcinoma cells

Biochemical pharmacology, 2022-12, Vol.206, p.115328, Article 115328

2022

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Enzymatically-epoxidized docosahexaenoic acid, 19,20-EpDPE, suppresses hepatic crown-like structure formation and nonalcoholic steatohepatitis fibrosis through GPR120

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2023-03, Vol.1868 (3), p.159275-159275, Article 159275

2023

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Identification and target-pathway deconvolution of FFA4 agonists with anti-diabetic activity from Arnebia euchroma (Royle) Johnst

Pharmacological research, 2021-01, Vol.163, p.105173-105173, Article 105173

2021

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Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120)

Bioorganic & medicinal chemistry letters, 2014-07, Vol.24 (14), p.3100-3103

2014

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Free-fatty acid receptor-4 (GPR120): Cellular and molecular function and its role in metabolic disorders

Biochemical pharmacology, 2016-06, Vol.110-111, p.1-15

Moniri, Nader H.

2016

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Fat taste signal transduction and its possible negative modulator components

Progress in lipid research, 2020-07, Vol.79, p.101035-101035, Article 101035

2020

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Adaptive thermogenesis by dietary n-3 polyunsaturated fatty acids: Emerging evidence and mechanisms

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2019-01, Vol.1864 (1), p.59-70

2019

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Discovery of novel selective GPR120 agonists with potent anti-diabetic activity by hybrid design

Bioorganic & medicinal chemistry letters, 2018-08, Vol.28 (15), p.2599-2604

2018

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Omega-3 fatty acids in anti-inflammation (pro-resolution) and GPCRs

Progress in lipid research, 2012-07, Vol.51 (3), p.232-237

Im, Dong-Soon

2012

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Pinocembrin and its linolenoyl ester derivative induce wound healing activity in HaCaT cell line potentially involving a GPR120/FFA4 mediated pathway

Bioorganic chemistry, 2021-03, Vol.108, p.104657, Article 104657

2021

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9-PAHSA promotes browning of white fat via activating G-protein-coupled receptor 120 and inhibiting lipopolysaccharide / NF-kappa B pathway

Biochemical and biophysical research communications, 2018-11, Vol.506 (1), p.153-160

2018

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A natural small molecule pinocembrin resists high-fat diet-induced obesity through GPR120-ERK1/2 pathway

Loureirin B protects against obesity via activation of adipose tissue ω3 PUFA-GPR120-UCP1 axis in mice

DHA supplementation prevent the progression of NASH via GPR120 signaling

Vaccarin improves insulin sensitivity and glucose uptake in diet-induced obese mice via activation of GPR120-PI3K/AKT/GLUT4 pathway

Free-Fatty Acid Receptor-4 (FFA4/GPR120) differentially regulates migration, invasion, proliferation and tumor growth of papillary renal cell carcinoma cells

Positive interplay between FFAR4/GPR120, DPP-IV inhibition and GLP-1 in beta cell proliferation and glucose homeostasis in obese high fat fed mice

In silico and in vitro screening for potential anticancer candidates targeting GPR120

GPR120/FFAR4 stimulation attenuates airway remodeling and suppresses IL-4- and IL-13-induced airway epithelial injury via inhibition of STAT6 and Akt

Dipeptidyl peptidase-4 and GLP-1 interplay in STC-1 and GLUTag cell lines

Linoleic acid promotes testosterone production by activating Leydig cell GPR120/ ERK pathway and restores BPA-impaired testicular toxicity

FFA4 (GPR120) as a fatty acid sensor involved in appetite control, insulin sensitivity and inflammation regulation

GPR120 agonists enhance the fatty orosensation when added to fat-containing system, but do not evoke it by themselves in humans

Effects of TUG-891, a potent GPR120 agonist, on the physical and oral lipid- coating properties, and secretion of saliva

Functions of omega-3 fatty acids and FFA4 (GPR120) in macrophages

Oncogenic signaling of the free-fatty acid receptors FFA1 and FFA4 in human breast carcinoma cells

Enzymatically-epoxidized docosahexaenoic acid, 19,20-EpDPE, suppresses hepatic crown-like structure formation and nonalcoholic steatohepatitis fibrosis through GPR120

Identification and target-pathway deconvolution of FFA4 agonists with anti-diabetic activity from Arnebia euchroma (Royle) Johnst

Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120)

Free-fatty acid receptor-4 (GPR120): Cellular and molecular function and its role in metabolic disorders

Fat taste signal transduction and its possible negative modulator components

Adaptive thermogenesis by dietary n-3 polyunsaturated fatty acids: Emerging evidence and mechanisms

Discovery of novel selective GPR120 agonists with potent anti-diabetic activity by hybrid design

Omega-3 fatty acids in anti-inflammation (pro-resolution) and GPCRs

Pinocembrin and its linolenoyl ester derivative induce wound healing activity in HaCaT cell line potentially involving a GPR120/FFA4 mediated pathway

9-PAHSA promotes browning of white fat via activating G-protein-coupled receptor 120 and inhibiting lipopolysaccharide / NF-kappa B pathway

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